Article
Medicine, General & Internal
Maria Chaparro, Ana Garre, Andrea Nunez Ortiz, Maria Teresa Diz-Lois Palomares, Cristina Rodriguez, Sabino Riestra, Milagros Vela, Jose Manuel Benitez, Estela Fernandez Salgado, Eugenia Sanchez Rodriguez, Vicent Hernandez, Rocio Ferreiro-Iglesias, Angel Ponferrada Diaz, Jesus Barrio, Jose Maria Huguet, Beatriz Sicilia, Maria Dolores Martin-Arranz, Xavier Calvet, Daniel Ginard, Inmaculada Alonso-Abreu, Luis Fernandez-Salazar, Pilar Varela Trastoy, Montserrat Rivero, Isabel Vera-Mendoza, Pablo Vega, Pablo Navarro, Monica Sierra, Jose Luis Cabriada, Mariam Aguas, Raquel Vicente, Merce Navarro-Llavat, Ana Echarri, Fernando Gomollon, Elena Guerra del Rio, Concepcion Pinero, Maria Jose Casanova, Katerina Spicakova, Jone Ortiz de Zarate, Emilio Torrella Cortes, Ana Gutierrez, Horacio Alonso-Galan, Alvaro Hernandez-Martinez, Jose Miguel Marrero, Rufo Lorente Poyatos, Margalida Calafat, Lidia Marti Romero, Pilar Robledo, Orencio Bosch, Nuria Jimenez, Maria Esteve Comas, Jose Maria Duque, Ana Maria Fuentes Coronel, Manuela Josefa Sampedro, Eva Sese Abizanda, Belen Herreros Martinez, Liliana Pozzati, Hipolito Fernandez Rosaenz, Belen Crespo Suarez, Pilar Lopez Serrano, Alfredo J. Lucendo, Margarita Munoz Vicente, Fernando Bermejo, Jose Joaquin Ramirez Palanca, Margarita Menacho, Amalia Carmona, Raquel Camargo, Sandra Torra Alsina, Nuria Maroto, Juan Nerin de la Puerta, Elena Castro, Ignacio Marin-Jimenez, Belen Botella, Amparo Sapina, Noelia Cruz, Jose Luis F. Forcelledo, Abdel Bouhmidi, Carlos Castano-Milla, Veronica Opio, Isabel Nicolas, Marcos Kutz, Alfredo Abraldes Bechiarelli, Jordi Gordillo, Yolanda Ber, Yolanda Torres Dominguez, Maria Teresa Novella Duran, Silvia Rodriguez Mondejar, Francisco J. Martinez-Cerezo, Lilyan Kolle, Miriam Sabat, Cesar Ledezma, Eduardo Iyo, Oscar Roncero, Rebeca Irisarri, Laia Lluis, Isabel Blazquez Gomez, Eva Maria Zapata, Maria Jose Alcala, Cristina Martinez Pascual, Maria Montealegre, Laura Mata, Ana Monrobel, Alejandro Hernandez Camba, Luis Hernandez, Maria Tejada, Alberto Mir, Maria Luisa Galve, Marta Soler, Daniel Hervias, Jose Antonio Gomez-Valero, Manuel Barreiro-de Acosta, Fernando Rodriguez-Artalejo, Esther Garcia-Esquinas, Javier P. Gisbert
Summary: The study found a high incidence of inflammatory bowel disease (IBD) in Spain, similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, especially in cases of Crohn's disease (CD) and in hospitals with high resources, which are much higher than previously reported.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Gastroenterology & Hepatology
Emir Tulumovic, Nermin Salkic, Denijal Tulumovic
Summary: A study was conducted to review the epidemiology of inflammatory bowel disease (IBD) in the Tuzla Canton of Bosnia-Herzegovina over a 10-year period. The findings showed that trends in the incidence and prevalence of IBD in the region were similar to Eastern European averages, although there were significant epidemiological differences within geographically close and demographically similar areas.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Review
Biochemistry & Molecular Biology
Vishal Khatri, Ramaswamy Kalyanasundaram
Summary: This review focuses on the association between IBD and gut inflammasome, as well as recent advances in research and therapeutic strategies for IBD, discussing inflammasomes and their components, outcomes from experimental animals and human studies, inflammasome inhibitors, and developments in inflammasome-targeted therapies for IBD.
Review
Biochemistry & Molecular Biology
HyunTaek Jung, Jae Seok Kim, Keum Hwa Lee, Kalthoum Tizaoui, Salvatore Terrazzino, Sarah Cargnin, Lee Smith, Ai Koyanagi, Louis Jacob, Han Li, Sung Hwi Hong, Dong Keon Yon, Seung Won Lee, Min Seo Kim, Paul Wasuwanich, Wikrom Karnsakul, Jae Il Shin, Andreas Kronbichler
Summary: Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract that mainly affects young people. Recent studies have shown that microRNAs (miRNAs) play an important role in the pathogenesis, diagnosis, and treatment of IBD.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Article
Medicine, General & Internal
Rahma Elmahdi, Camilla E. Lemser, Sandra B. Thomsen, Kristine H. Allin, Manasi Agrawal, Tine Jess
Summary: This meta-analysis revealed that patients with pediatric-onset IBD have a more than 2-fold increased rate of cancer compared to the general pediatric population, primarily due to an increased rate of gastrointestinal cancers.
Article
Gastroenterology & Hepatology
Emily W. Lopes, Simon S. M. Chan, Mingyang Song, Jonas F. Ludvigsson, Niclas Hakansson, Paul Lochhead, Allan Clark, Kristin E. Burke, Ashwin N. Ananthakrishnan, Amanda J. Cross, Domenico Palli, Manuela M. Bergmann, James M. Richter, Andrew T. Chan, Ola Olen, Alicja Wolk, Hamed Khalili
Summary: This study aimed to estimate the proportion of cases of Crohn's disease (CD) and ulcerative colitis (UC) that could be prevented by modifiable lifestyle factors. Using several cohorts in the US and Europe, the researchers created modifiable risk scores and healthy lifestyle scores, and found that a significant number of CD and UC cases could be prevented through lifestyle modification.
Article
Gastroenterology & Hepatology
Edward L. Barnes, William B. Nowell, Shilpa Venkatachalam, Angela Dobes, Michael D. Kappelman
Summary: A study found that the prevalence of Crohn's disease and ulcerative colitis is lower among minority populations in the United States.
INFLAMMATORY BOWEL DISEASES
(2022)
Review
Gastroenterology & Hepatology
Manasi Agrawal, Tine Jess
Summary: The epidemiology of inflammatory bowel disease is undergoing changes, with rising incidence and burden of disease. Understanding the causes and preparing healthcare systems are crucial for improving outcomes and health.
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
(2022)
Article
Gastroenterology & Hepatology
Uma Mahadevan, Millie D. Long, Sunanda Kane, Abhik Roy, Marla C. Dubinsky, Bruce E. Sands, Russell D. Cohen, Christina D. Chambers, William J. Sandborn
Summary: The study found that exposure to biologic, thiopurine, or combination therapy during pregnancy did not increase adverse maternal or fetal outcomes, and these treatments can be continued throughout pregnancy for women with IBD to maintain disease control.
Article
Medicine, General & Internal
Silvia Salvatori, Francesco Baldassarre, Michelangela Mossa, Giovanni Monteleone
Summary: Long COVID is common in patients with inflammatory bowel diseases (IBD), with fatigue being the most frequent symptom. It does not influence the frequency of IBD relapses, but is more prevalent in female patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Environmental Sciences
Paul Lochhead, Hamed Khalili, Ashwin N. Ananthakrishnan, Kristin E. Burke, James M. Richter, Qi Sun, Philippe Grandjean, Andrew T. Chan
Summary: The study found inverse associations between certain PFAS concentrations and the risk of Crohn's disease, but no associations with ulcerative colitis risk. This suggests that elevated PFAS exposure may not be associated with higher risk of ulcerative colitis, and some PFAS concentrations may be inversely related to the development of Crohn's disease.
ENVIRONMENTAL RESEARCH
(2022)
Review
Gastroenterology & Hepatology
Thomas M. Goodsall, Tran M. Nguyen, Claire E. Parker, Christopher Ma, Jane M. Andrews, Vipul Jairath, Robert Bryant
Summary: The study systematically identified ultrasound scoring indices for assessing inflammatory bowel disease activity, with common components including bowel wall thickness, colour Doppler imaging, and bowel wall stratification. The correlation between ultrasound indices and reference standards, as well as sensitivity, specificity, accuracy, and other properties, varied within certain ranges. However, reliability and responsiveness data were limited, and most studies were rated with unclear or high risk of bias.
JOURNAL OF CROHNS & COLITIS
(2021)
Review
Medicine, General & Internal
Katarzyna Akutko, Andrzej Stawarski
Summary: Inflammatory bowel diseases (IBD) are chronic inflammatory diseases of the digestive tract with periods of remission and relapses. The etiopathogenesis is not fully understood, leading to only symptomatic treatment. There is a constant need to search for new high safety profile therapies for IBD.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Biotechnology & Applied Microbiology
Guihua Chen, Jun Shen
Summary: Inflammatory bowel disease (IBD) is a global disease with high morbidity and medical costs. Early diagnosis and intervention are crucial for controlling its progression.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Gastroenterology & Hepatology
Jurij Hanzel, Peter Bossuyt, Valerie Pittet, Mark Samaan, Monika Tripathi, Wladyslawa Czuber-Dochan, Johan Burisch, Salvatore Leone, Roberto Saldana, Filip Baert, Uri Kopylov, Susanna Jaghult, Michel Adamina, Naila Arebi, Krisztina Gecse
Summary: This study aimed to develop a core outcome set for real-world studies in adult patients with inflammatory bowel disease (IBD). Candidate outcomes and outcome measures were identified through a systematic review and a modified Delphi consensus process. The international panel agreed on the final core outcome set, which will facilitate the synthesis and generation of real-world evidence.
JOURNAL OF CROHNS & COLITIS
(2023)