Autoimmune disease in the epigenetic era: how has epigenetics changed our understanding of disease and how can we expect the field to evolve?
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Autoimmune disease in the epigenetic era: how has epigenetics changed our understanding of disease and how can we expect the field to evolve?
Authors
Keywords
-
Journal
Expert Review of Clinical Immunology
Volume 11, Issue 1, Pages 45-58
Publisher
Informa UK Limited
Online
2014-12-23
DOI
10.1586/1744666x.2015.994507
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- MicroRNA expression profiles of peripheral blood mononuclear cells in patients with systemic lupus erythematosus
- (2014) Dongmei Liu et al. ACTA HISTOCHEMICA
- Increased miR-223 expression in T cells from patients with rheumatoid arthritis leads to decreased insulin-like growth factor-1-mediated interleukin-10 production
- (2014) M.-C. Lu et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Diet, gut microbes, and genetics in immune function: can we leverage our current knowledge to achieve better outcomes in inflammatory bowel diseases?
- (2014) Vanessa A Leone et al. CURRENT OPINION IN IMMUNOLOGY
- Autoantibodies against platelet-derived growth factor receptor alpha in patients with systemic lupus erythematosus
- (2014) Kazuhiro Kurasawa et al. Modern Rheumatology
- Accounting for cellular heterogeneity is critical in epigenome-wide association studies
- (2014) Andrew E Jaffe et al. GENOME BIOLOGY
- Genome-Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Cartilage
- (2014) Matlock A. Jeffries et al. Arthritis & Rheumatology
- The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis
- (2013) Clara Dees et al. ANNALS OF THE RHEUMATIC DISEASES
- The role of miRNA in inflammation and autoimmunity
- (2013) Ram Pyare Singh et al. AUTOIMMUNITY REVIEWS
- DNA hypermethylation leads to lower FOXP3 expression in CD4+ T cells of patients with primary Sjögren's syndrome
- (2013) Xinhai Yu et al. CLINICAL IMMUNOLOGY
- Aberrant histone modification in peripheral blood B cells from patients with systemic sclerosis
- (2013) YaoYao Wang et al. CLINICAL IMMUNOLOGY
- Mammalian DNA demethylation
- (2013) Lars Schomacher Epigenetics
- Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients
- (2013) Patrick Coit et al. JOURNAL OF AUTOIMMUNITY
- Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse
- (2013) Kristi A. Koelsch et al. JOURNAL OF AUTOIMMUNITY
- Epigenetic dysregulation in salivary glands from patients with primary Sjögren's syndrome may be ascribed to infiltrating B cells
- (2013) Yosra Thabet et al. JOURNAL OF AUTOIMMUNITY
- Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression
- (2013) Lorenzo de la Rica et al. JOURNAL OF AUTOIMMUNITY
- The Catalytic Subunit of Protein Phosphatase 2A (PP2Ac) Promotes DNA Hypomethylation by Suppressing the Phosphorylated Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase (ERK) Kinase (MEK)/Phosphorylated ERK/DNMT1 Protein Pathway in T-cells from Controls and Systemic Lupus Erythematosus Patients
- (2013) Katsue Sunahori et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNA-21 in Scleroderma Fibrosis and its Function in TGF-β- Regulated Fibrosis-Related Genes Expression
- (2013) Honglin Zhu et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Regulation of DNA Methylation in Rheumatoid Arthritis Synoviocytes
- (2013) K. Nakano et al. JOURNAL OF IMMUNOLOGY
- Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins
- (2013) Morgan L Maeder et al. NATURE BIOTECHNOLOGY
- Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
- (2013) Yun Liu et al. NATURE BIOTECHNOLOGY
- Oxidative stress in the pathology and treatment of systemic lupus erythematosus
- (2013) Andras Perl Nature Reviews Rheumatology
- Genome-Wide DNA Methylation Analysis of Systemic Lupus Erythematosus Reveals Persistent Hypomethylation of Interferon Genes and Compositional Changes to CD4+ T-cell Populations
- (2013) Devin M. Absher et al. PLoS Genetics
- DNA methylation of distal regulatory sites characterizes dysregulation of cancer genes
- (2013) Dvir Aran et al. GENOME BIOLOGY
- MicroRNA-451 Down-Regulates Neutrophil Chemotaxis via p38 MAPK
- (2013) Koichi Murata et al. Arthritis & Rheumatology
- DNA methylome signature in rheumatoid arthritis
- (2012) Kazuhisa Nakano et al. ANNALS OF THE RHEUMATIC DISEASES
- Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis
- (2012) Marlene Krämer et al. ANNALS OF THE RHEUMATIC DISEASES
- DNA demethylation of CD40L in CD4+ T cells from women with systemic sclerosis: A possible explanation for female susceptibility
- (2012) XiaoRi Lian et al. ARTHRITIS AND RHEUMATISM
- Protein kinase Cδ oxidation contributes to ERK inactivation in lupus T cells
- (2012) Gabriela J. Gorelik et al. ARTHRITIS AND RHEUMATISM
- Tumor necrosis factor-costimulated T lymphocytes from patients with systemic sclerosis trigger collagen production in fibroblasts
- (2012) Thomas Hügle et al. ARTHRITIS AND RHEUMATISM
- Demethylation of TNFSF7 contributes to CD70 overexpression in CD4+ T cells from patients with systemic sclerosis
- (2012) HongYan Jiang et al. CLINICAL IMMUNOLOGY
- CD40L demethylation in CD4+ T cells from women with rheumatoid arthritis
- (2012) J. Liao et al. CLINICAL IMMUNOLOGY
- Genome-scale profiling reveals a subset of genes regulated by DNA methylation that program somatic T-cell phenotypes in humans
- (2012) D Martino et al. GENES AND IMMUNITY
- Cutting Edge: Protein Phosphatase 2A Confers Susceptibility to Autoimmune Disease through an IL-17-Dependent Mechanism
- (2012) J. C. Crispin et al. JOURNAL OF IMMUNOLOGY
- TGF- -Mediated Downregulation of MicroRNA-196a Contributes to the Constitutive Upregulated Type I Collagen Expression in Scleroderma Dermal Fibroblasts
- (2012) N. Honda et al. JOURNAL OF IMMUNOLOGY
- miR-29 Inhibits Bleomycin-induced Pulmonary Fibrosis in Mice
- (2012) Jun Xiao et al. MOLECULAR THERAPY
- Chromatin marks identify critical cell types for fine mapping complex trait variants
- (2012) Gosia Trynka et al. NATURE GENETICS
- microRNA-92a expression in the sera and dermal fibroblasts increases in patients with scleroderma
- (2012) T. Sing et al. RHEUMATOLOGY
- Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis
- (2012) Alfiya Akhmetshina et al. Nature Communications
- Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis
- (2011) Jelena Vojinovic et al. ARTHRITIS AND RHEUMATISM
- Increased recycling of polyamines is associated with global DNA hypomethylation in rheumatoid arthritis synovial fibroblasts
- (2011) Emmanuel Karouzakis et al. ARTHRITIS AND RHEUMATISM
- Phase 1 study of epigenetic priming with decitabine prior to standard induction chemotherapy for patients with AML
- (2011) J. M. Scandura et al. BLOOD
- Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond
- (2011) Junjie U. Guo et al. CELL CYCLE
- Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus
- (2011) Matlock Jeffries et al. Epigenetics
- Altered miR-146a expression in Sjögren's syndrome and its functional role in innate immunity
- (2011) Kaleb M. Pauley et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts
- (2011) E Karouzakis et al. GENES AND IMMUNITY
- Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas Ligand pathway
- (2011) Veerauo V Konkankit et al. Journal of Translational Medicine
- On the Evolutionary Origin of Eukaryotic DNA Methyltransferases and Dnmt2
- (2011) Tomasz P. Jurkowski et al. PLoS One
- Overexpression of the growth arrest and DNA damage-induced 45α gene contributes to autoimmunity by promoting DNA demethylation in lupus T cells
- (2010) Yaping Li et al. ARTHRITIS AND RHEUMATISM
- MicroRNA-29, a key regulator of collagen expression in systemic sclerosis
- (2010) Britta Maurer et al. ARTHRITIS AND RHEUMATISM
- MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1
- (2010) Sha Zhao et al. ARTHRITIS AND RHEUMATISM
- A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer
- (2010) Fang Fang et al. CANCER
- DNA methylome in human CD4+ T cells identifies transcriptionally repressive and non-repressive methylation peaks
- (2010) T Hughes et al. GENES AND IMMUNITY
- Global DNA methylation, DNMT1, and MBD2 in patients with rheumatoid arthritis
- (2010) Ching-Ching Liu et al. IMMUNOLOGY LETTERS
- Toward defining the autoimmune microbiome for type 1 diabetes
- (2010) Adriana Giongo et al. ISME Journal
- Epigenetics and SLE: RFX1 downregulation causes CD11a and CD70 overexpression by altering epigenetic modifications in lupus CD4+ T cells
- (2010) Ming Zhao et al. JOURNAL OF AUTOIMMUNITY
