Fluorinated amino acids: compatibility with native protein structures and effects on protein–protein interactions

Organic fluorine compounds: a great opportunity for enhanced materials properties

(2011) Ricarda Berger et al.   CHEMICAL SOCIETY REVIEWS

A Cation-  Interaction at a Phenylalanine Residue in the Glycine Receptor Binding Site Is Conserved for Different Agonists

(2011) S. A. Pless et al.   MOLECULAR PHARMACOLOGY

A Highly Active DNA Polymerase with a Fluorous Core

(2010) Bastian Holzberger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Specific Heterodimerization Mediated by Quadrupole Interactions

(2010) Hong Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Introducing Quadrupole Interactions into the Peptide Design Toolkit

(2010) Hana Robson Marsden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Binding of Fluorinated Phenylalanine α-Factor Analogues to Ste2p: Evidence for a Cation−π Binding Interaction between a Peptide Ligand and Its Cognate G Protein-Coupled Receptor

(2010) Subramanyam Tantry et al.   BIOCHEMISTRY

Evidence That Histidine Protonation of Receptor-Bound Anthrax Protective Antigen Is a Trigger for Pore Formation

(2010) D. Shyamali Wimalasena et al.   BIOCHEMISTRY

Site-Specific Incorporation of Fluorotyrosines into Proteins inEscherichia coliby Photochemical Disguise

(2010) Bryan J. Wilkins et al.   BIOCHEMISTRY

Thermodynamic Consequences of Incorporating 4-Substituted Proline Derivatives into a Small Helical Protein

(2010) Tong-Yuan Zheng et al.   BIOCHEMISTRY

Beyond the Canonical 20 Amino Acids: Expanding the Genetic Lexicon

(2010) Travis S. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Incorporation of Fluorinated Phenylalanine Generates Highly Specific Inhibitor of Proteasome’s Chymotrypsin-like Sites

(2010) Paul P. Geurink et al.   JOURNAL OF MEDICINAL CHEMISTRY

Replacing 32 Proline Residues by a Noncanonical Amino Acid Results in a Highly Active DNA Polymerase

(2010) Bastian Holzberger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Residue-specific global fluorination of Candida antarctica lipase B in Pichia pastoris

(2010) Nediljko Budisa et al.   Molecular BioSystems

Probing aromatic, hydrophobic, and steric effects on the self-assembly of an amyloid-β fragment peptide

(2010) F. Timur Senguen et al.   Molecular BioSystems

Crystal structure of the insect neuropeptide proctolin.

(2010) Judith A. K. Howard et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Collagen-Based Biomaterials for Tissue Engineering Applications

(2010) Rémi Parenteau-Bareil et al.   Materials

Collagen Structure and Stability

(2009) Matthew D. Shoulders et al.   Annual Review of Biochemistry

Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner

(2009) Kurt H. Piepenbrink et al.   BIOCHEMICAL JOURNAL

Engineering Protein Stability and Specificity Using Fluorous Amino Acids: The Importance of Packing Effects

(2009) Benjamin C. Buer et al.   BIOCHEMISTRY

Origin of the stability conferred upon collagen by fluorination

(2009) Matthew D. Shoulders et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Positional effects of monofluorinated phenylalanines on histone acetyltransferase stability and activity

(2009) Natalya Voloshchuk et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Incorporation of non-natural modules into proteins: structural features beyond the genetic code

(2009) Ulrich Arnold   BIOTECHNOLOGY LETTERS

Effects of Fluorination on the Folding Kinetics of a Heterodimeric Coiled Coil

(2009) Mario Salwiczek et al.   CHEMBIOCHEM

Position-Dependent Effects of Fluorinated Amino Acids on the Hydrophobic Core Formation of a Heterodimeric Coiled Coil

(2009) Mario Salwiczek et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rational Design of α-Conotoxin Analogues Targeting α7 Nicotinic Acetylcholine Receptors

