Understanding human fetal pancreas development using subpopulation sorting, RNA sequencing and single-cell profiling

The molecular and morphogenetic basis of pancreas organogenesis

(2017) Hjalte List Larsen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors

(2017) Kathryn F. Cogger et al.   Nature Communications

Efficient Generation of Glucose-Responsive Beta Cells from Isolated GP2 + Human Pancreatic Progenitors

(2017) Jacqueline Ameri et al.   Cell Reports

Reconstructing human pancreatic differentiation by mapping specific cell populations during development

(2017) Cyrille Ramond et al.   eLife

Single-Cell Gene Expression Analysis of a Human ESC Model of Pancreatic Endocrine Development Reveals Different Paths to β-Cell Differentiation

(2017) Maja Borup Kjær Petersen et al.   Stem Cell Reports

Laser Capture and Deep Sequencing Reveals the Transcriptomic Programmes Regulating the Onset of Pancreas and Liver Differentiation in Human Embryos

(2017) Rachel E. Jennings et al.   Stem Cell Reports

Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes

(2016) Zengrong Zhu et al.   Cell Stem Cell

The quest to make fully functional human pancreatic beta cells from embryonic stem cells: climbing a mountain in the clouds

(2016) James D. Johnson   DIABETOLOGIA

The genetic architecture of type 2 diabetes

(2016) Christian Fuchsberger et al.   NATURE

g:Profiler—a web server for functional interpretation of gene lists (2016 update)

(2016) Jüri Reimand et al.   NUCLEIC ACIDS RESEARCH

Generation of a Conditional Allele of the Transcription Factor Atonal Homolog 8 (Atoh8)

(2016) Miriam Ejarque et al.   PLoS One

Insights into islet development and biology through characterization of a human iPSC-derived endocrine pancreas model

(2016) Martijn van de Bunt et al.   Islets

Hematopoietic stem cells: concepts, definitions, and the new reality

(2015) C. J. Eaves   BLOOD

Human pancreas development

(2015) R. E. Jennings et al.   DEVELOPMENT

Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development

(2015) Solomon Afelik et al.   DEVELOPMENTAL BIOLOGY

The Basic Helix-Loop-Helix Transcription Factor NEUROG3 Is Required for Development of the Human Endocrine Pancreas

(2015) Patrick S. McGrath et al.   DIABETES

Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

(2015) H. A. Russ et al.   EMBO JOURNAL

TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors

(2015) Inês Cebola et al.   NATURE CELL BIOLOGY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Transcription factor regulation of pancreatic organogenesis, differentiation and maturation

(2015) Reshmi Dassaye et al.   Islets

Efficient Generation of NKX6-1+ Pancreatic Progenitors from Multiple Human Pluripotent Stem Cell Lines

(2015) M. Cristina Nostro et al.   Stem Cell Reports

Generation of Functional Human Pancreatic β Cells In Vitro

(2014) Felicia W. Pagliuca et al.   CELL

Systematically labeling developmental stage-specific genes for the study of pancreatic β-cell differentiation from human embryonic stem cells

(2014) Haisong Liu et al.   CELL RESEARCH

Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3

(2014) A. B. Osipovich et al.   DEVELOPMENT

Distinct requirements for beta-catenin in pancreatic epithelial growth and patterning

(2014) Brett K. Baumgartner et al.   DEVELOPMENTAL BIOLOGY

Development of a conditionally immortalized human pancreatic β cell line

(2014) Raphaël Scharfmann et al.   JOURNAL OF CLINICAL INVESTIGATION

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

(2014) Alireza Rezania et al.   NATURE BIOTECHNOLOGY

The window period of NEUROGENIN3 during human gestation

(2014) Rachel J Salisbury et al.   Islets

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish

(2013) Lydie C Flasse et al.   BMC BIOLOGY

GDNF is required for neural colonization of the pancreas

(2013) J. L. Munoz-Bravo et al.   DEVELOPMENT

Mouse Muscle As an Ectopic Permissive Site for Human Pancreatic Development

(2013) C. Capito et al.   DIABETES

Development of the Human Pancreas From Foregut to Endocrine Commitment

(2013) R. E. Jennings et al.   DIABETES

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas

(2012) K. M. Petzold et al.   DEVELOPMENT

Multiobjective evolutionary algorithms to identify highly autocorrelated areas: the case of spatial distribution in financially compromised farms

(2011) Carlos R. García-Alonso et al.   ANNALS OF OPERATIONS RESEARCH

Pancreas organogenesis: From bud to plexus to gland

(2011) Fong Cheng Pan et al.   DEVELOPMENTAL DYNAMICS

Permanent Neonatal Diabetes and Enteric Anendocrinosis Associated With Biallelic Mutations in NEUROG3

(2011) O. Rubio-Cabezas et al.   DIABETES

Immunohistochemical characterisation of cells co-producing insulin and glucagon in the developing human pancreas

(2011) M. J. Riedel et al.   DIABETOLOGIA

MafA and MafB Regulate Genes Critical to  -Cells in a Unique Temporal Manner

(2010) I. Artner et al.   DIABETES

Pancreatic Exocrine Duct Cells Give Rise to Insulin-Producing β Cells during Embryogenesis but Not after Birth

(2009) Myriam Solar et al.   DEVELOPMENTAL CELL

Endocrine Cell Clustering During Human Pancreas Development

(2009) Jongmin Jeon et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Transcription factor expression in the developing human fetal endocrine pancreas

(2008) B. M. Lyttle et al.   DIABETOLOGIA

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

Pancreatitis and Calcium Signalling

(2008) Robert Sutton et al.   PANCREAS

Activin B receptor ALK7 is a negative regulator of pancreatic  -cell function

(2008) P. Bertolino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA