Mast cell activation: A complex interplay of positive and negative signaling pathways

Activation and Function of the mTORC1 Pathway in Mast Cells

(2014) M.-S. Kim et al.   JOURNAL OF IMMUNOLOGY

Molecular Editing of Cellular Responses by the High-Affinity Receptor for IgE

(2014) R. Suzuki et al.   SCIENCE

IgG-mediated down-regulation of IgE bound to mast cells: a potential novel mechanism of allergen-specific desensitization

(2013) C. Uermösi et al.   ALLERGY

Rapid polyclonal desensitization with antibodies to IgE and FcεRIα

(2013) Marat V. Khodoun et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Efficient cytokine-induced IL-13 production by mast cells requires both IL-33 and IL-3

(2013) Ilkka S. Junttila et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Thymic stromal lymphopoietin receptor blockade reduces allergic inflammation in a cynomolgus monkey model of asthma

(2013) Donavan T. Cheng et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Rapid desensitization induces internalization of antigen-specific IgE on mouse mast cells

(2013) Tatsuya Oka et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Diminished allergic disease in patients with STAT3 mutations reveals a role for STAT3 signaling in mast cell degranulation

(2013) Andrea M. Siegel et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Apoptosis of mouse mast cells is reciprocally regulated by the IgG receptors FcγRIIB and FcγRIIIA

(2012) Y. Fang et al.   ALLERGY

Regulation of mast cell survival and function by tuberous sclerosis complex 1

(2012) J. Shin et al.   BLOOD

Properties of mouse and human IgG receptors and their contribution to disease models

(2012) P. Bruhns   BLOOD

Evolutionary functional analysis and molecular regulation of the ZEB transcription factors

(2012) Alexander Gheldof et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Negative control of mast cell degranulation and the anaphylactic response by the phosphatase lipin1

(2012) Jinwook Shin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Syk-dependent regulation of Hrs phosphorylation and ubiquitination upon FcεRI engagement: Impact on Hrs membrane/cytosol localization

(2012) Francesca Gasparrini et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Airway epithelial cells activate TH2 cytokine production in mast cells through IL-1 and thymic stromal lymphopoietin

(2012) Deepti R. Nagarkar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

DJ-1 regulates mast cell activation and IgE-mediated allergic responses

(2012) Do Kyun Kim et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Once Phosphorylated, Tyrosines in Carboxyl Terminus of Protein-tyrosine Kinase Syk Interact with Signaling Proteins, Including TULA-2, a Negative Regulator of Mast Cell Degranulation

(2012) Rodrigo Orlandini de Castro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pak2 Kinase Restrains Mast Cell FcϵRI Receptor Signaling through Modulation of Rho Protein Guanine Nucleotide Exchange Factor (GEF) Activity

(2012) Rachelle Kosoff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lyn but Not Fyn Kinase Controls IgG-Mediated Systemic Anaphylaxis

(2012) Y. T. Falanga et al.   JOURNAL OF IMMUNOLOGY

Inducible IL-33 Expression by Mast Cells Is Regulated by a Calcium-Dependent Pathway

(2012) C.-L. Hsu et al.   JOURNAL OF IMMUNOLOGY

The Transcription Factor Zeb2 Regulates Signaling in Mast Cells

(2012) E. A. Barbu et al.   JOURNAL OF IMMUNOLOGY

The Adaptor 3BP2 Is Required for Early and Late Events in Fc RI Signaling in Human Mast Cells

(2012) E. Ainsua-Enrich et al.   JOURNAL OF IMMUNOLOGY

IL-33 Induces a Hyporesponsive Phenotype in Human and Mouse Mast Cells

(2012) M.-Y. Jung et al.   JOURNAL OF IMMUNOLOGY

Mast cell chymase modulates IL-33 levels and controls allergic sensitization in dust-mite induced airway inflammation

(2012) I Waern et al.   Mucosal Immunology

Shp2 Activates Fyn and Ras to Regulate RBL-2H3 Mast Cell Activation following FcεRI Aggregation

(2012) Xiaoyun Fang et al.   PLoS One

Interleukin-33 Primes Mast Cells for Activation by IgG Immune Complexes

(2012) Shinjiro Kaieda et al.   PLoS One

TSLP Expression: Cellular Sources, Triggers, and Regulatory Mechanisms

(2012) Toshiro Takai   ALLERGOLOGY INTERNATIONAL

Novel Identified Receptors on Mast Cells

(2012) Helena Migalovich-Sheikhet et al.   Frontiers in Immunology

Mast Cell: An Emerging Partner in Immune Interaction

(2012) Giorgia Gri et al.   Frontiers in Immunology

IL-33 induces Th17-mediated airway inflammation via mast cells in ovalbumin-challenged mice

(2011) Kyung-Ah Cho et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Thymic stromal lymphopoietin is expressed and produced by caspase-1/NF-κB pathway in mast cells

(2011) Phil-Dong Moon et al.   CYTOKINE

Amplification of cytokine production through synergistic activation of NFAT and AP-1 following stimulation of mast cells with antigen and IL-33

(2011) Marcus V. Andrade et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Rapid IgE desensitization is antigen specific and impairs early and late mast cell responses targeting FcεRI internalization

(2011) Maria del Carmen Sancho-Serra et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-33 induces skin inflammation with mast cell and neutrophil activation

(2011) Axel J. Hueber et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Association of 3BP2 with SHP-1 regulates SHP-1-mediated production of TNF-α in RBL-2H3 cells

(2011) Kazuyasu Chihara et al.   GENES TO CELLS

IgE induces transcriptional regulation of thymic stromal lymphopoietin in human airway smooth muscle cells

(2011) Naresh Singh Redhu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice

(2011) Katherine Arias et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The Src Family Kinase Fgr Is Critical for Activation of Mast Cells and IgE-Mediated Anaphylaxis in Mice

(2011) J. H. Lee et al.   JOURNAL OF IMMUNOLOGY

Mast cells in allergy and infection: Versatile effector and regulatory cells in innate and adaptive immunity

(2010) Stephen J. Galli et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

PTP  Activates Lyn and Fyn and Suppresses Hck to Negatively Regulate Fc RI-Dependent Mast Cell Activation and Allergic Responses

(2010) L. A. Samayawardhena et al.   JOURNAL OF IMMUNOLOGY

Loss of TRPC1-mediated Ca2+ influx contributes to impaired degranulation in Fyn-deficient mouse bone marrow-derived mast cells

(2010) Ryo Suzuki et al.   JOURNAL OF LEUKOCYTE BIOLOGY

IL-33 Is Produced by Mast Cells and Regulates IgE-Dependent Inflammation

(2010) Chia-Lin Hsu et al.   PLoS One

Resolution of Allergic Inflammation and Airway Hyperreactivity Is Dependent upon Disruption of the T1/ST2–IL-33 Pathway

(2009) Jennifer Kearley et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics

(2009) J. D. Allen et al.   BLOOD

Our perception of the mast cell from Paul Ehrlich to now

(2009) Michael A. Beaven   EUROPEAN JOURNAL OF IMMUNOLOGY

SHP-1 Deficient Mast Cells Are Hyperresponsive to Stimulation and Critical in Initiating Allergic Inflammation in the Lung

(2009) L. Zhang et al.   JOURNAL OF IMMUNOLOGY

Increased Expression of IL-33 in Severe Asthma: Evidence of Expression by Airway Smooth Muscle Cells

(2009) D. Prefontaine et al.   JOURNAL OF IMMUNOLOGY

New developments in mast cell biology

(2008) Janet Kalesnikoff et al.   NATURE IMMUNOLOGY