A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase α

Chemical approaches to therapeutically target the metabolism and signaling of the endocannabinoid 2-AG and eicosanoids

(2014) Rebecca A. Kohnz et al.   CHEMICAL SOCIETY REVIEWS

Discovery of Glycine Sulfonamides as Dual Inhibitors of sn-1-Diacylglycerol Lipase α and α/β-Hydrolase Domain 6

(2014) Freek J. Janssen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-α in Brain

(2013) Marc P. Baggelaar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)

(2012) Dina Navia-Paldanius et al.   JOURNAL OF LIPID RESEARCH

DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses

(2012) Ku-Lung Hsu et al.   Nature Chemical Biology

The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling

(2012) M. Reisenberg et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Molecular characterization and identification of surrogate substrates for diacylglycerol lipase α

(2011) Donna L. Pedicord et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation

(2011) D. K. Nomura et al.   SCIENCE

Loss of Retrograde Endocannabinoid Signaling and Reduced Adult Neurogenesis in Diacylglycerol Lipase Knock-out Mice

(2010) Y. Gao et al.   JOURNAL OF NEUROSCIENCE

Continuous-Flow Enzyme Assay on a Microfluidic Chip for Monitoring Glycerol Secretion from Cultured Adipocytes

(2009) Anna M. Clark et al.   ANALYTICAL CHEMISTRY

Blockade of 2-Arachidonoylglycerol Hydrolysis by Selective Monoacylglycerol Lipase Inhibitor 4-Nitrophenyl 4-(Dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances Retrograde Endocannabinoid Signaling

(2009) B. Pan et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Targeting the endocannabinoid system: to enhance or reduce?

(2008) Vincenzo Di Marzo   NATURE REVIEWS DRUG DISCOVERY