Regeneration versus scarring in vertebrate appendages and heart

Osteoblast de- and redifferentiation are controlled by a dynamic response to retinoic acid during zebrafish fin regeneration

(2015) N. Blum et al.   DEVELOPMENT

Control of tissue growth by Yap relies on cell density and F-actin in zebrafish fin regeneration

(2015) R. Mateus et al.   DEVELOPMENT

Retinoic acid signaling spatially restricts osteoblasts and controls ray-interray organization during zebrafish fin regeneration

(2015) N. Blum et al.   DEVELOPMENT

A dual epimorphic and compensatory mode of heart regeneration in zebrafish

(2015) Pauline Sallin et al.   DEVELOPMENTAL BIOLOGY

Recent advances in the study of zebrafish extracellular matrix proteins

(2015) Jason R. Jessen   DEVELOPMENTAL BIOLOGY

Nerves Regulate Cardiomyocyte Proliferation and Heart Regeneration

(2015) Ahmed I. Mahmoud et al.   DEVELOPMENTAL CELL

Timing of cardiomyocyte growth, maturation, and attrition in perinatal sheep

(2015) Sonnet S. Jonker et al.   FASEB JOURNAL

Bone morphogenetic protein signaling promotes morphogenesis of blood vessels, wound epidermis, and actinotrichia during fin regeneration in zebrafish

(2015) Valentine Thorimbert et al.   FASEB JOURNAL

Epicardial regeneration is guided by cardiac outflow tract and Hedgehog signalling

(2015) Jinhu Wang et al.   NATURE

Signaling networks organizing regenerative growth of the zebrafish fin

(2015) Daniel Wehner et al.   TRENDS IN GENETICS

Turning terminally differentiated skeletal muscle cells into regenerative progenitors

(2015) Heng Wang et al.   Nature Communications

Developmental alterations in centrosome integrity contribute to the post-mitotic state of mammalian cardiomyocytes

(2015) David C Zebrowski et al.   eLife

Nrg1 is an injury-induced cardiomyocyte mitogen for the endogenous heart regeneration program in zebrafish

(2015) Matthew Gemberling et al.   eLife

Mechanisms underlying vertebrate limb regeneration: lessons from the salamander

(2014) Jeremy P. Brockes et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Specific NuRD components are required for fin regeneration in zebrafish

(2014) Catherine Pfefferli et al.   BMC BIOLOGY

Denervation impairs regeneration of amputated zebrafish fins

(2014) Mariana G Simões et al.   BMC DEVELOPMENTAL BIOLOGY

Rethinking Differentiation: Stem Cells, Regeneration, and Plasticity

(2014) Alejandro Sánchez Alvarado et al.   CELL

Hand2 elevates cardiomyocyte production during zebrafish heart development and regeneration

(2014) Y. L. Schindler et al.   DEVELOPMENT

Keeping at Arm’s Length during Regeneration

(2014) Valerie A. Tornini et al.   DEVELOPMENTAL CELL

Differential reparative phenotypes between zebrafish and medaka after cardiac injury

(2014) Kohei Ito et al.   DEVELOPMENTAL DYNAMICS

Scar-free wound healing and regeneration in amphibians: Immunological influences on regenerative success

(2014) James W. Godwin et al.   DIFFERENTIATION

Understanding positional cues in salamander limb regeneration: implications for optimizing cell-based regenerative therapies

(2014) C. D. McCusker et al.   Disease Models & Mechanisms

The epicardium signals the way towards heart regeneration

(2014) Megan Masters et al.   Stem Cell Research

Advances in understanding the mechanism of zebrafish heart regeneration

(2014) Kazu Kikuchi   Stem Cell Research

Sequential and Opposing Activities of Wnt and BMP Coordinate Zebrafish Bone Regeneration

(2014) Scott Stewart et al.   Cell Reports

Wnt/β-Catenin Signaling Defines Organizing Centers that Orchestrate Growth and Differentiation of the Regenerating Zebrafish Caudal Fin

(2014) Daniel Wehner et al.   Cell Reports

A molecular and genetic outline of cardiac morphogenesis

(2013) M. S. Rana et al.   Acta Physiologica

A blueprint for engineering cell fate: current technologies to reprogram cell identity

(2013) Samantha A Morris et al.   CELL RESEARCH

Fundamental Differences in Dedifferentiation and Stem Cell Recruitment during Skeletal Muscle Regeneration in Two Salamander Species

(2013) Tatiana Sandoval-Guzmán et al.   Cell Stem Cell

Remodeling and dedifferentiation of adult cardiomyocytes during disease and regeneration

(2013) Marten Szibor et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Connective tissue cells, but not muscle cells, are involved in establishing the proximo-distal outcome of limb regeneration in the axolotl

