Association between discordant immunological response to highly active anti-retroviral therapy, regulatory T cell percentage, immune cell activation and very low-level viraemia in HIV-infected patients

Assessment of a novel flow cytometry technique of one-step intracellular staining: Example of FOXP3 in clinical samples

(2013) Julie Demaret et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Low-level viremia is associated with non-B subtypes in patients infected with HIV with virological success following HAART introduction

(2013) Julien Saison et al.   JOURNAL OF MEDICAL VIROLOGY

Enhanced CD4+ T-Cell Recovery with Earlier HIV-1 Antiretroviral Therapy

(2013) Tuan Le et al.   NEW ENGLAND JOURNAL OF MEDICINE

Poor Immune Reconstitution in HIV-Infected Patients Associates with High Percentage of Regulatory CD4+ T Cells

(2013) Ana Horta et al.   PLoS One

Mortality in well controlled HIV in the continuous antiretroviral therapy arms of the SMART and ESPRIT trials compared with the general population

(2012) Alison J. Rodger et al.   AIDS

Circulating interleukin-6 levels correlate with residual HIV viraemia and markers of immune dysfunction in treatment-controlled HIV-infected patients

(2012) Jean-Philippe Bastard et al.   ANTIVIRAL THERAPY

Incomplete Immune Recovery in HIV Infection: Mechanisms, Relevance for Clinical Care, and Possible Solutions

(2012) Julie C. Gaardbo et al.   Clinical & Developmental Immunology

Altered frequency and phenotype of CD4+ forkhead box protein 3+ T cells and its association with autoantibody production in human immunodeficiency virus-infected paediatric patients

(2012) R. J. Argüello et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

High IL-10 production by aged AIDS patients is related to high frequency of Tr-1 phenotype and low in vitro viral replication

(2012) Regis M. Andrade et al.   CLINICAL IMMUNOLOGY

Plasma HIV-1 RNA Detection Below 50 Copies/mL and Risk of Virologic Rebound in Patients Receiving Highly Active Antiretroviral Therapy

(2012) T. Doyle et al.   CLINICAL INFECTIOUS DISEASES

Ultrasensitive Assessment of Residual Low-Level HIV Viremia in HAART-Treated Patients and Risk of Virological Failure

(2012) Franco Maggiolo et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Differential alterations of the CD4 and CD8 T cell subsets in HIV-infected patients on highly active antiretroviral therapy with low CD4 T cell restoration

(2012) G. Mendez-Lagares et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Persistent low-level HIV-1 RNA between 20 and 50 copies/mL in antiretroviral-treated patients: associated factors and virological outcome

(2012) C. Charpentier et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Severe Immune Dysregulation Affects CD4+CD25hiFoxP3+ Regulatory T Cells in HIV-Infected Patients With Low-level CD4 T-Cell Repopulation Despite Suppressive Highly Active Antiretroviral Therapy

(2012) Gema Méndez-Lagares et al.   JOURNAL OF INFECTIOUS DISEASES

Early and Long-Lasting Alteration of Effector CD45RA−Foxp3high Regulatory T-Cell Homeostasis During HIV Infection

(2012) Federico Simonetta et al.   JOURNAL OF INFECTIOUS DISEASES

Homeostasis and Function of Regulatory T Cells in HIV/SIV Infection

(2012) M. E. Moreno-Fernandez et al.   JOURNAL OF VIROLOGY

HIV and Inflammation: Mechanisms and Consequences

(2012) Peter W. Hunt   Current HIV/AIDS Reports

Memory and naive-like regulatory CD4+ T cells expand during HIV-2 infection in direct association with CD4+ T-cell depletion irrespectively of viremia

(2011) Russell B. Foxall et al.   AIDS

Factors associated with paradoxical immune response to antiretroviral therapy in HIV infected patients: a case control study

(2011) Janaina AS Casotti et al.   BMC INFECTIOUS DISEASES

High T-cell immune activation and immune exhaustion among individuals with suboptimal CD4 recovery after 4 years of antiretroviral therapy in an African cohort

(2011) Damalie Nakanjako et al.   BMC INFECTIOUS DISEASES

Regulatory T cells and chronic immune activation in human immunodeficiency virus 1 (HIV-1)-infected children

(2011) R. Freguja et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Reduced Thymic Output Is a Major Mechanism of Immune Reconstitution Failure in HIV-Infected Patients After Long-term Antiretroviral Therapy

(2011) Taisheng Li et al.   CLINICAL INFECTIOUS DISEASES

Residual viraemia does not influence 1 year virological rebound in HIV-infected patients with HIV RNA persistently below 50 copies/mL

(2011) N. Gianotti et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Increased Frequency of Regulatory T Cells Accompanies Increased Immune Activation in Rectal Mucosae of HIV-Positive Noncontrollers

(2011) J. M. Shaw et al.   JOURNAL OF VIROLOGY

A Low T Regulatory Cell Response May Contribute to Both Viral Control and Generalized Immune Activation in HIV Controllers

(2011) Peter W. Hunt et al.   PLoS One

Immune activation, apoptosis, and Treg activity are associated with persistently reduced CD4+ T-cell counts during antiretroviral therapy

(2010) Stefania Piconi et al.   AIDS

The significance of activation markers on CD8 lymphocytes in human immunodeficiency syndrome: staging and prognostic value

(2010) M. LEVACHER et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Nadir CD4 T Cell Count as Predictor and High CD4 T Cell Intrinsic Apoptosis as Final Mechanism of Poor CD4 T Cell Recovery in Virologically Suppressed HIV‐Infected Patients: Clinical Implications

(2010) Eugènia Negredo et al.   CLINICAL INFECTIOUS DISEASES

Immune Exhaustion Occurs Concomitantly With Immune Activation and Decrease in Regulatory T Cells in Viremic Chronically HIV-1–Infected Patients

(2010) Meenakshi Sachdeva et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

T-Cell Dysfunction in HIV-1-Infected Patients With Impaired Recovery of CD4 Cells Despite Suppression of Viral Replication

(2010) Christian Erikstrup et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

The significance of very low-level viraemia detected by sensitive viral load assays in HIV infected patients on HAART

(2010) John Widdrington et al.   JOURNAL OF INFECTION

Regulatory T cells in HIV infection: pathogenic or protective participants in the immune response?

(2009) Barbara Fazekas de St Groth et al.   AIDS

Discordant responses on starting highly active antiretroviral therapy: suboptimal CD4 increases despite early viral suppression in the UK Collaborative HIV Cohort (UK CHIC) Study

(2009) R Gilson et al.   HIV MEDICINE

The Relationship of T-Regulatory Cell Subsets to Disease Stage, Immune Activation, and Pathogen-Specific Immunity in HIV Infection

(2009) Allan R Tenorio et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

CD4+CD25+/hiCD127loPhenotype Does Not Accurately Identify Regulatory T Cells in All Populations of HIV‐Infected Persons

(2009) Maria del Mar del Pozo‐Balado et al.   JOURNAL OF INFECTIOUS DISEASES

HIV-specific regulatory T cells are associated with higher CD4 cell counts in primary infection

(2008) Hassen Kared et al.   AIDS

Regulatory T cells in human immunodeficiency virus-infected patients are elevated and independent of immunological and virological status, as well as initiation of highly active anti-retroviral therapy

(2008) J. C. Gaardbo et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Level, phenotype and activation status of CD4+FoxP3+regulatory T cells in patients chronically infected with human immunodeficiency virus and/or hepatitis C virus

(2008) N. I. Rallón et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The decrease of regulatory T cells correlates with excessive activation and apoptosis of CD8+T cells in HIV-1-infected typical progressors, but not in long-term non-progressors

(2008) Yanmei Jiao et al.   IMMUNOLOGY

Preservation of FoxP3+ Regulatory T Cells in the Peripheral Blood of Human Immunodeficiency Virus Type 1-Infected Elite Suppressors Correlates with Low CD4+ T-Cell Activation

(2008) A. J. Chase et al.   JOURNAL OF VIROLOGY

Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients

(2008) F. S. Hodi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IMMUNOLOGY: Immunity Benefits from a Little Suppression

(2008) G. Kassiotis et al.   SCIENCE

Coordination of Early Protective Immunity to Viral Infection by Regulatory T Cells

(2008) J. M. Lund et al.   SCIENCE