The effects of diet-induced obesity on B cell function

Artery Tertiary Lymphoid Organs Contribute to Innate and Adaptive Immune Responses in Advanced Mouse Atherosclerosis

(2014) Sarajo Kumar Mohanta et al.   CIRCULATION RESEARCH

B Cells and Humoral Immunity in Atherosclerosis

(2014) Dimitrios Tsiantoulas et al.   CIRCULATION RESEARCH

B10 cell regulation of health and disease

(2014) Kathleen M. Candando et al.   IMMUNOLOGICAL REVIEWS

Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis

(2014) Georg F. Weber et al.   JOURNAL OF EXPERIMENTAL MEDICINE

B cells promote obesity-associated periodontitis and oral pathogen-associated inflammation

(2014) M. Zhu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Eicosapentaenoic and docosahexaenoic acid ethyl esters differentially enhance B-cell activity in murine obesity

(2014) Heather Teague et al.   JOURNAL OF LIPID RESEARCH

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

(2014) Ping Shen et al.   NATURE

CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype

(2014) Griselda V Zuccarino-Catania et al.   NATURE IMMUNOLOGY

Interleukin-35 induces regulatory B cells that suppress autoimmune disease

(2014) Ren-Xi Wang et al.   NATURE MEDICINE

Adipose Tissue Dendritic Cells Enhances Inflammation by Prompting the Generation of Th17 Cells

(2014) Yanhong Chen et al.   PLoS One

High Fat Diet Rapidly Suppresses B Lymphopoiesis by Disrupting the Supportive Capacity of the Bone Marrow Niche

(2014) Benjamin J. Adler et al.   PLoS One

The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza

(2013) Masayuki Morita et al.   CELL

Adipose Natural Regulatory B Cells Negatively Control Adipose Tissue Inflammation

(2013) Satoshi Nishimura et al.   Cell Metabolism

Class II Major Histocompatibility Complex Plays an Essential Role in Obesity-Induced Adipose Inflammation

(2013) Tuo Deng et al.   Cell Metabolism

Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases

(2013) Matthew Spite et al.   Cell Metabolism

Combined B- and T-cell deficiency does not protect against obesity-induced glucose intolerance and inflammation

(2013) Dov B. Ballak et al.   CYTOKINE

Impaired Local Production of Proresolving Lipid Mediators in Obesity and 17-HDHA as a Potential Treatment for Obesity-Associated Inflammation

(2013) A. Neuhofer et al.   DIABETES

T-Cell Costimulation Protects Obesity-Induced Adipose Inflammation and Insulin Resistance

(2013) J. Zhong et al.   DIABETES

Lipoxin A4modulates adaptive immunity by decreasing memory B-cell responses via an ALX/FPR2-dependent mechanism

(2013) Sesquile Ramon et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Diet-Induced Obese Mice Exhibit Altered Heterologous Immunity during a Secondary 2009 Pandemic H1N1 Infection

(2013) J. J. Milner et al.   JOURNAL OF IMMUNOLOGY

Microdomains in the membrane landscape shape antigen-presenting cell function

(2013) Malou Zuidscherwoude et al.   JOURNAL OF LEUKOCYTE BIOLOGY

n-3 PUFAs enhance the frequency of murine B-cell subsets and restore the impairment of antibody production to a T-independent antigen in obesity

(2013) Heather Teague et al.   JOURNAL OF LIPID RESEARCH

Dietary omega-3 fatty acids enhance the B1 but not the B2 cell immune response in mice with antigen-induced peritonitis

(2013) Valgerdur Tomasdottir et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

An Intrinsic Propensity of Murine Peritoneal B1b Cells to Switch to IgA in Presence of TGF-β and Retinoic Acid

(2013) Bishnudeo Roy et al.   PLoS One

B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile

(2013) J. DeFuria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fat to treat fat: Emerging relationship between dietary PUFA, endocannabinoids, and obesity

(2013) Jeffrey Kim et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

Identification of Adipose Tissue Dendritic Cells Correlated With Obesity-Associated Insulin-Resistance and Inducing Th17 Responses in Mice and Patients

(2012) A. Bertola et al.   DIABETES

Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production

(2012) Lydia Lynch et al.   IMMUNITY

Germinal center selection and the development of memory B and plasma cells

(2012) Mark J. Shlomchik et al.   IMMUNOLOGICAL REVIEWS

Natural killer T cells in adipose tissue prevent insulin resistance

(2012) Henk S. Schipper et al.   JOURNAL OF CLINICAL INVESTIGATION

TLR4 Activation Under Lipotoxic Conditions Leads to Synergistic Macrophage Cell Death through a TRIF-Dependent Pathway

