Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes

Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection

(2011) Yiyuan Yin et al.   EMBO JOURNAL

A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides

(2011) Linda Wooldridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC

(2011) Dhruv K. Sethi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics

(2011) O. Y. Borbulevych et al.   JOURNAL OF IMMUNOLOGY

T cell receptor recognition of self and foreign antigens in the induction of autoimmunity

(2011) Kai W. Wucherpfennig et al.   SEMINARS IN IMMUNOLOGY

Simultaneous Detection of Circulating Autoreactive CD8+ T-Cells Specific for Different Islet Cell-Associated Epitopes Using Combinatorial MHC Multimers

(2010) J. H. Velthuis et al.   DIABETES

Modification of MHC Anchor Residues Generates Heteroclitic Peptides That Alter TCR Binding and T Cell Recognition

(2010) D. K. Cole et al.   JOURNAL OF IMMUNOLOGY

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor

(2010) Siew Siew Pang et al.   NATURE

Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability

(2010) S. R. Burrows et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic and Structural Basis for Selection of a Ubiquitous T Cell Receptor Deployed in Epstein-Barr Virus Infection

(2010) John J. Miles et al.   PLoS Pathogens

T Cell Receptor Cross-reactivity Directed by Antigen-Dependent Tuning of Peptide-MHC Molecular Flexibility

(2009) Oleg Y. Borbulevych et al.   IMMUNITY

T Cell-Mediated Autoimmune Disease Due to Low-Affinity Crossreactivity to Common Microbial Peptides

(2009) Maria Harkiolaki et al.   IMMUNITY

xia2: an expert system for macromolecular crystallography data reduction

(2009) G. Winter   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor

(2009) David K. Cole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Bases for the Affinity-Driven Selection of a Public TCR against a Dominant Human Cytomegalovirus Epitope

(2009) S. Gras et al.   JOURNAL OF IMMUNOLOGY

Germline-encoded amino acids in the αβ T-cell receptor control thymic selection

(2009) James P. Scott-Browne et al.   NATURE

The molecular basis of TCR germline bias for MHC is surprisingly simple

(2009) K Christopher Garcia et al.   NATURE IMMUNOLOGY

Antigen recognition by CD1d-restricted NKT T cell receptors

(2009) Dale I. Godfrey et al.   SEMINARS IN IMMUNOLOGY

Conformational changes and flexibility in T-cell receptor recognition of peptide–MHC complexes

(2008) Kathryn M. Armstrong et al.   BIOCHEMICAL JOURNAL

Analysis of islet inflammation in human type 1 diabetes

(2008) A. Willcox et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Crossreactive T Cells Spotlight the Germline Rules for αβ T Cell-Receptor Interactions with MHC Molecules

(2008) Shaodong Dai et al.   IMMUNITY

The Fidelity, Occasional Promiscuity, and Versatility of T Cell Receptor Recognition

(2008) Dale I. Godfrey et al.   IMMUNITY

T cell receptor engagement of peptide-major histocompatibility complex class I does not modify CD8 binding

(2008) David K. Cole et al.   MOLECULAR IMMUNOLOGY