Chromatin modifications during repair of environmental exposure-induced DNA damage: A potential mechanism for stable epigenetic alterations

The Chromatin Response to DNA Breaks: Leaving a Mark on Genome Integrity

(2013) Godelieve Smeenk et al.   Annual Review of Biochemistry

Chromatin Remodeling at DNA Double-Strand Breaks

(2013) Brendan D. Price et al.   CELL

Polycomb repressive complex 2 contributes to DNA double-strand break repair

(2013) Stuart Campbell et al.   CELL CYCLE

Epigenetic markers of exposure to polycyclic aromatic hydrocarbons in Mexican brickmakers: A pilot study

(2013) Jorge Alejandro Alegría-Torres et al.   CHEMOSPHERE

MicroRNAs in the ionizing radiation response and in radiotherapy

(2013) Chanatip Metheetrairut et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Polycomb complexes in stem cells and embryonic development

(2013) L. Aloia et al.   DEVELOPMENT

Microsomal epoxide hydrolase (EPHX1) polymorphisms are associated with aberrant promoter methylation of ERCC3 and hematotoxicity in benzene-exposed workers

(2013) Caihong Xing et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Assessment of DNA damage in Brazilian workers occupationally exposed to pesticides: a study from Central Brazil

(2013) Carolinne Borges Khayat et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Radiation-induced epigenetic DNA methylation modification of radiation-response pathways

(2013) Deborah A Antwih et al.   Epigenetics

Non-coding RNAs in DNA damage and repair

(2013) Vivek Sharma et al.   FEBS LETTERS

MicroRNAs play a central role in molecular dysfunctions linking inflammation with cancer

(2013) Esmerina Tili et al.   IMMUNOLOGICAL REVIEWS

Epigenetics Meets Radiation Biology as a New Approach in Cancer Treatment

(2013) Joong-Gook Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

microRNA-7 Suppresses the Invasive Potential of Breast Cancer Cells and Sensitizes Cells to DNA Damages by Targeting Histone Methyltransferase SET8

(2013) Na Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic damage in soybean workers exposed to pesticides: Evaluation with the comet and buccal micronucleus cytome assays

(2013) Danieli Benedetti et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Melatonin ameliorates bisphenol A-induced DNA damage in the germ cells of adult male rats

(2013) Hong-Juan Wu et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark

(2013) Amélie Fradet-Turcotte et al.   NATURE

Chromatin proteins and modifications as drug targets

(2013) Kristian Helin et al.   NATURE

Charity begins at home: non-coding RNA functions in DNA repair

(2013) Dipanjan Chowdhury et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination

(2013) Jiangbo Tang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Integrative Analysis of miRNA and Inflammatory Gene Expression After Acute Particulate Matter Exposure

(2013) Valeria Motta et al.   TOXICOLOGICAL SCIENCES

Epigenetics and pesticides

(2013) M. Collotta et al.   TOXICOLOGY

Histone H4 deacetylation facilitates 53BP1 DNA damage signaling and double-strand break repair

(2013) K.-Y. Hsiao et al.   Journal of Molecular Cell Biology

ATM–Dependent MiR-335 Targets CtIP and Modulates the DNA Damage Response

(2013) Nathan T. Martin et al.   PLoS Genetics

At the intersection of non-coding transcription, DNA repair, chromatin structure, and cellular senescence

(2013) Ryosuke Ohsawa et al.   Frontiers in Genetics

Associations between Arsenic Exposure and Global Posttranslational Histone Modifications among Adults in Bangladesh

(2012) Y. Chervona et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

A Role for Small RNAs in DNA Double-Strand Break Repair

(2012) Wei Wei et al.   CELL

Benzo[a]pyrene-Induced Changes in MicroRNA–mRNA Networks

(2012) Daneida Lizarraga et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Accumulation of DNA damage in complex normal tissues after protracted low-dose radiation

(2012) Stefanie Schanz et al.   DNA REPAIR

A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

(2012) Martijn S Luijsterburg et al.   EMBO JOURNAL

Prenatal Exposure to Polycyclic Aromatic Hydrocarbons, Benzo[ a ]pyrene–DNA Adducts, and Genomic DNA Methylation in Cord Blood

(2012) Julie B. Herbstman et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Adaptive radiation-induced epigenetic alterations mitigated by antioxidants

(2012) Autumn J. Bernal et al.   FASEB JOURNAL

The control of histone methylation and gene expression by oxidative stress, hypoxia, and metals

(2012) Yana Chervona et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inflammation-Associated Cancer Development in Digestive Organs: Mechanisms and Roles for Genetic and Epigenetic Modulation

(2012) Tsutomu Chiba et al.   GASTROENTEROLOGY

Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationships

(2012) Victoria K. Cortessis et al.   HUMAN GENETICS

Epigenetic targets of some toxicologically relevant metals: a review of the literature

