BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair

Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer

(2010) Li Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Polycomb group protein gene silencing, non-coding RNA, stem cells, and cancerThis paper is one of a selection of papers published in this Special Issue, entitled The 30th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal's usual peer review process.

(2009) Randall S. Gieni et al.   Biochemistry and Cell Biology

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

(2009) Grant S. Stewart et al.   CELL

Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80

(2009) Yusuke Sato et al.   EMBO JOURNAL

Nucleotide excision repair–induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

(2009) Jurgen A. Marteijn et al.   JOURNAL OF CELL BIOLOGY

Bmi1 regulates mitochondrial function and the DNA damage response pathway

(2009) Jie Liu et al.   NATURE

RAD18 promotes DNA double-strand break repair during G1 phase through chromatin retention of 53BP1

(2009) Kenji Watanabe et al.   NUCLEIC ACIDS RESEARCH

The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubc13-dependent ubiquitination events at DNA double strand breaks

(2009) G. Shao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis

(2008) Katherine Minter-Dykhouse et al.   JOURNAL OF CELL BIOLOGY

Noncanonical E2 Variant-Independent Function of UBC13 in Promoting Checkpoint Protein Assembly

(2008) M. S. Y. Huen et al.   MOLECULAR AND CELLULAR BIOLOGY

A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell

(2008) Zehui Hong et al.   NUCLEIC ACIDS RESEARCH

The γ-H2A.X: Is it just a surrogate marker of double-strand breaks or much more?

(2007) Ismail Hassan Ismail et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS