IL-17A increases the expression of proinflammatory chemokines in human pancreatic islets

Reduction of Circulating Neutrophils Precedes and Accompanies Type 1 Diabetes

(2013) A. Valle et al.   DIABETES

Candidate genes for type 1 diabetes modulate pancreatic islet inflammation andβ-cell apoptosis

(2013) I. Santin et al.   DIABETES OBESITY & METABOLISM

Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse

(2013) G. Kuriya et al.   DIABETOLOGIA

Cellular Self-Defense: How Cell-Autonomous Immunity Protects Against Pathogens

(2013) F. Randow et al.   SCIENCE

GLIS3, a Susceptibility Gene for Type 1 and Type 2 Diabetes, Modulates Pancreatic Beta Cell Apoptosis via Regulation of a Splice Variant of the BH3-Only Protein Bim

(2013) Tatiane C. Nogueira et al.   PLoS Genetics

Effect of IL-17A blockade with secukinumab in autoimmune diseases

(2012) Dhavalkumar D Patel et al.   ANNALS OF THE RHEUMATIC DISEASES

Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression

(2012) R. Bergholdt et al.   DIABETES

Signalling danger: endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation

(2012) D. L. Eizirik et al.   DIABETOLOGIA

Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes

(2012) I. Marhfour et al.   DIABETOLOGIA

The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α

(2012) Shu Zhu et al.   NATURE MEDICINE

The Transcription Factor C/EBP delta Has Anti-Apoptotic and Anti-Inflammatory Roles in Pancreatic Beta Cells

(2012) Fabrice Moore et al.   PLoS One

Pancreatic islet expression of chemokine CCL2 suppresses autoimmune diabetes via tolerogenic CD11c+ CD11b+ dendritic cells

(2012) M. A. Kriegel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines

(2012) Décio L. Eizirik et al.   PLoS Genetics

Diabetogenic T lymphocytes in human Type 1 diabetes

(2011) Bart O Roep et al.   CURRENT OPINION IN IMMUNOLOGY

Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated  -Cell Death

(2011) S. Arif et al.   DIABETES

Expression and Regulation of Chemokines in Murine and Human Type 1 Diabetes

(2011) S. A. Sarkar et al.   DIABETES

Expansion of Th17 Cells and Functional Defects in T Regulatory Cells Are Key Features of the Pancreatic Lymph Nodes in Patients With Type 1 Diabetes

(2011) Alessandra Ferraro et al.   DIABETES

A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion

(2011) Philippe Ravassard et al.   JOURNAL OF CLINICAL INVESTIGATION

Islet inflammation and CXCL10 in recent-onset type 1 diabetes

(2010) B. O. Roep et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

STAT1 Is a Master Regulator of Pancreatic β-Cell Apoptosis and Islet Inflammation

(2010) Fabrice Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-17 Immunity in Human Type 1 Diabetes

(2010) J. Honkanen et al.   JOURNAL OF IMMUNOLOGY

Genetics, pathogenesis and clinical interventions in type 1 diabetes

(2010) Jeffrey A. Bluestone et al.   NATURE

Translational Mini-Review Series on Th17 Cells: Function and regulation of human T helper 17 cells in health and disease

(2009) S. Q. Crome et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Cytokines Interleukin-1  and Tumor Necrosis Factor-  Regulate Different Transcriptional and Alternative Splicing Networks in Primary  -Cells

(2009) F. Ortis et al.   DIABETES

Inhibition of Th17 Cells Regulates Autoimmune Diabetes in NOD Mice

(2009) J. A. Emamaullee et al.   DIABETES

PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon- -Induced Pancreatic  -Cell Apoptosis

(2009) F. Moore et al.   DIABETES

Interferon regulatory factor-1 is a key transcription factor in murine beta cells under immune attack

(2009) C. Gysemans et al.   DIABETOLOGIA

Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells

(2009) Natalia Martin-Orozco et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The role of inflammation in insulitis and β-cell loss in type 1 diabetes

(2009) Décio L. Eizirik et al.   Nature Reviews Endocrinology

Increased Expression of CCL2 in Insulin-Producing Cells of Transgenic Mice Promotes Mobilization of Myeloid Cells From the Bone Marrow, Marked Insulitis, and Diabetes

(2008) A. P. Martin et al.   DIABETES