Functional up-regulation of Nav1.8 sodium channel in Aβ afferent fibers subjected to chronic peripheral inflammation

Excitability of Aβ sensory neurons is altered in an animal model of peripheral neuropathy

(2012) Yong Zhu et al.   BMC NEUROSCIENCE

Voltage-Gated Sodium Channel Blockers for the Treatment of Chronic Pain

(2012) Mark Matulenko et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Evoked bursting in injured Aβ dorsal root ganglion neurons: A mechanism underlying tactile allodynia

(2012) Ying Song et al.   PAIN

Nav1.8 expression is not restricted to nociceptors in mouse peripheral nervous system

(2012) Shannon D. Shields et al.   PAIN

Involvement of Nav 1.8 sodium ion channels in the transduction of mechanical pain in a rodent model of osteoarthritis

(2012) Niklas Schuelert et al.   ARTHRITIS RESEARCH & THERAPY

The Differential Effect of Intrathecal Nav1.8 Blockers on the Induction and Maintenance of Capsaicin- and Peripheral Ischemia-Induced Mechanical Allodynia and Thermal Hyperalgesia

(2011) Ji-Young Moon et al.   ANESTHESIA AND ANALGESIA

Imaging studies in Freund's complete adjuvant model of regional polyarthritis, a model suitable for the study of pain mechanisms, in the rat

(2011) Lina Almarestani et al.   ARTHRITIS AND RHEUMATISM

Relationship of Axonal Voltage-gated Sodium Channel 1.8 (NaV1.8) mRNA Accumulation to Sciatic Nerve Injury-induced Painful Neuropathy in Rats

(2011) Supanigar Ruangsri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Chemokine CCL2 Increases Nav1.8 Sodium Channel Activity in Primary Sensory Neurons through a G  -Dependent Mechanism

(2011) M. Belkouch et al.   JOURNAL OF NEUROSCIENCE

Effects of prostaglandin D2 on tetrodotoxin-resistant Na+ currents in DRG neurons of adult rat

(2011) Andrea Ebersberger et al.   PAIN

Weight bearing evaluation in inflammatory, neuropathic and cancer chronic pain in freely moving rats

(2011) Pascal Tétreault et al.   PHYSIOLOGY & BEHAVIOR

Antisense-Mediated Knockdown of NaV1.8, but Not NaV1.9, Generates Inhibitory Effects on Complete Freund's Adjuvant-Induced Inflammatory Pain in Rat

(2011) Yao-Qing Yu et al.   PLoS One

Sodium Channels in Normal and Pathological Pain

(2010) Sulayman D. Dib-Hajj et al.   Annual Review of Neuroscience

Bilateral downregulation of Nav1.8 in dorsal root ganglia of rats with bone cancer pain induced by inoculation with Walker 256 breast tumor cells

(2010) Xue-Rong Miao et al.   BMC CANCER

Block of sensory neuronal Na+ channels by the secreolytic ambroxol is associated with an interaction with local anesthetic binding sites

(2010) Andreas Leffler et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Single-cell analysis of sodium channel expression in dorsal root ganglion neurons

(2010) Cojen Ho et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Changes in Aβ Non-Nociceptive Primary Sensory Neurons in a Rat Model of Osteoarthritis Pain

(2010) Qi Wu et al.   Molecular Pain

Central mechanisms of pathological pain

(2010) Rohini Kuner   NATURE MEDICINE

Neuronal circuitry for pain processing in the dorsal horn

(2010) Andrew J. Todd   NATURE REVIEWS NEUROSCIENCE

The trafficking of NaV1.8

(2010) Richard S. Swanwick et al.   NEUROSCIENCE LETTERS

Ranolazine Attenuation of CFA-induced Mechanical Hyperalgesia

(2010) Gregory P. Casey et al.   PAIN MEDICINE

Sodium channelopathies and pain

(2010) Angelika Lampert et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Antinociceptive effect of ambroxol in rats with neuropathic spinal cord injury pain

(2010) Aldric T. Hama et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

PKC∊-Dependent Potentiation of TTX-Resistant NaV1.8 Current by Neurokinin-1 Receptor Activation in Rat Dorsal Root Ganglion Neurons

(2009) Chun-Lei Cang et al.   Molecular Pain

Increased Peripheral Nerve Excitability and Local Nav1.8 RNA Up-Regulation in Painful Neuropathy

(2009) Devang Kashyap Thakor et al.   Molecular Pain

Prostaglandin E2Promotes Nav1.8 Trafficking via Its Intracellular RRR Motif Through the Protein Kinase A Pathway

(2009) Chao Liu et al.   TRAFFIC

Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas

(2008) Joel A. Black et al.   ANNALS OF NEUROLOGY

Ambroxol: A CNS Drug?

(2008) Thomas Weiser   CNS Neuroscience & Therapeutics

Comparative study of the distribution of the α-subunits of voltage-gated sodium channels in normal and axotomized rat dorsal root ganglion neurons

(2008) Tetsuo Fukuoka et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Discovery and Biological Evaluation of 5-Aryl-2-furfuramides, Potent and Selective Blockers of the Nav1.8 Sodium Channel with Efficacy in Models of Neuropathic and Inflammatory Pain

(2008) Michael E. Kort et al.   JOURNAL OF MEDICINAL CHEMISTRY

Characterization of a Model of Chronic Orofacial Hyperalgesia in the Rat: Contribution of NAV 1.8

(2008) James R. Morgan et al.   JOURNAL OF PAIN

Additive Antinociceptive Effects of the Selective Nav1.8 Blocker A-803467 and Selective TRPV1 Antagonists in Rat Inflammatory and Neuropathic Pain Models

(2008) S.K. Joshi et al.   JOURNAL OF PAIN

The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain

(2008) B. Abrahamsen et al.   SCIENCE

Changes in the expression of NaV1.7, NaV1.8 and NaV1.9 in a distinct population of dorsal root ganglia innervating the rat knee joint in a model of chronic inflammatory joint pain

(2007) Iain T. Strickland et al.   EUROPEAN JOURNAL OF PAIN