IlliciumSesquiterpenes: Divergent Synthetic Strategy and Neurotrophic Activity Studies

Total Synthesis of (−)-Jiadifenin

(2012) Yang Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Cyrneine A

(2012) Elangovan Elamparuthi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of (±)-Merrilactone A

(2012) Jianwei Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Neurotrophin Signaling via Long-Distance Axonal Transport

(2012) Praveen D. Chowdary et al.   Annual Review of Physical Chemistry

Nature-Inspired Total Synthesis of (−)-Fusarisetin A

(2012) Jing Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Formal Synthesis of Merrilactone A Using a Domino Cyanide 1,4-Addition–Aldol Cyclization

(2012) Naim Nazef et al.   ORGANIC LETTERS

Total Synthesis of (−)-Anisatin

(2012) Akihiro Ogura et al.   ORGANIC LETTERS

Model synthetic studies toward jiadifenin and majucin type seco-prezizaane natural products via a stereo- and enantioselective approach

(2012) Goverdhan Mehta et al.   TETRAHEDRON LETTERS

Permuting Diels–Alder and Robinson annulation stereopatterns

(2012) Feng Peng et al.   Chemical Science

Fusarisetin A: scalable total synthesis and related studies

(2012) Jing Xu et al.   Chemical Science

Synthesis of Withanolide A, Biological Evaluation of Its Neuritogenic Properties, and Studies on Secretase Inhibition

(2011) Chandan Kumar Jana et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Total Synthesis of (−)-Jiadifenolide

(2011) Jing Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Neuroprotection by Spice-Derived Nutraceuticals: You Are What You Eat!

(2011) Ramaswamy Kannappan et al.   MOLECULAR NEUROBIOLOGY

Potential therapeutic uses of BDNF in neurological and psychiatric disorders

(2011) Alan H. Nagahara et al.   NATURE REVIEWS DRUG DISCOVERY

Neuronal growth promoting sesquiterpene–neolignans; syntheses and biological studies

(2011) Xu Cheng et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Synthesis of (−)-Jiadifenin, a Potent Neurotrophic Modulator

(2011) Lynnie Trzoss et al.   ORGANIC LETTERS

Synthesis of the ABC Ring System of JiadifeninviaPd-Catalyzed Cyclizations

(2011) Kenichi Harada et al.   ORGANIC LETTERS

Enantioselective Synthesis of the ABC Ring Motif of Norzoanthamine Based on Asymmetric Robinson Annulation Reactions

(2011) Thong X. Nguyen et al.   ORGANIC LETTERS

Synthesis of (−)-callicarpenal, a potent arthropod repellent

(2011) Taotao Ling et al.   TETRAHEDRON

A robust and scalable synthesis of the potent neuroprotective agent (−)-huperzine A

(2011) Maung Kyaw Moe Tun et al.   Chemical Science

Synthesis of (±)-Merrilactone A and (±)-Anislactone A

(2010) Lei Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of (+)-Complanadine A, an Inducer of Neurotrophic Factor Excretion

(2010) Changxia Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of (+)-Complanadine A Using an Iridium-Catalyzed Pyridine C−H Functionalization

(2010) Daniel F. Fischer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Concise Total Synthesis of (+)-Lyconadin A

(2010) Takuya Nishimura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Neuroprotective Herbs and Foods from Different Traditional Medicines and Diets

(2010) Marcello Iriti et al.   MOLECULES

Bringing natural products into the fold – exploring the therapeutic lead potential of secondary metabolites for the treatment of protein-misfolding-related neurodegenerative diseases

(2010) P. Matthew Joyner et al.   NATURAL PRODUCT REPORTS

Natural products as a source of Alzheimer's drug leads

(2010) Philip Williams et al.   NATURAL PRODUCT REPORTS

Alzheimer's disease: strategies for disease modification

(2010) Martin Citron   NATURE REVIEWS DRUG DISCOVERY

An Unprecedented Method for the Generation oftert-Butylperoxy Radical Using DIB/TBHP Protocol: Solvent Effect and Application on Allylic Oxidation

(2010) Yi Zhao et al.   ORGANIC LETTERS

Deoxygedunin, a Natural Product with Potent Neurotrophic Activity in Mice

(2010) Sung-Wuk Jang et al.   PLoS One

Total synthesis of (±)-xanthocidin using FeCl3-mediated Nazarov reaction

(2010) Kentaro Yaji et al.   TETRAHEDRON

Highly selective formation of unsaturated esters or cascade reactions to α,ω-diesters by the methoxycarbonylation of alkynes catalysed by palladium complexes of 1,2-bis(ditertbutylphosphinomethyl)benzene

(2010) A. Alberto Núñez Magro et al.   Chemical Science

N-Aryl-substituted 3-(β-D-glucopyranosyloxy)-2-methyl-4(1H)-pyridinones as agents for Alzheimer's therapy

(2010) Lauren E. Scott et al.   Chemical Science

Total Synthesis and Structural Revision of (±)-Tricholomalides A and B

(2009) Zhang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total synthesis and study of 6-deoxyerythronolide B by late-stage C–H oxidation

(2009) Erik M. Stang et al.   Nature Chemistry

Total Synthesis of (±)-4,5-Bis-epi-Neovibsanin A and B: A Neurite Outgrowth Comparison Study

(2009) Annette P.-J. Chen et al.   ORGANIC LETTERS

Total Synthesis and Neuritotrophic Activity of Farinosone C and Derivatives

(2009) Henning J. Jessen et al.   ORGANIC LETTERS

A Hypervalent Iodine-Induced Double Annulation Enables a Concise Synthesis of the Pentacyclic Core Structure of the Cortistatins

(2009) Jessica L. Frie et al.   ORGANIC LETTERS

Novel Pentacyclicseco-Prezizaane-Type Sesquiterpenoids with Neurotrophic Properties fromIllicium jiadifengpi

(2009) Miwa Kubo et al.   ORGANIC LETTERS

Chemicals Possessing a Neurotrophin-Like Activity on Dopaminergic Neurons in Primary Culture

(2009) Fanny Schmidt et al.   PLoS One

Total syntheses of sesquiterpenes from Illicium species

(2009) Daisuke Urabe et al.   TETRAHEDRON

A Chiral Lewis Acid Strategy for Enantioselective Allylic CH Oxidation

(2008) Dustin J. Covell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Biology of Neurotrophins, Signalling Pathways, and Functional Peptide Mimetics of Neurotrophins and their Receptors

(2008) Stephen Skaper   CNS & Neurological Disorders-Drug Targets

Propargylic Oxidations Catalyzed by Dirhodium Caprolactamate in Water: Efficient Access to α,β-Acetylenic Ketones

(2008) Emily C. McLaughlin et al.   JOURNAL OF ORGANIC CHEMISTRY

Allylic Oxidations Catalyzed by Dirhodium Caprolactamate via Aqueoustert-Butyl Hydroperoxide: The Role of thetert-Butylperoxy Radical

(2008) Emily C. McLaughlin et al.   JOURNAL OF ORGANIC CHEMISTRY

Unified Strategy for the Synthesis of the “Miscellaneous”LycopodiumAlkaloids: Total Synthesis of (±)-Lyconadin A

(2008) Alakesh Bisai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Neuroactive Chondroitin Sulfate Glycomimetics

(2008) Manish Rawat et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of (+)-Cortistatin A, a Potent and Selective Inhibitor of Endothelial Cell Proliferation

(2008) Hong Myung Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of (±)-Merrilactone A

(2007) Wei He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY