Gambogic acid-induced degradation of mutant p53 is mediated by proteasome and related to CHIP

Gambogic acid down-regulates MDM2 oncogene and induces p21Waf1/CIP1 expression independent of p53

(2009) Jing-Jing Rong et al.   CANCER LETTERS

Gambogic acid reduced bcl-2 expression via p53 in human breast MCF-7 cancer cells

(2009) Hongyan Gu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Posttranscriptional regulation of the telomerase hTERT by gambogic acid in human gastric carcinoma 823 cells

(2008) Qing Zhao et al.   CANCER LETTERS

Involvement of matrix metalloproteinase 2 and 9 in gambogic acid induced suppression of MDA-MB-435 human breast carcinoma cell lung metastasis

(2008) Qi Qi et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells

(2008) Hongyan Gu et al.   MOLECULAR CANCER THERAPEUTICS

Chaperone-dependent stabilization and degradation of p53 mutants

(2008) P Muller et al.   ONCOGENE