(2013) E. Nacu et al.   DEVELOPMENT

A dynamic spatiotemporal extracellular matrix facilitates epicardial-mediated vertebrate heart regeneration

(2013) Sarah E. Mercer et al.   DEVELOPMENTAL BIOLOGY

Fibronectin is deposited by injury-activated epicardial cells and is necessary for zebrafish heart regeneration

(2013) Jinhu Wang et al.   DEVELOPMENTAL BIOLOGY

Adult Zebrafish as a Model System for Cutaneous Wound-Healing Research

(2013) Rebecca Richardson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

In vivo cardiac reprogramming contributes to zebrafish heart regeneration

(2013) Ruilin Zhang et al.   NATURE

Wnt activation in nail epithelium couples nail growth to digit regeneration

(2013) Makoto Takeo et al.   NATURE

Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair

(2013) Mei Xin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cardiomyocyte proliferation contributes to heart growth in young humans

(2013) Mariya Mollova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstitution of the Myocardium in Regenerating Newt Hearts is Preceded by Transient Deposition of Extracellular Matrix Components

(2013) Tanja Piatkowski et al.   STEM CELLS AND DEVELOPMENT

The zebrafish as a model for complex tissue regeneration

(2013) Matthew Gemberling et al.   TRENDS IN GENETICS

Detrimental dermal wound healing: What can we learn from the oral mucosa?

(2013) Judith E. Glim et al.   WOUND REPAIR AND REGENERATION

Cardiac Regenerative Capacity and Mechanisms

(2012) Kazu Kikuchi et al.   Annual Review of Cell and Developmental Biology

Tenascin-C in Cardiovascular Tissue Remodeling

(2012) Kyoko Imanaka-Yoshida   CIRCULATION JOURNAL

Migration of cardiomyocytes is essential for heart regeneration in zebrafish

(2012) J. Itou et al.   DEVELOPMENT

The regenerative capacity of the zebrafish heart is dependent on TGF  signaling

(2012) F. Chablais et al.   DEVELOPMENT

Limited dedifferentiation provides replacement tissue during zebrafish fin regeneration

(2012) Scott Stewart et al.   DEVELOPMENTAL BIOLOGY

Regulation of zebrafish heart regeneration by miR-133

(2012) Viravuth P. Yin et al.   DEVELOPMENTAL BIOLOGY

Regeneration of Amputated Zebrafish Fin Rays from De Novo Osteoblasts

(2012) Sumeet Pal Singh et al.   DEVELOPMENTAL CELL

The myofibroblast matrix: implications for tissue repair and fibrosis

(2012) Franco Klingberg et al.   JOURNAL OF PATHOLOGY

Functional screening identifies miRNAs inducing cardiac regeneration

(2012) Ana Eulalio et al.   NATURE

Skin shedding and tissue regeneration in African spiny mice (Acomys)

(2012) Ashley W. Seifert et al.   NATURE

Mammalian heart renewal by pre-existing cardiomyocytes

(2012) Samuel E. Senyo et al.   NATURE

Cryoinjury as a myocardial infarction model for the study of cardiac regeneration in the zebrafish

(2012) Juan Manuel González-Rosa et al.   Nature Protocols

Matricellular Proteins in Cardiac Adaptation and Disease

(2012) Nikolaos G. Frangogiannis   PHYSIOLOGICAL REVIEWS

Skin Regeneration in Adult Axolotls: A Blueprint for Scar-Free Healing in Vertebrates

(2012) Ashley W. Seifert et al.   PLoS One

Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family

(2012) E. R. Porrello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nerve dependence in tissue, organ, and appendage regeneration

(2012) Anoop Kumar et al.   TRENDS IN NEUROSCIENCES

Heart repair and regeneration: Recent insights from zebrafish studies

(2012) Ching-Ling Lien et al.   WOUND REPAIR AND REGENERATION

Limb regeneration

(2012) András Simon et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Induction of Myocardial Infarction in Adult Zebrafish Using Cryoinjury

(2012) Fabian Chablais et al.   Jove-Journal of Visualized Experiments

The influence of fundamental traits on mechanisms controlling appendage regeneration

(2011) Ashley W. Seifert et al.   BIOLOGICAL REVIEWS

The zebrafish heart regenerates after cryoinjury-induced myocardial infarction

(2011) Fabian Chablais et al.   BMC DEVELOPMENTAL BIOLOGY

Oncostatin M Is a Major Mediator of Cardiomyocyte Dedifferentiation and Remodeling

(2011) Thomas Kubin et al.   Cell Stem Cell

The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion

(2011) Jinhu Wang et al.   DEVELOPMENT

tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration

(2011) K. Kikuchi et al.   DEVELOPMENT

Differentiated skeletal cells contribute to blastema formation during zebrafish fin regeneration

