The Clinical Significance of Posttranslational Modification of Autoantigens

Testing for Gluten-Related Disorders in Clinical Practice: The Role of Serology in Managing the Spectrum of Gluten Sensitivity

(2016) David Armstrong et al.   CANADIAN JOURNAL OF GASTROENTEROLOGY

Serum concentration of immunoglobulin G-type antibodies against the whole Epstein-Barr nuclear antigen 1 and its aa35-58 or aa398-404 fragments in the sera of patients with systemic lupus erythematosus and multiple sclerosis

(2013) D. Csuka et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

New learnings on the pathophysiology of RA from synovial biopsies

(2013) Costantino Pitzalis et al.   CURRENT OPINION IN RHEUMATOLOGY

A subset of anti-rotavirus antibodies directed against the viral protein VP7 predicts the onset of celiac disease and induces typical features of the disease in the intestinal epithelial cell line T84

(2013) Marzia Dolcino et al.   IMMUNOLOGIC RESEARCH

Environment and primary biliary cirrhosis: Electrophilic drugs and the induction of AMA

(2013) Patrick S.C. Leung et al.   JOURNAL OF AUTOIMMUNITY

Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition

(2013) Khaled Amara et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Pathogenesis of the Antiphospholipid Syndrome

(2013) Bill Giannakopoulos et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protein carbamylation: In vivo modification or in vitro artefact?

(2013) Laxmikanth Kollipara et al.   PROTEOMICS

NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

(2013) R. Khandpur et al.   Science Translational Medicine

Nonhuman primate models for Epstein-Barr virus infection

(2013) Fred Wang   Current Opinion in Virology

Recognition of citrullinated and carbamylated proteins by human antibodies: specificity, cross-reactivity and the ‘AMC-Senshu’ method

(2012) Jing Shi et al.   ANNALS OF THE RHEUMATIC DISEASES

Brief Report: Anti-Carbamylated Protein Antibodies Are Present in Arthralgia Patients and Predict the Development of Rheumatoid Arthritis

(2012) Jing Shi et al.   ARTHRITIS AND RHEUMATISM

Autoimmunity to isomerized histone H2B in systemic lupus erythematosus

(2012) Hester A. Doyle et al.   AUTOIMMUNITY

The pathogenesis of systemic lupus erythematosus—an update

(2012) Jinyoung Choi et al.   CURRENT OPINION IN IMMUNOLOGY

Lupus and Epstein-Barr

(2012) Judith A. James et al.   CURRENT OPINION IN RHEUMATOLOGY

Altered posttranslational modification on U1 small nuclear ribonucleoprotein 68k in systemic autoimmune diseases detected by 2D Western blot

(2012) Kouhei Nagai et al.   ELECTROPHORESIS

Characterization of the Phosphoproteome in SLE Patients

(2012) Xinzhou Zhang et al.   PLoS One

Celiac disease: quantity matters

(2012) Frits Koning   Seminars in Immunopathology

From genome-wide association studies to disease mechanisms: celiac disease as a model for autoimmune diseases

(2012) Vinod Kumar et al.   Seminars in Immunopathology

Celiac disease: Management of persistent symptoms in patients on a gluten-free diet

(2012) David H Dewar   WORLD JOURNAL OF GASTROENTEROLOGY

Epigenetic contributions in the development of rheumatoid arthritis

(2012) Kerstin Klein et al.   ARTHRITIS RESEARCH & THERAPY

Expression and function of EZH2 in synovial fibroblasts: epigenetic repression of the Wnt inhibitor SFRP1 in rheumatoid arthritis

(2011) M. Trenkmann et al.   ANNALS OF THE RHEUMATIC DISEASES

Novel assays of thrombogenic pathogenicity in the antiphospholipid syndrome based on the detection of molecular oxidative modification of the major autoantigen β2-glycoprotein I

(2011) Yiannis Ioannou et al.   ARTHRITIS AND RHEUMATISM

Molecular Mimicry as a Mechanism of Autoimmune Disease

(2011) Matthew F. Cusick et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Celiac disease and transglutaminase 2: a model for posttranslational modification of antigens and HLA association in the pathogenesis of autoimmune disorders

(2011) Ludvig M Sollid et al.   CURRENT OPINION IN IMMUNOLOGY

Autoantigenesis: the evolution of protein modifications in autoimmune disease

(2011) Hester A Doyle et al.   CURRENT OPINION IN IMMUNOLOGY

Electrophile-modified lipoic derivatives of PDC-E2 elicits anti-mitochondrial antibody reactivity

(2011) Phornnop Naiyanetr et al.   JOURNAL OF AUTOIMMUNITY

Posttranslational Modification of Gluten Shapes TCR Usage in Celiac Disease

(2011) S.-W. Qiao et al.   JOURNAL OF IMMUNOLOGY

Molecular pathophysiology of the antiphospholipid syndrome: the role of oxidative post-translational modification of beta 2 glycoprotein I

(2011) F. H. PASSAM et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Primary biliary cirrhosis

(2011) Carlo Selmi et al.   LANCET

Antibodies Elicited in Response to EBNA-1 May Cross-React with dsDNA

(2011) Pragya Yadav et al.   PLoS One

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis

(2010) L. Padyukov et al.   ANNALS OF THE RHEUMATIC DISEASES

 2-Glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome

(2010) C. Agar et al.   BLOOD

Recognition of synthetic peptides of Sm-D autoantigen by lupus sera

(2010) S. BARAKAT et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Autoantibody frequency in celiac disease

(2010) Erkan Caglar et al.   Clinics

B-cell epitopes of the intracellular autoantigens Ro/SSA and La/SSB: Tools to study the regulation of the autoimmune response

(2010) John G. Routsias et al.   JOURNAL OF AUTOIMMUNITY

Carbamylation-Dependent Activation of T Cells: A Novel Mechanism in the Pathogenesis of Autoimmune Arthritis

(2010) P. Mydel et al.   JOURNAL OF IMMUNOLOGY

Solution Structure and Characterisation of the Human Pyruvate Dehydrogenase Complex Core Assembly

(2010) S. Vijayakrishnan et al.   JOURNAL OF MOLECULAR BIOLOGY

Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins

(2010) Katleen Van Steendam et al.   ARTHRITIS RESEARCH & THERAPY

Histone deacetylases in RA: epigenetics and epiphenomena

(2010) Aleksander M Grabiec et al.   ARTHRITIS RESEARCH & THERAPY

New Insights into the Biology and Pathobiology of Beta2-Glycoprotein I

(2010) Bill Giannakopoulos et al.   Current Rheumatology Reports

Aberrant Epstein–Barr viral infection in systemic lupus erythematosus

(2009) Brian D. Poole et al.   AUTOIMMUNITY REVIEWS

Rheumatoid arthritis, Proteus, anti-CCP antibodies and Karl Popper

(2009) Alan Ebringer et al.   AUTOIMMUNITY REVIEWS

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

(2009) Zhibin Wang et al.   CELL

Vascular Abnormalities, Paraoxonase Activity, and Dysfunctional HDL in Primary Antiphospholipid Syndrome

(2009) Marietta Charakida   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

(2009) Yanming Wang et al.   JOURNAL OF CELL BIOLOGY

Infections and autoimmunity: the multifaceted relationship

(2009) P. Sfriso et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Glycopeptide profiling of beta-2-glycoprotein I by mass spectrometry reveals attenuated sialylation in patients with antiphospholipid syndrome

(2009) Akira Kondo et al.   Journal of Proteomics

Rheumatoid arthritis

(2009) Lars Klareskog et al.   LANCET

Apoptosis-associated acetylation on histone H2B is an epitope for lupus autoantibodies

(2009) Casandra C. van Bavel et al.   MOLECULAR IMMUNOLOGY

Synovial fibroblasts spread rheumatoid arthritis to unaffected joints

(2009) Stephanie Lefèvre et al.   NATURE MEDICINE

Antibody against mutated citrullinated vimentin: a new sensitive marker in the diagnosis of rheumatoid arthritis

(2009) Ernst Wagner et al.   RHEUMATOLOGY INTERNATIONAL

The role of resident synovial cells in destructive arthritis

(2008) Caroline Ospelt et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Primary sequence, together with other factors, influence peptide deimination by peptidylarginine deiminase-4

(2008) Maria E. Stensland et al.   BIOLOGICAL CHEMISTRY

A Possible Link between Infection with Burkholderia Bacteria and Systemic Lupus Erythematosus Based on Epitope Mimicry

(2008) Wei Zhang et al.   Clinical & Developmental Immunology

Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease

(2008) Kanji Wakabayashi et al.   HEPATOLOGY

Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease

(2008) Deborah J. Smyth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger

(2008) B. A. Croker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antiphospholipid Antibodies and the Antiphospholipid Syndrome: Pathogenic Mechanisms

(2008) Silvia Pierangeli et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Current insight into diagnostics and pathophysiology of the antiphospolipid syndrome

(2007) Rolf T. Urbanus et al.   BLOOD REVIEWS