(n-3) Fatty Acids Alleviate Adipose Tissue Inflammation and Insulin Resistance: Mechanistic Insights

(n-3) Fatty Acids: Clinical Trials in People with Type 2 Diabetes

(2012) Suzanne Hendrich   Advances in Nutrition

Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century

(2011) Tanya L Blasbalg et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Differential Lipid Partitioning Between Adipocytes and Tissue Macrophages Modulates Macrophage Lipotoxicity and M2/M1 Polarization in Obese Mice

(2011) Xavier Prieur et al.   DIABETES

Selective Inactivation of c-Jun NH2-Terminal Kinase in Adipose Tissue Protects Against Diet-Induced Obesity and Improves Insulin Sensitivity in Both Liver and Skeletal Muscle in Mice

(2011) X. Zhang et al.   DIABETES

Stearidonic and Eicosapentaenoic Acids Inhibit Interleukin-6 Expression in ob/ob Mouse Adipose Stem Cells via Toll-Like Receptor-2–Mediated Pathways

(2011) Hui Wen Hsueh et al.   JOURNAL OF NUTRITION

Low Levels of the Omega-3 Index are Associated with Sudden Cardiac Arrest and Remain Stable in Survivors in the Subacute Phase

(2011) Hildegunn Aarsetoey et al.   LIPIDS

Evolutionary Aspects of Diet: The Omega-6/Omega-3 Ratio and the Brain

(2011) Artemis P. Simopoulos   MOLECULAR NEUROBIOLOGY

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

Relation of C-Reactive Protein to Abdominal Adiposity

(2010) Gabriel C. Brooks et al.   AMERICAN JOURNAL OF CARDIOLOGY

Absence of macrophage inflammatory protein-1α does not impact macrophage accumulation in adipose tissue of diet-induced obese mice

(2010) Bonnie K. Surmi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects

(2010) Da Young Oh et al.   CELL

Relationship between epicardial adipose tissue adipocyte size and MCP-1 expression

(2010) Sonia Eiras et al.   CYTOKINE

AMP-activated Protein Kinase  2 Subunit Is Required for the Preservation of Hepatic Insulin Sensitivity by n-3 Polyunsaturated Fatty Acids

(2010) T. Jelenik et al.   DIABETES

Targeting Ceramide Synthesis to Reverse Insulin Resistance

(2010) C. Schmitz-Peiffer   DIABETES

P-Selectin Glycoprotein Ligand-1 Deficiency Is Protective Against Obesity-Related Insulin Resistance

(2010) C. Sato et al.   DIABETES

Expression of Human Chemerin Induces Insulin Resistance in the Skeletal Muscle but Does Not Affect Weight, Lipid Levels, and Atherosclerosis in LDL Receptor Knockout Mice on High-Fat Diet

(2010) M. Becker et al.   DIABETES

Macrophage Adiponectin Expression Improves Insulin Sensitivity and Protects Against Inflammation and Atherosclerosis

(2010) N. Luo et al.   DIABETES

Transgenic Restoration of Long-Chain n-3 Fatty Acids in Insulin Target Tissues Improves Resolution Capacity and Alleviates Obesity-Linked Inflammation and Insulin Resistance in High-Fat-Fed Mice

(2010) P. J. White et al.   DIABETES

Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet

(2010) J. A. Ehses et al.   DIABETOLOGIA

Eicosapentaenoic Acid Prevents and Reverses Insulin Resistance in High-Fat Diet-Induced Obese Mice via Modulation of Adipose Tissue Inflammation

(2010) Nishan S. Kalupahana et al.   JOURNAL OF NUTRITION

The role of adipose tissue in mediating the beneficial effects of dietary fish oil

(2010) Michael J. Puglisi et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Role of adipose tissue renin–angiotensin system in metabolic and inflammatory diseases associated with obesity

(2010) Laurent Yvan-Charvet et al.   KIDNEY INTERNATIONAL

SPARC: a key player in the pathologies associated with obesity and diabetes

(2010) Katarina Kos et al.   Nature Reviews Endocrinology

Effects of Eicosapentaenoic Acid (EPA) Treatment on Insulin Sensitivity in an Animal Model of Diabetes: Improvement of the Inflammatory Status

(2010) Maite Figueras et al.   Obesity

Energy-Restricted High-Fat Diets Only Partially Improve Markers of Systemic and Adipose Tissue Inflammation

(2010) Nishan S. Kalupahana et al.   Obesity

Insulin signaling meets mitochondria in metabolism

(2010) Zhiyong Cheng et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Inflammation and impaired adipogenesis in hypertrophic obesity in man

(2009) Birgit Gustafson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Nuclear receptors and hepatic lipidogenic enzyme response to a dyslipidemic sucrose-rich diet and its reversal by fish oil n-3 polyunsaturated fatty acids

(2009) Gustavo J. Hein et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Enhancement in liver SREBP-1c/PPAR-α ratio and steatosis in obese patients: Correlations with insulin resistance and n-3 long-chain polyunsaturated fatty acid depletion

(2009) Paulina Pettinelli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Induction of lipid oxidation by polyunsaturated fatty acids of marine origin in small intestine of mice fed a high-fat diet

