Immunological biomarkers: Catalysts for translational advances in autoimmune diabetes

CD8 T cell autoreactivity to preproinsulin epitopes with very low human leucocyte antigen class I binding affinity

(2012) J. R. F. Abreu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Innate and adaptive immune gene expression profiles as biomarkers in human type 1 diabetes

(2012) D. Han et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Network for Pancreatic Organ Donors with Diabetes (nPOD): developing a tissue biobank for type 1 diabetes

(2012) Martha Campbell-Thompson et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Transcriptional signatures as a disease-specific and predictive inflammatory biomarker for type 1 diabetes

(2012) H Levy et al.   GENES AND IMMUNITY

Cytometry by Time-of-Flight Shows Combinatorial Cytokine Expression and Virus-Specific Cell Niches within a Continuum of CD8+ T Cell Phenotypes

(2012) Evan W. Newell et al.   IMMUNITY

MHC Class II Tetramers

(2012) G. T. Nepom   JOURNAL OF IMMUNOLOGY

Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes

(2012) Anna M Bulek et al.   NATURE IMMUNOLOGY

The problems and promises of research into human immunology and autoimmune disease

(2012) Bart O Roep et al.   NATURE MEDICINE

Detection of four diabetes specific autoantibodies in a single radioimmunoassay: an innovative high-throughput approach for autoimmune diabetes screening

(2011) C. Tiberti et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Viruses and type 1 diabetes: ignorance acquires a better vocabulary

(2011) E. A. M. Gale   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Immunology in the clinic review series; focus on type 1 diabetes and viruses: the enterovirus link to type 1 diabetes: critical review of human studies

(2011) L. C. Stene et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Immunology in the clinic review series; focus on type 1 diabetes and viruses: how viral infections modulate beta cell function

(2011) F. A. Grieco et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Immunology in the clinic review series: focus on type 1 diabetes and viruses: the role of viruses in type 1 diabetes: a difficult dilemma

(2011) K. T. Coppieters et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Immunology in the clinic review series; focus on type 1 diabetes and viruses: role of antibodies enhancing the infection with Coxsackievirus-B in the pathogenesis of type 1 diabetes

(2011) D. Hober et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Immunology in the clinic review series; focus on type 1 diabetes and viruses: the innate immune response to enteroviruses and its possible role in regulating type 1 diabetes

(2011) K. Lind et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Immunology in the clinic review series; focus on type 1 diabetes and viruses: enterovirus, thymus and type 1 diabetes pathogenesis

(2011) H. Jaïdane et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Ultra-sensitive detection of rare T cell clones

(2011) Harlan Robins et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Discovery and Validation of Serum Protein Changes in Type 1 Diabetes Patients Using High Throughput Two Dimensional Liquid Chromatography-Mass Spectrometry and Immunoassays

(2011) Wenbo Zhi et al.   MOLECULAR & CELLULAR PROTEOMICS

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies

(2011) Tom L. Van Belle et al.   PHYSIOLOGICAL REVIEWS

Novel Automated Blood Separations Validate Whole Cell Biomarkers

(2011) Douglas E. Burger et al.   PLoS One

Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse

(2011) F. Crawford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of   cell death in diabetes using differentially methylated circulating DNA

(2011) E. M. Akirav et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Change you can B(cell)eive in: recent progress confirms a critical role for B cells in type 1 diabetes

(2011) Shannon K OʼNeill et al.   Current Opinion in Endocrinology Diabetes and Obesity

Isolation and preservation of peripheral blood mononuclear cells for analysis of islet antigen-reactive T cell responses: position statement of the T-Cell Workshop Committee of the Immunology of Diabetes Society

(2010) R. Mallone et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Simultaneous Detection of Circulating Autoreactive CD8+ T-Cells Specific for Different Islet Cell-Associated Epitopes Using Combinatorial MHC Multimers

(2010) J. H. Velthuis et al.   DIABETES

Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients

(2010) Jason L. Gaglia et al.   JOURNAL OF CLINICAL INVESTIGATION

Application of an End-to-End Biomarker Discovery Platform to Identify Target Engagement Markers in Cerebrospinal Fluid by High Resolution Differential Mass Spectrometry

(2010) Cloud P. Paweletz et al.   JOURNAL OF PROTEOME RESEARCH

A CD8+ T cell transcription signature predicts prognosis in autoimmune disease

(2010) Eoin F McKinney et al.   NATURE MEDICINE

The pancreas in human type 1 diabetes

(2010) Patrick A. Rowe et al.   Seminars in Immunopathology

Validity and Reproducibility of Measurement of Islet Autoreactivity by T-Cell Assays in Subjects With Early Type 1 Diabetes

(2009) K. C. Herold et al.   DIABETES

Defects in IL-2R Signaling Contribute to Diminished Maintenance of FOXP3 Expression in CD4+CD25+ Regulatory T-Cells of Type 1 Diabetic Subjects

(2009) S. A. Long et al.   DIABETES

Monocytes from Patients with Type 1 Diabetes Spontaneously Secrete Proinflammatory Cytokines Inducing Th17 Cells

(2009) E. M. Bradshaw et al.   JOURNAL OF IMMUNOLOGY

Concurrent detection of secreted products from human lymphocytes by microengraving: Cytokines and antigen-reactive antibodies

(2008) Elizabeth M. Bradshaw et al.   CLINICAL IMMUNOLOGY

Whole Genome Searching with Shotgun Proteomic Data: Applications for Genome Annotation

(2007) Joel R. Sevinsky et al.   JOURNAL OF PROTEOME RESEARCH