Mechanical regulation of epigenetics in vascular biology and pathobiology

DNA Methylation and Its Basic Function

(2012) Lisa D Moore et al.   NEUROPSYCHOPHARMACOLOGY

Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow

(2012) D.-Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-130a Mediates Proliferation of Vascular Smooth Muscle Cells in Hypertension

(2011) W.-H. Wu et al.   AMERICAN JOURNAL OF HYPERTENSION

MicroRNA-663 upregulated by oscillatory shear stress plays a role in inflammatory response of endothelial cells

(2011) Chih-Wen Ni et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Suppression of Histone Deacetylases Worsens Right Ventricular Dysfunction after Pulmonary Artery Banding in Rats

(2011) Harm J. Bogaard et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Protective roles of SIRT1 in atherosclerosis

(2011) Sokrates Stein et al.   CELL CYCLE

Loss of Methyl-CpG–Binding Domain Protein 2 Enhances Endothelial Angiogenesis and Protects Mice Against Hind-Limb Ischemic Injury

(2011) Xiaoquan Rao et al.   CIRCULATION

Flow-Dependent Regulation of Krüppel-Like Factor 2 Is Mediated by MicroRNA-92a

(2011) Wei Wu et al.   CIRCULATION

Vascular Smooth Muscle Cell Proliferation Is Influenced by let-7d MicroRNA and Its Interaction With KRAS

(2011) Man-Li Yu et al.   CIRCULATION JOURNAL

Pervasive roles of microRNAs in cardiovascular biology

(2011) Eric M. Small et al.   NATURE

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

MicroRNA-21 targets peroxisome proliferators-activated receptor-  in an autoregulatory loop to modulate flow-induced endothelial inflammation

(2011) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normal Shear Stress and Vascular Smooth Muscle Cells Modulate Migration of Endothelial Cells Through Histone Deacetylase 6 Activation and Tubulin Acetylation

(2010) Yan-Hua Wang et al.   ANNALS OF BIOMEDICAL ENGINEERING

Endothelial Atheroprotective and Anti-inflammatory Mechanisms

(2010) BRADFORD C. BERK et al.   Annals of the New York Academy of Sciences

Exploring calmodulin-related proteins, which mediate development of hypertension, in vascular tissues of spontaneous hypertensive rats

(2010) Tatsuya Usui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNAs in Arterial Remodelling, Inflammation and Atherosclerosis

(2010) C. Weber et al.   CURRENT DRUG TARGETS

HDAC Inhibition Attenuates Inflammatory, Hypertrophic, and Hypertensive Responses in Spontaneously Hypertensive Rats

(2010) Jeffrey P. Cardinale et al.   HYPERTENSION

Mechanical Stretch Up-regulates MicroRNA-26a and Induces Human Airway Smooth Muscle Hypertrophy by Suppressing Glycogen Synthase Kinase-3β

(2010) Junaith S. Mohamed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis

(2010) Stefania Nicoli et al.   NATURE

Epigenetic modifications and human disease

(2010) Anna Portela et al.   NATURE BIOTECHNOLOGY

Chromatin Remodeling Pathways in Smooth Muscle Cell Differentiation, and Evidence for an Integral Role for p300

(2010) Joshua M. Spin et al.   PLoS One

Role of microRNA-23b in flow-regulation of Rb phosphorylation and endothelial cell growth

(2010) K.-C. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shear stress, SIRT1, and vascular homeostasis

(2010) Z. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-19a mediates the suppressive effect of laminar flow on cyclin D1 expression in human umbilical vein endothelial cells

(2010) X. Qin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro

(2010) Y. Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS

(2009) W. Wang et al.   BLOOD

Hematopoietic Stem Cell Development Is Dependent on Blood Flow

(2009) Trista E. North et al.   CELL

Histone Deacetylase 3 Is Critical in Endothelial Survival and Atherosclerosis Development in Response to Disturbed Flow

(2009) Anna Zampetaki et al.   CIRCULATION

Histone deacetylases modulate vascular smooth muscle cell migration induced by cyclic mechanical strain

(2009) Zhi-Qiang Yan et al.   JOURNAL OF BIOMECHANICS

Extracellular matrix alterations in hypertensive vascular remodeling

(2009) Catherine A. Lemarié et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Biomechanical forces promote embryonic haematopoiesis

(2009) Luigi Adamo et al.   NATURE

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

eNOS Activation by Physical Forces: From Short-Term Regulation of Contraction to Chronic Remodeling of Cardiovascular Tissues

(2009) J.-L. Balligand et al.   PHYSIOLOGICAL REVIEWS

The Genetic Signatures of Noncoding RNAs

(2009) John S. Mattick   PLoS Genetics

HDAC family: What are the cancer relevant targets?

(2008) Olaf Witt et al.   CANCER LETTERS

New twists in X-chromosome inactivation

(2008) Jennifer A Erwin et al.   CURRENT OPINION IN CELL BIOLOGY

miR-126 Regulates Angiogenic Signaling and Vascular Integrity

(2008) Jason E. Fish et al.   DEVELOPMENTAL CELL

Activation of p300 Histone Acetyltransferase Activity Is an Early Endothelial Response to Laminar Shear Stress and Is Essential for Stimulation of Endothelial Nitric-oxide Synthase mRNA Transcription

(2008) Wei Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetics in evolution and disease

(2008) Manel Esteller   LANCET

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS

Small non-coding RNAs in animal development

(2008) Giovanni Stefani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanotransduction gone awry

(2008) Diana E. Jaalouk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanotransduction in vascular physiology and atherogenesis

(2008) Cornelia Hahn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1

(2008) T. A. Harris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nitric Oxide Modulates Chromatin Folding in Human Endothelial Cells via Protein Phosphatase 2A Activation and Class II Histone Deacetylases Nuclear Shuttling

(2007) Barbara Illi et al.   CIRCULATION RESEARCH