RNF20-RNF40: A ubiquitin-driven link between gene expression and the DNA damage response

Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response

(2011) Maayan Salton et al.   CELL CYCLE

Chromatin dynamics and the repair of DNA double strand breaks

(2011) Ye Xu et al.   CELL CYCLE

Chromatin: constructing the big picture

(2011) Bas van Steensel   EMBO JOURNAL

Beyond ATM: The protein kinase landscape of the DNA damage response

(2011) Ariel Bensimon et al.   FEBS LETTERS

The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks

(2011) Simon Bekker-Jensen et al.   FEBS LETTERS

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

Regulation of Homologous Recombination by RNF20-Dependent H2B Ubiquitination

(2011) Kyosuke Nakamura et al.   MOLECULAR CELL

RNF20 Inhibits TFIIS-Facilitated Transcriptional Elongation to Suppress Pro-oncogenic Gene Expression

(2011) Efrat Shema et al.   MOLECULAR CELL

WAC, a Functional Partner of RNF20/40, Regulates Histone H2B Ubiquitination and Gene Transcription

(2011) Feng Zhang et al.   MOLECULAR CELL

Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks

(2011) Lilach Moyal et al.   MOLECULAR CELL

Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction

(2011) Beat Fierz et al.   Nature Chemical Biology

The MRE11 complex: starting from the ends

(2011) Travis H. Stracker et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

The Human PAF1 Complex Acts in Chromatin Transcription Elongation Both Independently and Cooperatively with SII/TFIIS

(2010) Jaehoon Kim et al.   CELL

ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks

(2010) Niraj M. Shanbhag et al.   CELL

Epigenetic Modifications in Double-Strand Break DNA Damage Signaling and Repair

(2010) D. Rossetto et al.   CLINICAL CANCER RESEARCH

The Mi-2-like Smed-CHD4 gene is required for stem cell differentiation in the planarian Schmidtea mediterranea

(2010) M. L. Scimone et al.   DEVELOPMENT

Coping with DNA double strand breaks

(2010) Kevin Hiom   DNA REPAIR

The ATR barrier to replication-born DNA damage

(2010) Andrés J. López-Contreras et al.   DNA REPAIR

Regulation of DNA strand exchange in homologous recombination

(2010) J. Thomas Holthausen et al.   DNA REPAIR

Assembly and function of DNA double-strand break repair foci in mammalian cells

(2010) Simon Bekker-Jensen et al.   DNA REPAIR

Open, repair and close again: Chromatin dynamics and the response to UV-induced DNA damage

(2010) Zoraya Palomera-Sanchez et al.   DNA REPAIR

Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4

(2010) Sophie E Polo et al.   EMBO JOURNAL

Core histone H2A ubiquitylation and transcriptional regulation

(2010) Miki Higashi et al.   EXPERIMENTAL CELL RESEARCH

Multiple roles of ATM in monitoring and maintaining DNA integrity

(2010) Frederick A. Derheimer et al.   FEBS LETTERS

The MRN complex in double-strand break repair and telomere maintenance

(2010) Brandon J. Lamarche et al.   FEBS LETTERS

The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair

(2010) Ye Xu et al.   JOURNAL OF CELL BIOLOGY

The NuRD chromatin–remodeling complex regulates signaling and repair of DNA damage

(2010) Godelieve Smeenk et al.   JOURNAL OF CELL BIOLOGY

The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage

(2010) Dorthe Helena Larsen et al.   JOURNAL OF CELL BIOLOGY

The Chromatin Signaling Pathway: Diverse Mechanisms of Recruitment of Histone-Modifying Enzymes and Varied Biological Outcomes

(2010) Edwin Smith et al.   MOLECULAR CELL

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Higher-order chromatin structure in DSB induction, repair and misrepair

(2010) Martin Falk et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair

(2010) Angela T. Noon et al.   NATURE CELL BIOLOGY

Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation

(2010) Champak Chatterjee et al.   Nature Chemical Biology

A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

(2010) D. M. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deficiency in Bre1 Impairs Homologous Recombination Repair and Cell Cycle Checkpoint Response to Radiation Damage in Mammalian Cells

