Screening-based discovery of drug-likeO-GlcNAcase inhibitor scaffolds

GlcNAcstatins are nanomolar inhibitors of humanO-GlcNAcase inducing cellular hyper-O-GlcNAcylation

(2009) Helge C. Dorfmueller et al.   BIOCHEMICAL JOURNAL

Portrait of an Enzyme, a Complete Structural Analysis of a Multimodular β-N-Acetylglucosaminidase fromClostridium perfringens

(2009) Elizabeth Ficko-Blean et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemical Dissection of the Link between Streptozotocin, O-GlcNAc, and Pancreatic Cell Death

(2008) Shalini Pathak et al.   CHEMISTRY & BIOLOGY

Molecular characterization of nucleocytosolic O-GlcNAc transferases of Giardia lamblia and Cryptosporidium parvum

(2008) Sulagna Banerjee et al.   GLYCOBIOLOGY

Elevation of GlobalO-GlcNAc Levels in 3T3-L1 Adipocytes by Selective Inhibition ofO-GlcNAcase Does Not Induce Insulin Resistance

(2008) Matthew S. Macauley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo

(2008) Scott A Yuzwa et al.   Nature Chemical Biology

Structural and mechanistic insight into the basis of mucopolysaccharidosis IIIB

(2008) E. Ficko-Blean et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA