SDF1–CXCR4 signaling contributes to persistent pain and hypersensitivity via regulating excitability of primary nociceptive neurons: involvement of ERK-dependent Nav1.8 up-regulation

Human Nav1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons

(2015) Chongyang Han et al.   JOURNAL OF NEUROPHYSIOLOGY

PKC–NF-κB are involved in CCL2-induced Nav1.8 expression and channel function in dorsal root ganglion neurons

(2014) Rui Zhao et al.   BIOSCIENCE REPORTS

Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2

(2014) De-Li Cao et al.   EXPERIMENTAL NEUROLOGY

Functional up-regulation of Nav1.8 sodium channel in Aβ afferent fibers subjected to chronic peripheral inflammation

(2014) Mounir Belkouch et al.   Journal of Neuroinflammation

RETRACTED ARTICLE: CXCR4 Signaling Induced Epithelial-Mesenchymal Transition by PI3K/AKT and ERK Pathways in Glioblastoma

(2014) Baoyu Lv et al.   MOLECULAR NEUROBIOLOGY

CXCR4 Chemokine Receptor Signaling Mediates Pain in Diabetic Neuropathy

(2014) Daniela Maria Menichella et al.   Molecular Pain

Emerging targets in neuroinflammation-driven chronic pain

(2014) Ru-Rong Ji et al.   NATURE REVIEWS DRUG DISCOVERY

Interleukin-10 down-regulates voltage gated sodium channels in rat dorsal root ganglion neurons

(2013) Kai-Feng Shen et al.   EXPERIMENTAL NEUROLOGY

The CXCL12/CXCR4/CXCR7 ligand-receptor system regulates neuro-glio-vascular interactions and vessel growth during human brain development

(2013) Daniela Virgintino et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Protein Kinase B/Akt Is Required for Complete Freund's Adjuvant-Induced Upregulation of Nav1.7 and Nav1.8 in Primary Sensory Neurons

(2013) Lingli Liang et al.   JOURNAL OF PAIN

Blockade of Nav1.8 Currents in Nociceptive Trigeminal Neurons Contributes to Anti-trigeminovascular Nociceptive Effect of Amitriptyline

(2013) Jingyao Liang et al.   NEUROMOLECULAR MEDICINE

Wound-healing growth factor, basic FGF, induces Erk1/2-dependent mechanical hyperalgesia

(2013) Christine Andres et al.   PAIN

Fractalkine mediates inflammatory pain through activation of satellite glial cells

(2013) G. R. Souza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Current status of chemokines in the adult CNS

(2013) Annabelle Réaux-Le Goazigo et al.   PROGRESS IN NEUROBIOLOGY

Cellular and subcellular localization of CXCL12 and CXCR4 in rat nociceptive structures: physiological relevance

(2012) Annabelle Reaux-Le Goazigo et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

CC chemokine ligand 2 upregulates the current density and expression of TRPV1 channels and Nav1.8 sodium channels in dorsal root ganglion neurons

(2012) Der-Jang Kao et al.   Journal of Neuroinflammation

Activation of Tetrodotoxin-Resistant Sodium Channel NaV1.9 in Rat Primary Sensory Neurons Contributes to Melittin-Induced Pain Behavior

(2012) Yao-Qing Yu et al.   NEUROMOLECULAR MEDICINE

The Differential Effect of Intrathecal Nav1.8 Blockers on the Induction and Maintenance of Capsaicin- and Peripheral Ischemia-Induced Mechanical Allodynia and Thermal Hyperalgesia

(2011) Ji-Young Moon et al.   ANESTHESIA AND ANALGESIA

Melittin activates TRPV1 receptors in primary nociceptive sensory neurons via the phospholipase A2 cascade pathways

(2011) Yi-Ru Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Chemokine CCL2 Increases Nav1.8 Sodium Channel Activity in Primary Sensory Neurons through a G  -Dependent Mechanism

(2011) M. Belkouch et al.   JOURNAL OF NEUROSCIENCE

Spatiotemporal CCR1, CCL3(MIP-1α), CXCR4, CXCL12(SDF-1α) expression patterns in a rat spinal cord injury model of posttraumatic neuropathic pain

(2011) Friederike Knerlich-Lukoschus et al.   JOURNAL OF NEUROSURGERY-SPINE

The Roles of Sodium Channels in Nociception: Implications for Mechanisms of Neuropathic Pain

(2011) Min Liu et al.   PAIN MEDICINE

Antisense-Mediated Knockdown of NaV1.8, but Not NaV1.9, Generates Inhibitory Effects on Complete Freund's Adjuvant-Induced Inflammatory Pain in Rat

(2011) Yao-Qing Yu et al.   PLoS One

Sodium Channels in Normal and Pathological Pain

(2010) Sulayman D. Dib-Hajj et al.   Annual Review of Neuroscience

CXCR4 signaling mediates morphine-induced tactile hyperalgesia

(2010) Natalie M. Wilson et al.   BRAIN BEHAVIOR AND IMMUNITY

Spatio-temporal changes of SDF1 and its CXCR4 receptor in the dorsal root ganglia following unilateral sciatic nerve injury as a model of neuropathic pain

(2010) Petr Dubový et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Recommendations for the Pharmacological Management of Neuropathic Pain: An Overview and Literature Update

(2010) Robert H. Dworkin et al.   MAYO CLINIC PROCEEDINGS

TNF-α contributes to up-regulation of Nav1.3 and Nav1.8 in DRG neurons following motor fiber injury

(2010) Xin-Hua He et al.   PAIN

The nociceptive and anti-nociceptive effects of bee venom injection and therapy: A double-edged sword

(2010) Jun Chen et al.   PROGRESS IN NEUROBIOLOGY

SDF-1α/CXCR4-mediated migration of systemically transplanted bone marrow stromal cells towards ischemic brain lesion in a rat model

(2008) Ye Wang et al.   BRAIN RESEARCH

Voltage-gated sodium channels in pain states: Role in pathophysiology and targets for treatment

(2008) Sulayman D. Dib-Hajj et al.   BRAIN RESEARCH REVIEWS

Chemokine Network in the Nervous System: A New Target for Pain Relief

(2008) R. Gosselin et al.   CURRENT MEDICINAL CHEMISTRY

Chemokines as pain mediators and modulators

(2008) Fletcher A White et al.   Current Opinion in Anesthesiology

Voltage-gated sodium channels: the search for subtype-selective analgesics

(2008) Steve England   EXPERT OPINION ON INVESTIGATIONAL DRUGS

SDF1α/CXCR4 Signaling, via ERKs and the Transcription Factor Egr1, Induces Expression of a 67-kDa Form of Glutamic Acid Decarboxylase in Embryonic Hippocampal Neurons

(2008) Yongquan Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Chemokine CXCL1/Growth Related Oncogene Increases Sodium Currents and Neuronal Excitability in Small Diameter Sensory Neurons

(2008) Jun-Gang Wang et al.   Molecular Pain

Roles of peripheral mitogen-activated protein kinases in melittin-induced nociception and hyperalgesia

(2008) J. Hao et al.   NEUROSCIENCE

The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain

(2008) B. Abrahamsen et al.   SCIENCE

Multiple roles of chemokine CXCL12 in the central nervous system: A migration from immunology to neurobiology

(2007) M LI et al.   PROGRESS IN NEUROBIOLOGY