Synthesis, G-Quadruplex Stabilisation, Docking Studies, and Effect on Cancer Cells of Indolo[3,2-b]quinolines with One, Two, or Three Basic Side Chains
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Synthesis, G-Quadruplex Stabilisation, Docking Studies, and Effect on Cancer Cells of Indolo[3,2-b]quinolines with One, Two, or Three Basic Side Chains
Authors
Keywords
-
Journal
ChemMedChem
Volume -, Issue -, Pages n/a-n/a
Publisher
Wiley
Online
2013-08-19
DOI
10.1002/cmdc.201300288
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Efficient recovery of proteins from multiple source samples after trizol® or trizol®LS RNA extraction and long-term storage
- (2013) André ES Simões et al. BMC GENOMICS
- Conformational dynamics of the human propeller telomeric DNA quadruplex on a microsecond time scale
- (2013) Barira Islam et al. NUCLEIC ACIDS RESEARCH
- Sequences in the HSP90 promoter form G-quadruplex structures with selectivity for disubstituted phenyl bis-oxazole derivatives
- (2012) Stephan A. Ohnmacht et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?
- (2012) L. Neckers et al. CLINICAL CANCER RESEARCH
- Cobalt complexes bearing scorpionate ligands: synthesis, characterization, cytotoxicity and DNA cleavage
- (2012) Telma F. S. Silva et al. DALTON TRANSACTIONS
- Anticancer Activity and Cellular Repression of c-MYC by the G-Quadruplex-Stabilizing 11-Piperazinylquindoline Is Not Dependent on Direct Targeting of the G-Quadruplex in the c-MYC Promoter
- (2012) Peda V. L. Boddupally et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structural Basis for Telomeric G-Quadruplex Targeting by Naphthalene Diimide Ligands
- (2012) Gavin W. Collie et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- 1H NMR spectroscopic identification of protonable sites in cryptolepines with C-11 substituents containing two amino functionalities
- (2012) João Lavrado et al. MAGNETIC RESONANCE IN CHEMISTRY
- Targeting pancreatic cancer with a G-quadruplex ligand
- (2011) Mekala Gunaratnam et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Primer extension reactions as a tool to uncover folding motifs within complex G-rich sequences: analysis of the human KRAS NHE
- (2011) Manikandan Paramasivam et al. CHEMICAL COMMUNICATIONS
- Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA
- (2011) Yan Xu CHEMICAL SOCIETY REVIEWS
- Ethanesulfohydroxamic Acid Ester Prodrugs of Nonsteroidal Anti-inflammatory Drugs (NSAIDs): Synthesis, Nitric oxide and Nitroxyl Release, Cyclooxygenase Inhibition, Anti-inflammatory, and Ulcerogenicity Index Studies
- (2011) Zhangjian Huang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Incorporation of Basic Side Chains into Cryptolepine Scaffold: Structure−Antimalarial Activity Relationships and Mechanistic Studies
- (2011) João Lavrado et al. JOURNAL OF MEDICINAL CHEMISTRY
- G-Quadruplex-Binding Benzo[a]phenoxazines Down-Regulatec-KITExpression in Human Gastric Carcinoma Cells
- (2011) Keith I. E. McLuckie et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Solution Structure of a 2:1 Quindoline–c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design
- (2011) Jixun Dai et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structure of Human Telomeric DNA in Crowded Solution
- (2011) Brahim Heddi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
- (2011) Shankar Balasubramanian et al. NATURE REVIEWS DRUG DISCOVERY
- miR-143 Overexpression Impairs Growth of Human Colon Carcinoma Xenografts in Mice with Induction of Apoptosis and Inhibition of Proliferation
- (2011) Pedro M. Borralho et al. PLoS One
- Bis-alkylamine quindolone derivatives as new antimalarial leads
- (2010) João Lavrado et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- C-11 diamino cryptolepine derivatives NSC748392, NSC748393, and NSC748394: Anticancer profile and G-quadruplex stabilization
- (2010) João Lavrado et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Rational Design, Synthesis, Biophysical and Antiproliferative Evaluation of Fluorenone Derivatives with DNA G-Quadruplex Binding Properties
- (2010) Stefano Alcaro et al. ChemMedChem
- Indoloquinolines as Scaffolds for Drug Discovery
- (2010) J. Lavrado et al. CURRENT MEDICINAL CHEMISTRY
- Structural insights into G-quadruplexes: towards new anticancer drugs
- (2010) Danzhou Yang et al. Future Medicinal Chemistry
- Selectivity in Ligand Recognition of G-Quadruplex Loops†
- (2009) Nancy H. Campbell et al. BIOCHEMISTRY
- Design, synthesis and evaluation of 4,5-di-substituted acridone ligands with high G-quadruplex affinity and selectivity, together with low toxicity to normal cells
- (2009) Francisco Cuenca et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The structures of quadruplex nucleic acids and their drug complexes
- (2009) Stephen Neidle CURRENT OPINION IN STRUCTURAL BIOLOGY
- MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells
- (2009) Pedro M. Borralho et al. FEBS Journal
- Human telomeric G-quadruplex: The current status of telomeric G-quadruplexes as therapeutic targets in human cancer
- (2009) Stephen Neidle FEBS Journal
- Targeting Human Gastrointestinal Stromal Tumor Cells with a Quadruplex-Binding Small Molecule
- (2009) Mekala Gunaratnam et al. JOURNAL OF MEDICINAL CHEMISTRY
- Arrangements of human telomere DNA quadruplex in physiologically relevant K + solutions
- (2009) D. Renčiuk et al. NUCLEIC ACIDS RESEARCH
- 5-N-Methylated Quindoline Derivatives as Telomeric G-Quadruplex Stabilizing Ligands: Effects of 5-NPositive Charge on Quadruplex Binding Affinity and Cell Proliferation
- (2008) Yu-Jing Lu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structural Basis of DNA Quadruplex Recognition by an Acridine Drug
- (2008) Nancy H. Campbell et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Design of Selective G-quadruplex Ligands as Potential Anticancer Agents
- (2008) Jia-Heng Tan et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Stability and kinetics of G-quadruplex structures
- (2008) A. N. Lane et al. NUCLEIC ACIDS RESEARCH
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started