The Use of Functional Genomics in Conjunction with Metabolomics forMycobacterium tuberculosisResearch

An Altered Mycobacterium tuberculosis Metabolome Induced bykatGMutations Resulting in Isoniazid Resistance

(2014) Du Toit Loots   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

New sputum metabolite markers implicating adaptations of the host to Mycobacterium tuberculosis, and vice versa

(2013) I. du Preez et al.   TUBERCULOSIS

Upregulation of the Phthiocerol Dimycocerosate Biosynthetic Pathway by Rifampin-Resistant,rpoBMutant Mycobacterium tuberculosis

(2012) Gregory P. Bisson et al.   JOURNAL OF BACTERIOLOGY

A comparison of four sputum pre-extraction preparation methods for identifying and characterising Mycobacterium tuberculosis using GCxGC-TOFMS metabolomics

(2012) Johannes C. Schoeman et al.   JOURNAL OF MICROBIOLOGICAL METHODS

A metabolomics approach to characterise and identify various Mycobacterium species

(2012) Ilse Olivier et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Recent advances in mapping environmental microbial metabolisms through 13C isotopic fingerprints

(2012) J. K.-H. Tang et al.   Journal of the Royal Society Interface

A metabolomics approach exploring the function of the ESX-3 type VII secretion system of M. smegmatis

(2012) Du Toit Loots et al.   Metabolomics

A metabolomics investigation of a hyper- and hypo-virulent phenotype of Beijing lineage M. tuberculosis

(2012) Reinart J. Meissner-Roloff et al.   Metabolomics

Altered Fatty Acid Metabolism Due to Rifampicin-Resistance Conferring Mutations in the rpoB Gene of Mycobacterium tuberculosis: Mapping the Potential of Pharmaco-metabolomics for Global Health and Personalized Medicine

(2012) Ilse du Preez et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Innate Immune Recognition ofMycobacterium tuberculosis

(2011) Johanneke Kleinnijenhuis et al.   Clinical & Developmental Immunology

Mycobacterium tuberculosis and the intimate discourse of a chronic infection

(2011) David G. Russell   IMMUNOLOGICAL REVIEWS

NMR-based plant metabolomics: where do we stand, where do we go?

(2011) Hye Kyong Kim et al.   TRENDS IN BIOTECHNOLOGY

Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier

(2011) Kyu Y. Rhee et al.   TRENDS IN MICROBIOLOGY

Recent advances in deciphering the contribution of Mycobacterium tuberculosis lipids to pathogenesis

(2011) Olivier Neyrolles et al.   TUBERCULOSIS

A Systems Biology Approach to Infectious Disease Research: Innovating the Pathogen-Host Research Paradigm

(2011) A. Aderem et al.   mBio

Fumarate Reductase Activity Maintains an Energized Membrane in Anaerobic Mycobacterium tuberculosis

(2011) Shinya Watanabe et al.   PLoS Pathogens

Biotin biosynthesis in Mycobacterium tuberculosis: physiology, biochemistry and molecular intervention

(2011) Wanisa Salaemae et al.   Protein & Cell

Activity-Based Metabolomic Profiling of Enzymatic Function: Identification of Rv1248c as a Mycobacterial 2-Hydroxy-3-oxoadipate Synthase

(2010) Luiz Pedro S. de Carvalho et al.   CHEMISTRY & BIOLOGY

Metabolomics of Mycobacterium tuberculosis Reveals Compartmentalized Co-Catabolism of Carbon Substrates

(2010) Luiz Pedro S. de Carvalho et al.   CHEMISTRY & BIOLOGY

Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis

(2010) José A Caminero et al.   LANCET INFECTIOUS DISEASES

Carbon flux rerouting during Mycobacterium tuberculosis growth arrest

(2010) Lanbo Shi et al.   MOLECULAR MICROBIOLOGY

Branched tricarboxylic acid metabolism in Plasmodium falciparum

(2010) Kellen L. Olszewski et al.   NATURE

Portrait of a Pathogen: The Mycobacterium tuberculosis Proteome In Vivo

(2010) Nicole A. Kruh et al.   PLoS One

Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection

(2010) J. Marrero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel targets in M. tuberculosis: search for new drugs

(2010) Gyanu Lamichhane   TRENDS IN MOLECULAR MEDICINE

Tuberculosis: Pathophysiology, Clinical Features, and Diagnosis

(2009) N. A. Knechel   Critical Care Nurse

ESX/type VII secretion systems and their role in host–pathogen interaction

(2009) Roxane Simeone et al.   CURRENT OPINION IN MICROBIOLOGY

Characterization of a Mycobacterium tuberculosis ESX-3 Conditional Mutant: Essentiality and Rescue by Iron and Zinc

(2009) A. Serafini et al.   JOURNAL OF BACTERIOLOGY

The roles of the nitrate reductase NarGHJI, the nitrite reductase NirBD and the response regulator GlnR in nitrate assimilation of Mycobacterium tuberculosis

(2009) S. Malm et al.   MICROBIOLOGY-SGM

Mycobacterial PE, PPE and ESX clusters: novel insights into the secretion of these most unusual protein families

(2009) Daria Bottai et al.   MOLECULAR MICROBIOLOGY

PPE and PE_PGRS proteins ofMycobacterium marinumare transported via the type VII secretion system ESX-5

(2009) Abdallah M. Abdallah et al.   MOLECULAR MICROBIOLOGY

Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition

(2009) M. S. Siegrist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of pyrazinamidase activity on pyrazinamide resistance in Mycobacterium tuberculosis

(2009) Patricia Sheen et al.   TUBERCULOSIS

The Key Role of Genomics in Modern Vaccine and Drug Design for Emerging Infectious Diseases

(2009) Kate L. Seib et al.   PLoS Genetics

Mycobacterium bovis BCG Vaccine Strains Lack narK2 and narX Induction and Exhibit Altered Phenotypes during Dormancy

(2008) R. W. Honaker et al.   INFECTION AND IMMUNITY

Synergism between natural products and antibiotics against infectious diseases

(2008) Shanmugam Hemaiswarya et al.   PHYTOMEDICINE