(2012) Tsu-Fan Cheng et al.   JOURNAL OF APPLIED TOXICOLOGY

Chromodomain Helicase DNA-binding Protein 4 (CHD4) Regulates Homologous Recombination DNA Repair, and Its Deficiency Sensitizes Cells to Poly(ADP-ribose) Polymerase (PARP) Inhibitor Treatment

(2012) Mei-Ren Pan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Poly(ADP-ribosyl)ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling

(2012) G. Smeenk et al.   JOURNAL OF CELL SCIENCE

The emerging role of Polycomb repressors in the response to DNA damage

(2012) Joseph H. A. Vissers et al.   JOURNAL OF CELL SCIENCE

Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer

(2012) Karim Nacerddine et al.   JOURNAL OF CLINICAL INVESTIGATION

Prime, Repair, Restore: The Active Role of Chromatin in the DNA Damage Response

(2012) Gaston Soria et al.   MOLECULAR CELL

Histone H2A.Z Controls a Critical Chromatin Remodeling Step Required for DNA Double-Strand Break Repair

(2012) Ye Xu et al.   MOLECULAR CELL

Clastogenic and mutagenic effects of bisphenol A: An endocrine disruptor

(2012) Dinesh Tiwari et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Site-specific DICER and DROSHA RNA products control the DNA-damage response

(2012) Sofia Francia et al.   NATURE

DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks

(2012) Tibor Pankotai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes

(2012) Eriko G. Clements et al.   NUCLEIC ACIDS RESEARCH

Endocrine Disruptor Regulation of MicroRNA Expression in Breast Carcinoma Cells

(2012) Syreeta L. Tilghman et al.   PLoS One

Urinary Benzene Biomarkers and DNA Methylation in Bulgarian Petrochemical Workers: Study Findings and Comparison of Linear and Beta Regression Models

(2012) Wei Jie Seow et al.   PLoS One

Superconductivity of topological matters induced via pressure

(2012) Jun-liang Zhang et al.   Frontiers of Physics

Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands

(2011) Heather M. O'Hagan et al.   CANCER CELL

Tip60: Connecting chromatin to DNA damage signaling

(2011) Yingli Sun et al.   CELL CYCLE

Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage

(2011) Z Wu et al.   CELL DEATH AND DIFFERENTIATION

Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4

(2011) Doris M. Seiler et al.   CHROMOSOME RESEARCH

Molecular Pathways: Involvement of Helicobacter pylori-Triggered Inflammation in the Formation of an Epigenetic Field Defect, and Its Usefulness as Cancer Risk and Exposure Markers

(2011) T. Ushijima et al.   CLINICAL CANCER RESEARCH

Differential DNA Methylation Alterations in Radiation-Sensitive and -Resistant Cells

(2011) M. Ahmad Chaudhry et al.   DNA AND CELL BIOLOGY

Environmental chemical exposures and human epigenetics

(2011) Lifang Hou et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Monoubiquitination of H2AX Protein Regulates DNA Damage Response Signaling

(2011) Mei-Ren Pan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HP1α recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair

(2011) Céline Baldeyron et al.   JOURNAL OF CELL BIOLOGY

BMI1 Is Recruited to DNA Breaks and Contributes to DNA Damage-Induced H2A Ubiquitination and Repair

(2011) V. Ginjala et al.   MOLECULAR AND CELLULAR BIOLOGY

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

(2011) Claudia Lukas et al.   NATURE CELL BIOLOGY

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

(2011) Jiri Lukas et al.   NATURE CELL BIOLOGY

GADD45α inhibition of DNMT1 dependent DNA methylation during homology directed DNA repair

(2011) Bongyong Lee et al.   NUCLEIC ACIDS RESEARCH

Early-stage formation of an epigenetic field defect in a mouse colitis model and non-essential roles of T- and B-cells in DNA methylation induction

(2011) M Katsurano et al.   ONCOGENE

Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors

(2011) H Ogiwara et al.   ONCOGENE

UVA-induced epigenetic regulation of P16INK4ain human epidermal keratinocytes and skin tumor derived cells

(2011) I-Peng Chen et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

An anticlastogenic function for the Polycomb Group gene Bmi1

(2011) J. Chagraoui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA methylation changes in cells regrowing after fractioned ionizing radiation

(2011) Christine Kuhmann et al.   RADIOTHERAPY AND ONCOLOGY

Pulmonary gene and microRNA expression changes in mice exposed to benzo(a)pyrene by oral gavage

(2011) Sabina Halappanavar et al.   TOXICOLOGY

Oxidative stress and oxidative damage in chemical carcinogenesis

(2011) James E. Klaunig et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Genetic Variants of Nucleotide Excision Repair Genes Are Associated with DNA Damage in Coke Oven Workers

(2010) F. Wang et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Insufficient role of cell proliferation in aberrant DNA methylation induction and involvement of specific types of inflammation