(2010) Sophia B. Chernikova et al.   RADIATION RESEARCH

Structural Insights into the Assembly and Function of the SAGA Deubiquitinating Module

(2010) N. L. Samara et al.   SCIENCE

ATM-Dependent and -Independent Dynamics of the Nuclear Phosphoproteome After DNA Damage

(2010) A. Bensimon et al.   Science Signaling

ATR: a master conductor of cellular responses to DNA replication stress

(2010) Rachel Litman Flynn et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mechanisms of double-strand break repair in somatic mammalian cells

(2009) Andrea J. Hartlerode et al.   BIOCHEMICAL JOURNAL

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

(2009) Grant S. Stewart et al.   CELL

RAD6-Mediated Transcription-Coupled H2B Ubiquitylation Directly Stimulates H3K4 Methylation in Human Cells

(2009) Jaehoon Kim et al.   CELL

Telomeres, histone code, and DNA damage response

(2009) S. Misri et al.   CYTOGENETIC AND GENOME RESEARCH

The role of RAD6 in recombinational repair, checkpoints and meiosis via histone modification

(2009) John C. Game et al.   DNA REPAIR

Common mechanisms of PIKK regulation

(2009) Courtney A. Lovejoy et al.   DNA REPAIR

Emerging common themes in regulation of PIKKs and PI3Ks

(2009) Harri Lempiäinen et al.   EMBO JOURNAL

A histone code for the DNA damage response in mammalian cells?

(2009) Armelle Corpet et al.   EMBO JOURNAL

Transcription arrest relief by S-II/TFIIS during gene expression in erythroblast differentiation

(2009) Makiko Nagata et al.   GENES TO CELLS

Role of polycomb proteins Ring1A and Ring1Bin the epigenetic regulation of gene expression

(2009) Miguel Vidal   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

The comet assay: A sensitive method for detecting DNA damage in individual cells

(2009) Wenjuan Liao et al.   METHODS

BBAP Monoubiquitylates Histone H4 at Lysine 91 and Selectively Modulates the DNA Damage Response

(2009) Qingsheng Yan et al.   MOLECULAR CELL

Linking Cell Cycle to Histone Modifications: SBF and H2B Monoubiquitination Machinery and Cell-Cycle Regulation of H3K79 Dimethylation

(2009) Julia M. Schulze et al.   MOLECULAR CELL

Dealing with DNA damage: Relationships between checkpoint and repair pathways

(2009) Daniël O. Warmerdam et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

The cap binding complex influences H2B ubiquitination by facilitating splicing of the SUS1 pre-mRNA

(2009) M. A. Hossain et al.   RNA

Crosstalk between histone modifications during the DNA damage response

(2009) Haico van Attikum et al.   TRENDS IN CELL BIOLOGY

Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis

(2008) Kyle Hubbard et al.   BMC CANCER

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression

(2008) E. Shema et al.   GENES & DEVELOPMENT

Regulation of TIP60 by ATF2 Modulates ATM Activation

(2008) Anindita Bhoumik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Di-methyl H4 Lysine 20 Targets the Checkpoint Protein Crb2 to Sites of DNA Damage

(2008) Nikole T. Greeson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin

(2008) Aaron A. Goodarzi et al.   MOLECULAR CELL

Histone Ubiquitination: Triggering Gene Activity

(2008) Vikki M. Weake et al.   MOLECULAR CELL

H2B Ubiquitylation Plays a Role in Nucleosome Dynamics during Transcription Elongation

(2008) Alastair B. Fleming et al.   MOLECULAR CELL

What histone code for DNA repair?

(2008) Alexandre E. Escargueil et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

HP1-β mobilization promotes chromatin changes that initiate the DNA damage response

(2008) Nabieh Ayoub et al.   NATURE

Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells

(2008) Neri Minsky et al.   NATURE CELL BIOLOGY

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

(2008) Martin F. Lavin   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE