The kinetics of  IIb 3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapy

Antiplatelet therapies for the treatment of cardiovascular disease

(2010) Alan D. Michelson   NATURE REVIEWS DRUG DISCOVERY

Stabilizing Role of Platelet P2Y12 Receptors in Shear-Dependent Thrombus Formation on Ruptured Plaques

(2010) Reyhan Nergiz-Unal et al.   PLoS One

Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis

(2009) L. Lian et al.   BLOOD

CalDAG-GEFI is at the nexus of calcium-dependent platelet activation

(2009) L. Stefanini et al.   BLOOD

Pharmacokinetic, pharmacodynamic and clinical profile of novel antiplatelet drugs targeting vascular diseases

(2009) Jolanta M Siller-Matula et al.   BRITISH JOURNAL OF PHARMACOLOGY

The current state of antiplatelet therapy in acute coronary syndromes: The data and the real world

(2009) J. H. ALEXANDER   CLEVELAND CLINIC JOURNAL OF MEDICINE

Novel molecules in calcium signaling in platelets

(2009) W. BERGMEIER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Arterial thrombosis: relevance of a model with two levels of severity assessed by histologic, ultrastructural and functional characterization

(2009) B. HECHLER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Dysregulation of CalDAG-GEFI and CalDAG-GEFII predicts the severity of motor side-effects induced by anti-parkinsonian therapy

(2009) Jill R. Crittenden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of the spatial and temporal characteristics of platelet-delivered factor VIII-based clots

(2008) M. Neyman et al.   BLOOD

CalDAG-GEFI and protein kinase C represent alternative pathways leading to activation of integrin  IIb 3 in platelets

(2008) S. M. Cifuni et al.   BLOOD

The GPIIb/IIIa (integrin  IIb 3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend

(2008) B. S. Coller et al.   BLOOD

Microfluidic focal thrombosis model for measuring murine platelet deposition and stability: PAR4 signaling enhances shear-resistance of platelet aggregates

(2008) K. B. NEEVES et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Kindlin-3 is essential for integrin activation and platelet aggregation

(2008) Markus Moser et al.   NATURE MEDICINE