(2010) Keun Hur et al.   CARCINOGENESIS

RETRACTED: Aberrant DNA hypermethylation patterns lead to transcriptional silencing of tumor suppressor genes in UVB-exposed skin and UVB-induced skin tumors of mice

(2010) Vijayalakshmi Nandakumar et al.   CARCINOGENESIS

ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks

(2010) Niraj M. Shanbhag et al.   CELL

Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4

(2010) Sophie E Polo et al.   EMBO JOURNAL

Airborne particulate matter and mitochondrial damage: a cross-sectional study

(2010) Lifang Hou et al.   Environmental Health

Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery

(2010) Kyungsoo Ha et al.   HUMAN MOLECULAR GENETICS

p300-mediated Acetylation of Histone H3 Lysine 56 Functions in DNA Damage Response in Mammals

(2010) Rahul K. Vempati et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair

(2010) Ye Xu et al.   JOURNAL OF CELL BIOLOGY

The NuRD chromatin–remodeling complex regulates signaling and repair of DNA damage

(2010) Godelieve Smeenk et al.   JOURNAL OF CELL BIOLOGY

DNA damage signaling in response to double-strand breaks during mitosis

(2010) Simona Giunta et al.   JOURNAL OF CELL BIOLOGY

The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage

(2010) Dorthe Helena Larsen et al.   JOURNAL OF CELL BIOLOGY

BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair

(2010) Ismail Hassan Ismail et al.   JOURNAL OF CELL BIOLOGY

SIRT1 Regulates UV-Induced DNA Repair through Deacetylating XPA

(2010) Wei Fan et al.   MOLECULAR CELL

Radiation-induced epigenetic alterations after low and high LET irradiations

(2010) Umut Aypar et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

CpG islands influence chromatin structure via the CpG-binding protein Cfp1

(2010) John P. Thomson et al.   NATURE

Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining

(2010) Kyle M Miller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

GCN5 and E2F1 stimulate nucleotide excision repair by promoting H3K9 acetylation at sites of damage

(2010) Ruifeng Guo et al.   NUCLEIC ACIDS RESEARCH

Helicobacter pylori-Induced Histone Modification, Associated Gene Expression in Gastric Epithelial Cells, and Its Implication in Pathogenesis

(2010) Song-Ze Ding et al.   PLoS One

A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

(2010) D. M. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bisphenol A exposure leads to specific microRNA alterations in placental cells

(2010) Michele Avissar-Whiting et al.   REPRODUCTIVE TOXICOLOGY

In Utero Exposure to Diethylstilbestrol (DES) or Bisphenol-A (BPA) Increases EZH2 Expression in the Mammary Gland: An Epigenetic Mechanism Linking Endocrine Disruptors to Breast Cancer

(2010) Leo F. Doherty et al.   Hormones & Cancer

Sirt1 physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX

(2009) Kazutsune Yamagata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evaluation of a suitable DNA damage biomarker for human biomonitoring of exposed workers

(2009) Delia Cavallo et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Global and gene-specific promoter methylation changes are related toanti-B[a]PDE-DNA adduct levels and influence micronuclei levels in polycyclic aromatic hydrocarbon-exposed individuals

(2009) Sofia Pavanello et al.   INTERNATIONAL JOURNAL OF CANCER

Heterochromatin protein 1 is recruited to various types of DNA damage

(2009) Martijn S. Luijsterburg et al.   JOURNAL OF CELL BIOLOGY

Lung Cancer and Chronic Obstructive Pulmonary Disease: Needs and Opportunities for Integrated Research

(2009) A. Punturieri et al.   JNCI-Journal of the National Cancer Institute

The Role of p300 Histone Acetyltransferase in UV-Induced Histone Modifications and MMP-1 Gene Transcription

(2009) Min-Kyoung Kim et al.   PLoS One

Methylation of Polycomb Target Genes in Intestinal Cancer Is Mediated by Inflammation

(2008) M. A. Hahn et al.   CANCER RESEARCH

SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging

(2008) Philipp Oberdoerffer et al.   CELL

Regulation of WRN Protein Cellular Localization and Enzymatic Activities by SIRT1-mediated Deacetylation

(2008) Kai Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Rvb1/Tip49 Is Required for the Histone Acetyltransferase Activity of Tip60/NuA4 and for the Downregulation of Phosphorylation on H2AX after DNA Damage

(2008) S. Jha et al.   MOLECULAR AND CELLULAR BIOLOGY

Biomarkers of oxidative stress and damage in human populations exposed to arsenic

(2008) Andrea De Vizcaya-Ruiz et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell

(2008) Zehui Hong et al.   NUCLEIC ACIDS RESEARCH

Double Strand Breaks Can Initiate Gene Silencing and SIRT1-Dependent Onset of DNA Methylation in an Exogenous Promoter CpG Island

(2008) Heather M. O'Hagan et al.   PLoS Genetics