(2009) Evert M van Schothorst et al.   BMC GENOMICS

Harmonizing the Metabolic Syndrome

(2009) K.G.M.M. Alberti et al.   CIRCULATION

Eicosapentaenoic acid stimulates AMP-activated protein kinase and increases visfatin secretion in cultured murine adipocytes

(2009) Silvia Lorente-Cebrián et al.   CLINICAL SCIENCE

n-3 Fatty acids and rosiglitazone improve insulin sensitivity through additive stimulatory effects on muscle glycogen synthesis in mice fed a high-fat diet

(2009) O. Kuda et al.   DIABETOLOGIA

Obesity-induced insulin resistance and hepatic steatosis are alleviated by ω-3 fatty acids: a role for resolvins and protectins

(2009) Ana González-Périz et al.   FASEB JOURNAL

Uncoupling of Inflammation and Insulin Resistance by NF-κB in Transgenic Mice through Elevated Energy Expenditure

(2009) Tianyi Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipocytes as Immune Cells: Differential Expression of TWEAK, BAFF, and APRIL and Their Receptors (Fn14, BAFF-R, TACI, and BCMA) at Different Stages of Normal and Pathological Adipose Tissue Development

(2009) V.-I. Alexaki et al.   JOURNAL OF IMMUNOLOGY

Dietary Blueberry Attenuates Whole-Body Insulin Resistance in High Fat-Fed Mice by Reducing Adipocyte Death and Its Inflammatory Sequelae

(2009) Jason DeFuria et al.   JOURNAL OF NUTRITION

Early postprandial low-grade inflammation after high-fat meal in healthy rats: possible involvement of visceral adipose tissue

(2009) Joëlle Magné et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

Normalization of obesity-associated insulin resistance through immunotherapy

(2009) Shawn Winer et al.   NATURE MEDICINE

T-ing up inflammation in fat

(2009) Carey N. Lumeng et al.   NATURE MEDICINE

n3 and n6 polyunsaturated fatty acids differentially modulate prostaglandin E secretion but not markers of lipogenesis in adipocytes

(2009) Patrick Wortman et al.   Nutrition & Metabolism

Subcutaneous and visceral adipose tissue: structural and functional differences

(2009) M. Mohsen Ibrahim   Obesity Reviews

Dietary docosahexaenoic and eicosapentaenoic acid: Emerging mediators of inflammation

(2009) Robert S. Chapkin et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Enhanced angiogenesis in obesity and in response to PPARγ activators through adipocyte VEGF and ANGPTL4 production

(2008) Olga Gealekman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Identification and Characterization of Metabolically Benign Obesity in Humans

(2008) Norbert Stefan   ARCHIVES OF INTERNAL MEDICINE

Effects of Statins on Adipose Tissue Inflammation

(2008) Manabu Abe et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Effects of eicosapentaenoic acid ethyl ester on visfatin and apelin in lean and overweight (cafeteria diet-fed) rats

(2008) Nerea Pérez-Echarri et al.   BRITISH JOURNAL OF NUTRITION

Cellular and molecular effects ofn−3 polyunsaturated fatty acids on adipose tissue biology and metabolism

(2008) Pavel Flachs et al.   CLINICAL SCIENCE

Endurance training induces depot-specific changes in IL-10/TNF-α ratio in rat adipose tissue

(2008) F.S. Lira et al.   CYTOKINE

Fatty Acid Incubation of Myotubes From Humans With Type 2 Diabetes Leads to Enhanced Release of  -Oxidation Products Because of Impaired Fatty Acid Oxidation: Effects of Tetradecylthioacetic Acid and Eicosapentaenoic Acid

(2008) A. J. Wensaas et al.   DIABETES

Increase in Endoplasmic Reticulum Stress-Related Proteins and Genes in Adipose Tissue of Obese, Insulin-Resistant Individuals

(2008) G. Boden et al.   DIABETES

Reduced Adipose Tissue Oxygenation in Human Obesity: Evidence for Rarefaction, Macrophage Chemotaxis, and Inflammation Without an Angiogenic Response

(2008) M. Pasarica et al.   DIABETES

Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes

(2008) C. N. Lumeng et al.   DIABETES

Effect of hypocaloric diet-induced weight loss in obese women on plasma apelin and adipose tissue expression of apelin and APJ.

(2008) Isabelle Castan-Laurell et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Differential inflammatory status in rats susceptible or resistant to diet-induced obesity: effects of EPA ethyl ester treatment

(2008) Nerea Pérez-Echarri et al.   EUROPEAN JOURNAL OF NUTRITION

The Importance of the Omega-6/Omega-3 Fatty Acid Ratio in Cardiovascular Disease and Other Chronic Diseases

(2008) Artemis P. Simopoulos   EXPERIMENTAL BIOLOGY AND MEDICINE

The secretory function of adipocytes in the physiology of white adipose tissue

(2008) Ping Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Insulin sensitivity: modulation by nutrients and inflammation

(2008) Simon Schenk et al.   JOURNAL OF CLINICAL INVESTIGATION

Saturated Fatty Acid-Mediated Inflammation and Insulin Resistance in Adipose Tissue: Mechanisms of Action and Implications

(2008) Arion Kennedy et al.   JOURNAL OF NUTRITION