(2012) J. D. Schilling et al.   JOURNAL OF IMMUNOLOGY

Resolvin D1 and Resolvin D2 Govern Local Inflammatory Tone in Obese Fat

(2012) J. Claria et al.   JOURNAL OF IMMUNOLOGY

Specialized Proresolving Mediators Enhance Human B Cell Differentiation to Antibody-Secreting Cells

(2012) S. Ramon et al.   JOURNAL OF IMMUNOLOGY

DHA-enriched fish oil targets B cell lipid microdomains and enhances ex vivo and in vivo B cell function

(2012) Eric A. Gurzell et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Fish oil increases raft size and membrane order of B cells accompanied by differential effects on function

(2012) Benjamin Drew Rockett et al.   JOURNAL OF LIPID RESEARCH

Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways

(2012) Shurong Huang et al.   JOURNAL OF LIPID RESEARCH

Global obesity: trends, risk factors and policy implications

(2012) Vasanti S. Malik et al.   Nature Reviews Endocrinology

Enhancement of hematopoiesis and lymphopoiesis in diet-induced obese mice

(2012) M. D. Trottier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Response Activator B Cells Protect Against Microbial Sepsis

(2012) P. J. Rauch et al.   SCIENCE

Protective Role of Natural IgM-Producing B1a Cells in Atherosclerosis

(2012) Tin Kyaw et al.   TRENDS IN CARDIOVASCULAR MEDICINE

(n-3) Fatty Acids Alleviate Adipose Tissue Inflammation and Insulin Resistance: Mechanistic Insights

(2012) Nishan S. Kalupahana et al.   Advances in Nutrition

The burden of obesity on infectious disease

(2011) Erik A Karlsson et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Obesity is associated with impaired immune response to influenza vaccination in humans

(2011) P A Sheridan et al.   INTERNATIONAL JOURNAL OF OBESITY

Mice Lacking Endogenous IL-10-Producing Regulatory B Cells Develop Exacerbated Disease and Present with an Increased Frequency of Th1/Th17 but a Decrease in Regulatory T Cells

(2011) N. A. Carter et al.   JOURNAL OF IMMUNOLOGY

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

(2011) Daniel A Winer et al.   NATURE MEDICINE

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Specialized pro-resolving lipid mediators in the inflammatory response: An update

(2010) Gerard Bannenberg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Toll-like receptors regulate B cell cytokine production in patients with diabetes

(2010) M. Jagannathan et al.   DIABETOLOGIA

B cell depletion reduces the development of atherosclerosis in mice

(2010) Hafid Ait-Oufella et al.   JOURNAL OF EXPERIMENTAL MEDICINE

n-3 PUFA improves fatty acid composition, prevents palmitate-induced apoptosis, and differentially modifies B cell cytokine secretion in vitro and ex vivo

(2010) Benjamin Drew Rockett et al.   JOURNAL OF LIPID RESEARCH

The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

(2010) Bing He et al.   NATURE IMMUNOLOGY

Lipid accumulation and dendritic cell dysfunction in cancer

(2010) Donna L Herber et al.   NATURE MEDICINE

Obesity predisposes to Th17 bias

(2009) Shawn Winer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Obesity-induced insulin resistance and hepatic steatosis are alleviated by ω-3 fatty acids: a role for resolvins and protectins

(2009) Ana González-Périz et al.   FASEB JOURNAL

Annual Medical Spending Attributable To Obesity: Payer-And Service-Specific Estimates

(2009) Eric A. Finkelstein et al.   HEALTH AFFAIRS

Fatty Acids Modulate Toll-like Receptor 4 Activation through Regulation of Receptor Dimerization and Recruitment into Lipid Rafts in a Reactive Oxygen Species-dependent Manner

(2009) Scott W. Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies

(2009) Prospective Studies Collaboration   LANCET

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

Normalization of obesity-associated insulin resistance through immunotherapy

(2009) Shawn Winer et al.   NATURE MEDICINE

A Regulatory B Cell Subset with a Unique CD1dhiCD5+ Phenotype Controls T Cell-Dependent Inflammatory Responses

(2008) Koichi Yanaba et al.   IMMUNITY