- Hypomethylation and overexpression of CD70 (TNFSF7) in CD4+ T cells of patients with primary Sjögren's syndrome
- (2010) Heng Yin et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- A Role for Lymphotoxin in Primary Sjogren's Disease
- (2010) L. Shen et al. JOURNAL OF IMMUNOLOGY
- Histone Deacetylase Inhibitors Suppress Inflammatory Activation of Rheumatoid Arthritis Patient Synovial Macrophages and Tissue
- (2010) Aleksander M. Grabiec et al. JOURNAL OF IMMUNOLOGY
- MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1
- (2010) W. Pan et al. JOURNAL OF IMMUNOLOGY
- A Proof-of-Principle Demonstration of a Novel Microarray-Based Method for Quantifying DNA Methylation Levels
- (2010) Xiujuan Zhang et al. MOLECULAR BIOTECHNOLOGY
- Perforin level in CD4+ T cells from patients with systemic lupus erythematosus
- (2010) Anna Kozłowska et al. RHEUMATOLOGY INTERNATIONAL
- Altered microRNA expression profile with miR-146a upregulation in CD4+ T cells from patients with rheumatoid arthritis
- (2010) Jingyi Li et al. ARTHRITIS RESEARCH & THERAPY
- Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis
- (2010) Tomoko Kawabata et al. ARTHRITIS RESEARCH & THERAPY
- Histone deacetylase 7, a potential target for the antifibrotic treatment of systemic sclerosis
- (2009) Hossein Hemmatazad et al. ARTHRITIS AND RHEUMATISM
- DNA hypomethylation in rheumatoid arthritis synovial fibroblasts
- (2009) Emmanuel Karouzakis et al. ARTHRITIS AND RHEUMATISM
- T cell CD40LG gene expression and the production of IgG by autologous B cells in systemic lupus erythematosus
- (2009) Ying Zhou et al. CLINICAL IMMUNOLOGY
- Epigenetic Histone Code and Autoimmunity
- (2009) Jürgen Dieker et al. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- Global H4 acetylation analysis by ChIP-chip in systemic lupus erythematosus monocytes
- (2009) Z Zhang et al. GENES AND IMMUNITY
- Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
- (2009) B. M. Javierre et al. GENOME RESEARCH
- The RNA-induced Silencing Complex: A Versatile Gene-silencing Machine
- (2009) Ashley J. Pratt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DNA demethylation of the perforin promoter in CD4+ T cells from patients with subacute cutaneous lupus erythematosus
- (2009) Yongqi Luo et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Requirement for DNA CpG Content in TLR9-Dependent Dendritic Cell Activation Induced by DNA-Containing Immune Complexes
- (2009) K. Yasuda et al. JOURNAL OF IMMUNOLOGY
- Expression and Function of Histone Deacetylases in Rheumatoid Arthritis Synovial Fibroblasts
- (2009) M. HORIUCHI et al. JOURNAL OF RHEUMATOLOGY
- Ultraviolet B exposure of peripheral blood mononuclear cells of patients with systemic lupus erythematosus inhibits DNA methylation
- (2009) GS Wang et al. LUPUS
- Apoptosis-associated acetylation on histone H2B is an epitope for lupus autoantibodies
- (2009) Casandra C. van Bavel et al. MOLECULAR IMMUNOLOGY
- Human DNA methylomes at base resolution show widespread epigenomic differences
- (2009) Ryan Lister et al. NATURE
- A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
- (2009) Vesela Gateva et al. NATURE GENETICS
- Identification of Keratinocyte Growth Factor as a Target of microRNA-155 in Lung Fibroblasts: Implication in Epithelial-Mesenchymal Interactions
- (2009) Nicolas Pottier et al. PLoS One
- Abnormal DNA methylation in CD4+ T cells from patients with systemic lupus erythematosus, systemic sclerosis, and dermatomyositis
- (2009) W Lei et al. SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
- A CD40-CD154 interaction in tissue fibrosis
- (2008) Masataka Kawai et al. ARTHRITIS AND RHEUMATISM
- Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: Support for the notion of a gene-dose effect from the X chromosome
- (2008) R. Hal Scofield et al. ARTHRITIS AND RHEUMATISM
- Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients
- (2008) A H Sawalha et al. GENES AND IMMUNITY
- Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation
- (2008) Yutaka Kondo et al. NATURE GENETICS
- Blockade of CD40/CD40 ligand interactions attenuates skin fibrosis and autoimmunity in the tight-skin mouse
- (2007) K Komura et al. ANNALS OF THE RHEUMATIC DISEASES
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now