A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable OGA Inhibitors
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable OGA Inhibitors
Authors
Keywords
-
Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 54, Issue 51, Pages 15429-15433
Publisher
Wiley
Online
2015-11-07
DOI
10.1002/anie.201507985
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Clinicopathologic and11C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer’s disease spectrum
- (2015) Melissa E. Murray et al. BRAIN
- Direct synthesis of imino-C-nucleoside analogues and other biologically active iminosugars
- (2015) Milan Bergeron-Brlek et al. Nature Communications
- O-GlcNAc and neurodegeneration: biochemical mechanisms and potential roles in Alzheimer's disease and beyond
- (2014) Scott A. Yuzwa et al. CHEMICAL SOCIETY REVIEWS
- Synthetic Strategies for the Synthesis and Transformation of Substituted Pyrrolinones as Advanced Intermediates for Rhazinilam Analogues
- (2014) Inga Kholod et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Nine of 16 Stereoisomeric Polyhydroxylated Proline Amides Are Potent β-N-Acetylhexosaminidase Inhibitors
- (2014) Benjamin J. Ayers et al. JOURNAL OF ORGANIC CHEMISTRY
- Increased O-GlcNAcylation reduces pathological tau without affecting its normal phosphorylation in a mouse model of tauopathy
- (2013) Danielle L. Graham et al. NEUROPHARMACOLOGY
- The carbohydrate-active enzymes database (CAZy) in 2013
- (2013) Vincent Lombard et al. NUCLEIC ACIDS RESEARCH
- A Tandem Organocatalytic α-Chlorination–Aldol Reaction That Proceeds with Dynamic Kinetic Resolution: A Powerful Tool for Carbohydrate Synthesis
- (2013) Milan Bergeron-Brlek et al. ORGANIC LETTERS
- Increasing Brain Protein O-GlcNAc-ylation Mitigates Breathing Defects and Mortality of Tau.P301L Mice
- (2013) Peter Borghgraef et al. PLoS One
- Elevation of cellular O-GlcNAcylation level by a potent and selective O-GlcNAcase inhibitor based on tetrahydroimidazopyridine scaffold
- (2012) Tiehai Li et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Scalable Syntheses of Both Enantiomers of DNJNAc and DGJNAc from Glucuronolactone: The Effect of N-Alkylation on Hexosaminidase Inhibition
- (2012) Andreas F. G. Glawar et al. CHEMISTRY-A EUROPEAN JOURNAL
- Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation
- (2012) Scott A Yuzwa et al. Nature Chemical Biology
- Iminosugar–ferrocene conjugates as potential anticancer agents
- (2012) Audrey Hottin et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease
- (2011) Gerald W. Hart et al. Annual Review of Biochemistry
- Taking Stock of Telomere Length at Telome Health
- (2011) Alice McCarthy CHEMISTRY & BIOLOGY
- Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation
- (2011) Caroline Smet-Nocca et al. Molecular BioSystems
- Cell-Penetrant, Nanomolar O-GlcNAcase Inhibitors Selective against Lysosomal Hexosaminidases
- (2010) Helge C. Dorfmueller et al. CHEMISTRY & BIOLOGY
- Recent Developments in the Synthesis of Pyrrolidine-Containing Iminosugars
- (2010) Bridget L. Stocker et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- GlcNAcstatins are nanomolar inhibitors of humanO-GlcNAcase inducing cellular hyper-O-GlcNAcylation
- (2009) Helge C. Dorfmueller et al. BIOCHEMICAL JOURNAL
- Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease
- (2009) F. Liu et al. BRAIN
- Design, Synthesis, and Biological Evaluation of Enantiomeric β-N-Acetylhexosaminidase Inhibitors LABNAc and DABNAc as Potential Agents against Tay-Sachs and Sandhoff Disease
- (2009) J. S. Shane Rountree et al. ChemMedChem
- Screening-based discovery of drug-likeO-GlcNAcase inhibitor scaffolds
- (2009) Helge C. Dorfmueller et al. FEBS LETTERS
- Tactics and strategies for the synthesis of iminosugar C-glycosides: a review
- (2009) Philippe Compain et al. TETRAHEDRON-ASYMMETRY
- A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo
- (2008) Scott A Yuzwa et al. Nature Chemical Biology
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started