Flavones induce neutrophil apoptosis by down-regulation of Mcl-1 via a proteasomal-dependent pathway

Flavonoid intake and cardiovascular disease mortality in a prospective cohort of US adults

(2012) Marjorie L McCullough et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections

(2012) David M. Tobin et al.   CELL

Infection regulates pro-resolving mediators that lower antibiotic requirements

(2012) Nan Chiang et al.   NATURE

Imaging inflammation: Molecular strategies to visualize key components of the inflammatory cascade, from initiation to resolution

(2012) D.A. Dorward et al.   PHARMACOLOGY & THERAPEUTICS

Baicalin Improves Survival in a Murine Model of Polymicrobial Sepsis via Suppressing Inflammatory Response and Lymphocyte Apoptosis

(2012) Jiali Zhu et al.   PLoS One

Intracellular zinc release-activated ERK-dependent GSK-3β–p53 and Noxa–Mcl-1 signaling are both involved in cardiac ischemic-reperfusion injury

(2011) C-L Lin et al.   CELL DEATH AND DIFFERENTIATION

Luteolin improves contractile function and attenuates apoptosis following ischemia–reperfusion in adult rat cardiomyocytes

(2011) Lingling Qi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Luteolin attenuates the pulmonary inflammatory response involves abilities of antioxidation and inhibition of MAPK and NFκB pathways in mice with endotoxin-induced acute lung injury

(2011) Min-Yung Kuo et al.   FOOD AND CHEMICAL TOXICOLOGY

Editorial: Neutrophil apoptosis: hot on the TRAIL of inflammatory resolution

(2011) Andrew E. Leitch et al.   JOURNAL OF LEUKOCYTE BIOLOGY

TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation

(2011) Emmet E. McGrath et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Effective Caspase Inhibition Blocks Neutrophil Apoptosis and Reveals Mcl-1 as Both a Regulator and a Target of Neutrophil Caspase Activation

(2011) David J. Wardle et al.   PLoS One

Protective effects of luteolin against lipopolysaccharide-induced acute lung injury involves inhibition of MEK/ERK and PI3K/Akt pathways in neutrophils

(2010) Jen-pei Lee et al.   ACTA PHARMACOLOGICA SINICA

Anti-Inflammatory Benefits of Antibiotic-Induced Neutrophil Apoptosis: Tulathromycin Induces Caspase-3-Dependent Neutrophil Programmed Cell Death and Inhibits NF-κB Signaling and CXCL8 Transcription

(2010) Carrie D. Fischer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Icariin Derivative Inhibits Inflammation through Suppression of p38 Mitogen-Activated Protein Kinase and Nuclear Factor-κB Pathways

(2010) Shao-Rui Chen et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Combining naturally occurring polyphenols with TNF-related apoptosis-inducing ligand: a promising approach to kill resistant cancer cells?

(2010) Guillaume Jacquemin et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The cyclin-dependent kinase inhibitor R-roscovitine down-regulates Mcl-1 to override pro-inflammatory signalling and drive neutrophil apoptosis

(2010) Andrew E. Leitch et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The sphingosine kinase-1 survival pathway is a molecular target for the tumor-suppressive tea and wine polyphenols in prostate cancer

(2010) Leyre Brizuela et al.   FASEB JOURNAL

Intake of grape-derived polyphenols reduces C26 tumor growth by inhibiting angiogenesis and inducing apoptosis

(2010) Allison Walter et al.   FASEB JOURNAL

The dietary flavonoid apigenin blocks phorbol 12-myristate 13-acetate-induced COX-2 transcriptional activity in breast cell lines

(2010) Grace Tak Yi Lau et al.   FOOD AND CHEMICAL TOXICOLOGY

Targeting granulocyte apoptosis: mechanisms, models, and therapies

(2010) Rodger Duffin et al.   IMMUNOLOGICAL REVIEWS

Luteolin Ameliorates Experimental Lung Fibrosis Bothin Vivoandin Vitro: Implications for Therapy of Lung Fibrosis

(2010) Chiu-Yuan Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Natural Flavone Kaempferol Suppresses Chemokines Expression in Human Monocyte THP-1 Cells through MAPK Pathways

(2010) Ching-Hua Huang et al.   JOURNAL OF FOOD SCIENCE

Neutrophil Apoptosis: Relevance to the Innate Immune Response and Inflammatory Disease

(2010) Sarah Fox et al.   Journal of Innate Immunity

The role of defective clearance of apoptotic cells in systemic autoimmunity

(2010) Luis E. Muñoz et al.   Nature Reviews Rheumatology

Flavonoids as anti-inflammatory agents

(2010) Mauro Serafini et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

The p53-Target Gene Puma Drives Neutrophil-Mediated Protection against Lethal Bacterial Sepsis

(2010) Sean P. Garrison et al.   PLoS Pathogens

15-Epi-lipoxin A4Inhibits Myeloperoxidase Signaling and Enhances Resolution of Acute Lung Injury

(2009) Driss El Kebir et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Nobiletin improves brain ischemia-induced learning and memory deficits through stimulation of CaMKII and CREB phosphorylation

(2009) Yui Yamamoto et al.   BRAIN RESEARCH

Multiple Therapeutic Effects of Adjunctive Baicalin Therapy in Experimental Bacterial Meningitis

(2009) Yong-Jun Tang et al.   INFLAMMATION

The Anti-Inflammatory and Proresolving Mediator Resolvin E1 Protects Mice from Bacterial Pneumonia and Acute Lung Injury

(2009) H. Seki et al.   JOURNAL OF IMMUNOLOGY

Pivotal Advance: Pharmacological manipulation of inflammation resolution during spontaneously resolving tissue neutrophilia in the zebrafish

(2009) Catherine A. Loynes et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Apoptosis Is Essential for Neutrophil Functional Shutdown and Determines Tissue Damage in Experimental Pneumococcal Meningitis

(2009) Uwe Koedel et al.   PLoS Pathogens

Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro-inflammatory and anti-inflammatory agents: key role for TNF-α

(2008) Sylwia Michlewska et al.   FASEB JOURNAL

Alveolar macrophage phagocytosis is impaired in children with poorly controlled asthma

(2008) Anne M. Fitzpatrick et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Benefits from Dietary Polyphenols for Brain Aging and Alzheimer’s Disease

(2008) L. Rossi et al.   NEUROCHEMICAL RESEARCH