Epigenetic targets of some toxicologically relevant metals: a review of the literature

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers

(2015) Michael Christoph Haffner et al.   Oncotarget

5-Hydroxymethylcytosine, the Sixth Base of the Genome

(2011) Martin Münzel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Differences in the epigenetic regulation of MT-3 gene expression between parental and Cd+2 or As+3 transformed human urothelial cells

(2011) Seema Somji et al.   Cancer Cell International

Epigenetic Changes in Individuals with Arsenicosis

(2011) Lisa Smeester et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Thymine DNA Glycosylase Can Rapidly Excise 5-Formylcytosine and 5-Carboxylcytosine

(2011) Atanu Maiti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Studying the epigenome using next generation sequencing

(2011) C. S. Ku et al.   JOURNAL OF MEDICAL GENETICS

OPERating ON Chromatin, a Colorful Language where Context Matters

(2011) Kathryn E. Gardner et al.   JOURNAL OF MOLECULAR BIOLOGY

Chronic arsenic toxicity: Studies in West Bengal, India

(2011) Debendranath Guha Mazumder et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

Comparative characterization of the PvuRts1I family of restriction enzymes and their application in mapping genomic 5-hydroxymethylcytosine

(2011) Hua Wang et al.   NUCLEIC ACIDS RESEARCH

Genome-wide identification of Medicago truncatula microRNAs and their targets reveals their differential regulation by heavy metal

(2011) ZHAO SHENG ZHOU et al.   PLANT CELL AND ENVIRONMENT

Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

(2011) Y.-F. He et al.   SCIENCE

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

(2011) S. Ito et al.   SCIENCE

Epigenetic Effect of Cadmium on Global De Novo DNA Hypomethylation in the Cadmium-Induced Ventral Body Wall Defect (VBWD) in the Chick Model

(2011) Takashi Doi et al.   TOXICOLOGICAL SCIENCES

Occupational genotoxicity among copper smelters

(2011) Juliana Viégas Duarte De Olivera et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

From Waddington’s epigenetic landscape to small noncoding RNA: some important milestones in the history of epigenetics research

(2011) Supratim Choudhuri   TOXICOLOGY MECHANISMS AND METHODS

Role of epigenetic events in chemical carcinogenesis—a justification for incorporating epigenetic evaluations in cancer risk assessment

(2011) Igor Koturbash et al.   TOXICOLOGY MECHANISMS AND METHODS

Obesogens

(2011) Felix Grün   Current Opinion in Endocrinology Diabetes and Obesity

Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA

(2010) Colm Nestor et al.   BIOTECHNIQUES

Hypoxia and nickel inhibit histone demethylase JMJD1A and repress Spry2 expression in human bronchial epithelial BEAS-2B cells

(2010) Haobin Chen et al.   CARCINOGENESIS

Chromium genotoxicity: A double-edged sword

(2010) Kristen P. Nickens et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Quantitative mass spectrometry reveals the epigenome as a target of arsenic

(2010) Feixia Chu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Coordination of Cu2+and Ni2+ with the histone model peptide of H2B N-terminal tail (1-31 residues): A spectroscopic study

(2010) Ana Mónica Nunes et al.   DALTON TRANSACTIONS

Small noncoding RNAs: Biogenesis, function, and emerging significance in toxicology

(2010) Supratim Choudhuri   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Copper effective binding with 32–62 and 94–125 peptide fragments of histone H2B

(2010) Kimon Zavitsanos et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Aberrant DNA methylation of some tumor suppressor genes in lung cancers from workers with chromate exposure

(2010) Abdellah H. K. Ali et al.   MOLECULAR CARCINOGENESIS

Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine

(2010) Chun-Xiao Song et al.   NATURE BIOTECHNOLOGY

The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing

(2010) Yun Huang et al.   PLoS One

Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates

(2010) Daniel Globisch et al.   PLoS One

Genome-wide Analysis of DNA Methylation and Gene Expression Changes in the Mouse Lung following Subchronic Arsenate Exposure

(2010) Frank Boellmann et al.   TOXICOLOGICAL SCIENCES

Molecular targets of epigenetic regulation and effectors of environmental influences☆☆☆

(2010) Supratim Choudhuri et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

