Evaluation of targeting c-Src by the RGT-containing peptide as a novel antithrombotic strategy

Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network

(2013) T. J. Stalker et al.   BLOOD

A directional switch of integrin signalling and a new anti-thrombotic strategy

(2013) Bo Shen et al.   NATURE

Structural framework of c-Src activation by integrin  3

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Chronic estradiol treatment reduces platelet responses and protects mice from thromboembolism through the hematopoietic estrogen receptor  

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GDF-15 prevents platelet integrin activation and thrombus formation

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Collagen surfaces to measure thrombus formation under flow: possibilities for standardization

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The Interaction of Src Kinase with β3 Integrin Tails: A Potential Therapeutic Target in Thrombosis and Cancer

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The kinetics of  IIb 3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapy

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Wall shear over high degree stenoses pertinent to atherothrombosis

(2010) David L. Bark et al.   JOURNAL OF BIOMECHANICS

Lnk regulates integrin αIIbβ3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo

(2009) Hitoshi Takizawa et al.   JOURNAL OF CLINICAL INVESTIGATION

CIB1 deficiency results in impaired thrombosis: the potential role of CIB1 in outside-in signaling through integrin αIIbβ3

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An integrin αvβ3–c-Src oncogenic unit promotes anchorage-independence and tumor progression

(2009) Jay S Desgrosellier et al.   NATURE MEDICINE

A shear gradient–dependent platelet aggregation mechanism drives thrombus formation

(2009) Warwick S Nesbitt et al.   NATURE MEDICINE

The Tail of Integrins, Talin, and Kindlins

(2009) M. Moser et al.   SCIENCE

Outside-in: peptide versus integrin

(2008) J. S. Bennett   BLOOD

RGT, a synthetic peptide corresponding to the integrin  3 cytoplasmic C-terminal sequence, selectively inhibits outside-in signaling in human platelets by disrupting the interaction of integrin  IIb 3 with Src kinase

(2008) X. Su et al.   BLOOD