Synthesis and Anti-tumor Evaluation of Novel C-37 Modified Derivatives of Gambogic Acid

Gambogic acid inhibits tumor cell adhesion by suppressing integrin β1 and membrane lipid rafts-associated integrin signaling pathway

(2011) Chenglin Li et al.   BIOCHEMICAL PHARMACOLOGY

Studies on chemical modification and biology of a natural product, gambogic acid (III): Determination of the essential pharmacophore for biological activity

(2011) Xiaojian Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Gambogic acid inhibits Hsp90 and deregulates TNF-α/NF-κB in HeLa cells

(2010) Lianru Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Gambogenic Acid Inhibits Proliferation of A549 Cells through Apoptosis-Inducing and Cell Cycle Arresting

(2010) Qinglin Li et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Chemistry and Biology of the CagedGarciniaXanthones

(2010) Oraphin Chantarasriwong et al.   CHEMISTRY-A EUROPEAN JOURNAL

Studies on chemical modification and biology of a natural product, gambogic acid (II): Synthesis and bioevaluation of gambogellic acid and its derivatives from gambogic acid as antitumor agents

(2010) Jinxin Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Gambogic acid-induced degradation of mutant p53 is mediated by proteasome and related to CHIP

(2010) Jia Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Gambogic acid covalently modifies IκB kinase-β subunit to mediate suppression of lipopolysaccharide-induced activation of NF-κB in macrophages

(2009) Umamaheshwari D. Palempalli et al.   BIOCHEMICAL JOURNAL

General pharmacological properties, developmental toxicity, and analgesic activity of gambogic acid, a novel natural anticancer agent

(2009) Li Zhao et al.   DRUG AND CHEMICAL TOXICOLOGY

Posttranscriptional regulation of the telomerase hTERT by gambogic acid in human gastric carcinoma 823 cells

(2008) Qing Zhao et al.   CANCER LETTERS

Gambogic Acid Inhibits Angiogenesis and Prostate Tumor Growth by Suppressing Vascular Endothelial Growth Factor Receptor 2 Signaling

(2008) T. Yi et al.   CANCER RESEARCH

Studies on chemical structure modification and biology of a natural product, Gambogic acid (I): Synthesis and biological evaluation of oxidized analogues of gambogic acid

(2008) Jinxin Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Microtubule depolymerization and phosphorylation of c-Jun N-terminal kinase-1 and p38 were involved in gambogic acid induced cell cycle arrest and apoptosis in human breast carcinoma MCF-7 cells

(2008) Jing Chen et al.   LIFE SCIENCES