Structural framework of c-Src activation by integrin  3

The Interaction of Src Kinase with β3 Integrin Tails: A Potential Therapeutic Target in Thrombosis and Cancer

(2011) Stephan Huveneers et al.   TheScientificWorldJOURNAL

The final steps of integrin activation: the end game

(2010) Sanford J. Shattil et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

NMR analysis of the  IIb 3 cytoplasmic interaction suggests a mechanism for integrin regulation

(2010) D. G. Metcalf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An integrin αvβ3–c-Src oncogenic unit promotes anchorage-independence and tumor progression

(2009) Jay S Desgrosellier et al.   NATURE MEDICINE

Src kinases as therapeutic targets for cancer

(2009) Lori C. Kim et al.   Nature Reviews Clinical Oncology

Structure of an integrin  IIb 3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation

(2009) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antithrombotic effects of targeting  IIb 3 signaling in platelets

(2008) A. J. Ablooglu et al.   BLOOD

RGT, a synthetic peptide corresponding to the integrin  3 cytoplasmic C-terminal sequence, selectively inhibits outside-in signaling in human platelets by disrupting the interaction of integrin  IIb 3 with Src kinase

(2008) X. Su et al.   BLOOD

Src and focal adhesion kinase as therapeutic targets in cancer

(2008) Valerie G Brunton et al.   CURRENT OPINION IN PHARMACOLOGY

Potential Molecular Mechanism for c-Src Kinase-mediated Regulation of Intestinal Cell Migration

(2008) Sijo Mathew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY