High T-cell immune activation and immune exhaustion among individuals with suboptimal CD4 recovery after 4 years of antiretroviral therapy in an African cohort

Immune activation, apoptosis, and Treg activity are associated with persistently reduced CD4+ T-cell counts during antiretroviral therapy

(2010) Stefania Piconi et al.   AIDS

CD4 T-cell hyperactivation and susceptibility to cell death determine poor CD4 T-cell recovery during suppressive HAART

(2010) Marta Massanella et al.   AIDS

Nadir CD4 T Cell Count as Predictor and High CD4 T Cell Intrinsic Apoptosis as Final Mechanism of Poor CD4 T Cell Recovery in Virologically Suppressed HIV‐Infected Patients: Clinical Implications

(2010) Eugènia Negredo et al.   CLINICAL INFECTIOUS DISEASES

Persistent Microbial Translocation and Immune Activation in HIV‐1–Infected South Africans Receiving Combination Antiretroviral Therapy

(2010) Edana Cassol et al.   JOURNAL OF INFECTIOUS DISEASES

CD4+ T Cell Depletion, Immune Activation and Increased Production of Regulatory T Cells in the Thymus of HIV-Infected Individuals

(2010) Alessandra Bandera et al.   PLoS One

Mortality Reduction Associated with HIV/AIDS Care and Antiretroviral Treatment in Rural Malawi: Evidence from Registers, Coffin Sales and Funerals

(2010) Beatrice Mwagomba et al.   PLoS One

Changing mortality risk associated with CD4 cell response to antiretroviral therapy in South Africa

(2009) Stephen D Lawn et al.   AIDS

The Distribution and Immune Profile of T Cell Subsets in HIV-Infected Children from Uganda

(2009) Isaac Ssewanyana et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Programmed death (PD)-1 molecule and its ligand PD-L1 distribution among memory CD4 and CD8 T cell subsets in human immunodeficiency virus-1-infected individuals

(2009) G. Rosignoli et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Absence of CD4+T Cell Count Recovery Despite Receipt of Virologically Suppressive Highly Active Antiretroviral Therapy: Clinical Risk, Immunological Gaps, and Therapeutic Options

(2009) Lidia Gazzola et al.   CLINICAL INFECTIOUS DISEASES

Incomplete Peripheral CD4+Cell Count Restoration in HIV‐Infected Patients Receiving Long‐Term Antiretroviral Treatment

(2009) Colleen F. Kelley et al.   CLINICAL INFECTIOUS DISEASES

Scaling Up Antiretroviral Therapy in South Africa: The Impact of Speed on Survival

(2008) Rochelle P. Walensky et al.   JOURNAL OF INFECTIOUS DISEASES

Human immunodeficiency virus (HIV-1) infection selectively downregulates PD-1 expression in infected cells and protects the cells from early apoptosis in vitro and in vivo

(2008) Narasimhan J. Venkatachari et al.   VIROLOGY

Sub-optimal CD4 reconstitution despite viral suppression in an urban cohort on Antiretroviral Therapy (ART) in sub-Saharan Africa: Frequency and clinical significance

(2008) Damalie Nakanjako et al.   AIDS Research and Therapy

Relationship between T Cell Activation and CD4+T Cell Count in HIV‐Seropositive Individuals with Undetectable Plasma HIV RNA Levels in the Absence of Therapy

(2007) Peter W. Hunt et al.   JOURNAL OF INFECTIOUS DISEASES