DNA hypomethylation induced by tributyltin, triphenyltin, and a mixture of these in Sebastiscus marmoratus liver

(2009) Yuqing Wang et al.   AQUATIC TOXICOLOGY

Heterochromatinization as a Potential Mechanism of Nickel-Induced Carcinogenesis

(2009) Thomas P. Ellen et al.   BIOCHEMISTRY

Reticulon RTN1-CCTPeptide: A Potential Nuclease and Inhibitor of Histone Deacetylase Enzymes

(2009) Ridvan Nepravishta et al.   BIOCHEMISTRY

Epigenetics and environmental chemicals

(2009) Andrea Baccarelli et al.   CURRENT OPINION IN PEDIATRICS

Pathogenesis, clinical features and pathology of chronic arsenicosis

(2009) NilayKanti Das et al.   Indian Journal of Dermatology Venereology & Leprology

Effects of Mixtures of Polychlorinated Biphenyls, Methylmercury, and Organochlorine Pesticides on Hepatic DNA Methylation in Prepubertal Female Sprague-Dawley Rats

(2009) Daniel Desaulniers et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Nickel Ions Inhibit Histone Demethylase JMJD1A and DNA Repair Enzyme ABH2 by Replacing the Ferrous Iron in the Catalytic Centers

(2009) Haobin Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetics in metal carcinogenesis: nickel, arsenic, chromium and cadmium

(2009) Adriana Arita et al.   Metallomics

Physiological and toxicological transcriptome changes in HepG2 cells exposed to copper

(2009) Min Ok Song et al.   PHYSIOLOGICAL GENOMICS

Does promoter methylation of the SLC30A5 (ZnT5) zinc transporter gene contribute to the ageing-related decline in zinc status?

(2009) L. J. Coneyworth et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE

Involvement of DNA hypermethylation in down-regulation of the zinc transporter ZIP8 in cadmium-resistant metallothionein-null cells

(2009) Hitomi Fujishiro et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Low levels of methylmercury induce DNA damage in rats: protective effects of selenium

(2008) Denise Grotto et al.   ARCHIVES OF TOXICOLOGY

Bioinformatic identification and expression analysis of new microRNAs from Medicago truncatula

(2008) Zhao Sheng Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nucleic Acid Binding of the RTN1-C C-Terminal Region: Toward the Functional Role of a Reticulon Protein†

(2008) Sonia Melino et al.   BIOCHEMISTRY

Nickel compounds induce phosphorylation of histone H3 at serine 10 by activating JNK-MAPK pathway

(2008) Q. Ke et al.   CARCINOGENESIS

Epigenetic silencing of O6 -methylguanine DNA methyltransferase gene in NiS-transformed cells

(2008) Weidong Ji et al.   CARCINOGENESIS

Arsenite alters global histone H3 methylation

(2008) X. Zhou et al.   CARCINOGENESIS

Long-lasting depression-like behavior and epigenetic changes of BDNF gene expression induced by perinatal exposure to methylmercury

(2008) Natalia Onishchenko et al.   JOURNAL OF NEUROCHEMISTRY

Alzheimer's Disease (AD)-Like Pathology in Aged Monkeys after Infantile Exposure to Environmental Metal Lead (Pb): Evidence for a Developmental Origin and Environmental Link for AD

(2008) J. Wu et al.   JOURNAL OF NEUROSCIENCE

Epigenetic interplay between histone modifications and DNA methylation in gene silencing

(2008) T VAISSIERE et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Global DNA hypomethylation, rather than reactive oxygen species (ROS), a potential facilitator of cadmium-stimulated K562 cell proliferation

(2008) Dejun Huang et al.   TOXICOLOGY LETTERS

Genetic and Epigenetic Mechanisms in Metal Carcinogenesis and Cocarcinogenesis: Nickel, Arsenic, and Chromium

(2007) Konstantin Salnikow et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Effects of long-term low-dose cadmium exposure on genomic DNA methylation in human embryo lung fibroblast cells

(2007) Gaofeng Jiang et al.   TOXICOLOGY

Nickel compounds induce histone ubiquitination by inhibiting histone deubiquitinating enzyme activity

(2007) Q KE et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY