Molecular pathophysiology of the antiphospholipid syndrome: the role of oxidative post-translational modification of beta 2 glycoprotein I

Novel assays of thrombogenic pathogenicity in the antiphospholipid syndrome based on the detection of molecular oxidative modification of the major autoantigen β2-glycoprotein I

(2011) Yiannis Ioannou et al.   ARTHRITIS AND RHEUMATISM

 2-glycoprotein-1 autoantibodies from patients with antiphospholipid syndrome are sufficient to potentiate arterial thrombus formation in a mouse model

(2011) A. Arad et al.   BLOOD

 2-Glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome

(2010) C. Agar et al.   BLOOD

Beta 2 glycoprotein I is a substrate of thiol oxidoreductases

(2010) F. H. Passam et al.   BLOOD

Naturally occurring free thiols within  2-glycoprotein I in vivo: nitrosylation, redox modification by endothelial cells, and regulation of oxidative stress-induced cell injury

(2010) Y. Ioannou et al.   BLOOD

Oxidative stress enhances AP-1 and NF-κB-mediated regulation of β2-Glycoprotein I gene expression in hepatoma cells

(2010) Wen-Chin Chiu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Redox control of β2-glycoprotein I-von Willebrand factor interaction by thioredoxin-1

(2010) F. H. PASSAM et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Antiphospholipid syndrome

(2010) Guillermo Ruiz-Irastorza et al.   LANCET

New Insights into the Biology and Pathobiology of Beta2-Glycoprotein I

(2010) Bill Giannakopoulos et al.   Current Rheumatology Reports

Antiphospholipid antibodies and risk of myocardial infarction and ischaemic stroke in young women in the RATIO study: a case-control study

(2009) Rolf T Urbanus et al.   LANCET NEUROLOGY

Morbidity and mortality in the antiphospholipid syndrome during a 5-year period: a multicentre prospective study of 1000 patients

(2008) R Cervera et al.   ANNALS OF THE RHEUMATIC DISEASES

Redox Control of Platelet Function

(2008) David W. Essex   ANTIOXIDANTS & REDOX SIGNALING

Autoimmune-mediated atherothrombosis

(2008) E Matsuura et al.   LUPUS

Thrombophilia testing in patients with venous thromboembolism. Findings from the RIETE registry

(2008) Vanessa Roldan et al.   THROMBOSIS RESEARCH