The Catalytic Subunit of Protein Phosphatase 2A (PP2Ac) Promotes DNA Hypomethylation by Suppressing the Phosphorylated Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase (ERK) Kinase (MEK)/Phosphorylated ERK/DNMT1 Protein Pathway in T-cells from Controls and Systemic Lupus Erythematosus Patients

PP2A Dephosphorylates Elf-1 and Determines the Expression of CD3  and FcR  in Human Systemic Lupus Erythematosus T Cells

(2014) Y.-T. Juang et al.   JOURNAL OF IMMUNOLOGY

Methylation Status of CpG Islands Flanking a cAMP Response Element Motif on the Protein Phosphatase 2Ac  Promoter Determines CREB Binding and Activity

(2014) K. Sunahori et al.   JOURNAL OF IMMUNOLOGY

DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes

(2012) Eriko G. Clements et al.   NUCLEIC ACIDS RESEARCH

cAMP response element modulator   controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus

(2012) C. M. Hedrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PKC isoforms interact with and phosphorylate DNMT1

(2011) Geneviève Lavoie et al.   BMC BIOLOGY

cAMP-responsive Element Modulator α (CREMα) Suppresses IL-17F Protein Expression in T Lymphocytes from Patients with Systemic Lupus Erythematosus (SLE)

(2011) Christian M. Hedrich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Promoter Hypomethylation Results in Increased Expression of Protein Phosphatase 2A in T Cells from Patients with Systemic Lupus Erythematosus

(2011) Katsue Sunahori et al.   JOURNAL OF IMMUNOLOGY

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Induction of PP2A B , a regulator of IL-2 deprivation-induced T-cell apoptosis, is deficient in systemic lupus erythematosus

(2011) J. C. Crispin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic mechanisms in systemic lupus erythematosus and other autoimmune diseases

(2011) Christian M. Hedrich et al.   TRENDS IN MOLECULAR MEDICINE

RFX1 regulates CD70 and CD11a expression in lupus T cells by recruiting the histone methyltransferase SUV39H1

(2011) Ming Zhao et al.   ARTHRITIS RESEARCH & THERAPY

Abnormalities of T cell signaling in systemic lupus erythematosus

(2011) Vaishali R Moulton et al.   ARTHRITIS RESEARCH & THERAPY

Epigenetic mechanisms in lupus

(2010) Dipak R Patel et al.   CURRENT OPINION IN RHEUMATOLOGY

Transcriptional Activation of the cAMP-responsive Modulator Promoter in Human T Cells Is Regulated by Protein Phosphatase 2A-mediated Dephosphorylation of SP-1 and Reflects Disease Activity in Patients with Systemic Lupus Erythematosus

(2010) Yuang-Taung Juang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypomethylation ofIL10andIL13Promoters in CD4+T Cells of Patients with Systemic Lupus Erythematosus

(2010) Ming Zhao et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

T cells as therapeutic targets in SLE

(2010) José C. Crispín et al.   Nature Reviews Rheumatology

Decreased DNA methyltransferase levels contribute to abnormal gene expression in “senescent” CD4+CD28− T cells

(2009) Ying Liu et al.   CLINICAL IMMUNOLOGY

Aberrant T cell ERK pathway signaling and chromatin structure in lupus

(2008) Gabriela Gorelik et al.   AUTOIMMUNITY REVIEWS