(2011) S. Sousa et al.   DEVELOPMENT

Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafish

(2011) J. M. Gonzalez-Rosa et al.   DEVELOPMENT

Recapitulation of developmental cardiogenesis governs the morphological and functional regeneration of adult newt hearts following injury

(2011) Nevin Witman et al.   DEVELOPMENTAL BIOLOGY

Bone Regenerates via Dedifferentiation of Osteoblasts in the Zebrafish Fin

(2011) Franziska Knopf et al.   DEVELOPMENTAL CELL

Fate Restriction in the Growing and Regenerating Zebrafish Fin

(2011) Shu Tu et al.   DEVELOPMENTAL CELL

The Cellular Basis for Animal Regeneration

(2011) Elly M. Tanaka et al.   DEVELOPMENTAL CELL

Retinoic Acid Production by Endocardium and Epicardium Is an Injury Response Essential for Zebrafish Heart Regeneration

(2011) Kazu Kikuchi et al.   DEVELOPMENTAL CELL

Looking proximally and distally: 100 years of limb regeneration and beyond

(2011) David L. Stocum et al.   DEVELOPMENTAL DYNAMICS

Adult mouse epicardium modulates myocardial injury by secreting paracrine factors

(2011) Bin Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Heart regeneration

(2011) Michael A. Laflamme et al.   NATURE

Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration

(2011) Chris Jopling et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regeneration of Cryoinjury Induced Necrotic Heart Lesions in Zebrafish Is Associated with Epicardial Activation and Cardiomyocyte Proliferation

(2011) Kristin Schnabel et al.   PLoS One

The structure and function of cardiac t-tubules in health and disease

(2011) M. Ibrahim et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

Calcium handling in zebrafish ventricular myocytes

(2010) Ping-Cheng Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Return to the fetal gene program

(2010) Heinrich Taegtmeyer et al.   Annals of the New York Academy of Sciences

Transcriptomics approach to investigate zebrafish heart regeneration

(2010) Eduard Sleep et al.   Journal of Cardiovascular Medicine

Skin wound healing in axolotls: a scarless process

(2010) Mathieu Lévesque et al.   JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION

Cell plasticity in homeostasis and regeneration

(2010) Brigitte Galliot et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Primary contribution to zebrafish heart regeneration by gata4 + cardiomyocytes

(2010) Kazu Kikuchi et al.   NATURE

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

(2010) Chris Jopling et al.   NATURE

Advances in understanding tissue regenerative capacity and mechanisms in animals

(2010) Kenneth D. Poss   NATURE REVIEWS GENETICS

PDGF signaling is required for epicardial function and blood vessel formation in regenerating zebrafish hearts

(2010) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuregulin1/ErbB4 Signaling Induces Cardiomyocyte Proliferation and Repair of Heart Injury

(2009) Kevin Bersell et al.   CELL

Cardiac Fibroblasts Regulate Myocardial Proliferation through β1 Integrin Signaling

(2009) Masaki Ieda et al.   DEVELOPMENTAL CELL

From fish to amphibians to mammals: in search of novel strategies to optimize cardiac regeneration

(2009) Simonetta Ausoni et al.   JOURNAL OF CELL BIOLOGY

Translational lessons from scarless healing of cutaneous wounds and regenerative repair of the myocardium

(2009) Joseph A. Palatinus et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The extracellular matrix: At the center of it all

(2009) Stephanie L.K. Bowers et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The extracellular matrix as a modulator of the inflammatory and reparative response following myocardial infarction

(2009) Marcin Dobaczewski et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cells keep a memory of their tissue origin during axolotl limb regeneration

(2009) Martin Kragl et al.   NATURE

Myocardial remodeling after infarction: the role of myofibroblasts

(2009) Susanne W. M. van den Borne et al.   Nature Reviews Cardiology

Cardiac fibroblasts: At the heart of myocardial remodeling

(2009) Karen E. Porter et al.   PHARMACOLOGY & THERAPEUTICS

Evidence for Cardiomyocyte Renewal in Humans

(2009) Olaf Bergmann et al.   SCIENCE

Evolution of animal regeneration: re-emergence of a field

(2009) Alexandra E. Bely et al.   TRENDS IN ECOLOGY & EVOLUTION

Characterization of isolated ventricular myocytes from adult zebrafish (Danio rerio)

(2008) Fabien Brette et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nitroreductase-mediated cell/tissue ablation in zebrafish: a spatially and temporally controlled ablation method with applications in developmental and regeneration studies

(2008) Silvia Curado et al.   Nature Protocols

Retinoic acid in development: towards an integrated view

(2008) Karen Niederreither et al.   NATURE REVIEWS GENETICS