(2009) Christopher Armishaw et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fluorine in Protein Environments: A QM and MD Study

(2009) Sergey A. Samsonov et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Probing the Coupling between Proton and Electron Transfer in Photosystem II Core Complexes Containing a 3-Fluorotyrosine

(2009) Fabrice Rappaport et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effect of Highly Fluorinated Amino Acids on Protein Stability at a Solvent-Exposed Position on an Internal Strand of Protein G B1 Domain

(2009) Hsien-Po Chiu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoelectronic effects on the transition barrier of polyproline conformational interconversion

(2009) Yi-Chun Chiang et al.   PROTEIN SCIENCE

Direct and continuous assay for prolyl 4-hydroxylase

(2008) Kelly L. Gorres et al.   ANALYTICAL BIOCHEMISTRY

Chemoselective Ligation and Modification Strategies for Peptides and Proteins

(2008) Christian P. R. Hackenberger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protein Design by Directed Evolution

(2008) Christian Jäckel et al.   Annual Review of Biophysics

Conformational Preferences of Substrates for Human Prolyl 4-Hydroxylase†

(2008) Kelly L. Gorres et al.   BIOCHEMISTRY

The Fluorous Effect in Proteins: Properties of α4F6, a 4-α-Helix Bundle Protein with a Fluorocarbon Core†

(2008) Lindsey M. Gottler et al.   BIOCHEMISTRY

Using Fluorous Amino Acids To Probe the Effects of Changing Hydrophobicity on the Physical and Biological Properties of the β-Hairpin Antimicrobial Peptide Protegrin-1†

(2008) Lindsey M. Gottler et al.   BIOCHEMISTRY

Photostability of green and yellow fluorescent proteins with fluorinated chromophores, investigated by fluorescence correlation spectroscopy

(2008) S. Veettil et al.   BIOPHYSICAL CHEMISTRY

Using Fluorous Amino Acids to Modulate the Biological Activity of an Antimicrobial Peptide

(2008) Lindsey M. Gottler et al.   CHEMBIOCHEM

Biosynthesis and Stability of Coiled-Coil Peptides Containing (2S,4R)-5,5,5-Trifluoroleucine and (2S,4S)-5,5,5-Trifluoroleucine

(2008) Jin Kim Montclare et al.   CHEMBIOCHEM

Synthetic strategies to α-trifluoromethyl and α-difluoromethyl substituted α-amino acids

(2008) René Smits et al.   CHEMICAL SOCIETY REVIEWS

Intracellular uptake and inhibitory activity of aromatic fluorinated amino acids in human breast cancer cells

(2008) Christoph Giese et al.   ChemMedChem

Incorporation of fluoroprolines to proctolin: Study on the effect of a fluorine atom toward peptidic conformation

(2008) Takamasa Kitamoto et al.   JOURNAL OF FLUORINE CHEMISTRY

19F NMR applications in chemical biology

(2008) Steven L. Cobb et al.   JOURNAL OF FLUORINE CHEMISTRY

Influence of Selective Fluorination on the Biological Activity and Proteolytic Stability of Glucagon-like Peptide-1

(2008) He Meng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Effects of tryptophan residue fluorination on streptavidin stability and biotin–streptavidin interactions via molecular dynamics simulations

(2008) Jarosław J. Panek et al.   JOURNAL OF MOLECULAR MODELING

A Cation-  Interaction in the Binding Site of the Glycine Receptor Is Mediated by a Phenylalanine Residue

(2008) S. A. Pless et al.   JOURNAL OF NEUROSCIENCE

Expanding the Fluorous Arsenal: Tetrafluorinated Phenylalanines for Protein Design

(2008) Hong Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Peptide-based biopolymers in biomedicine and biotechnology

(2008) Dominic Chow et al.   MATERIALS SCIENCE & ENGINEERING R-REPORTS

Synthesis of 3,5-Difluorotyrosine-Containing Peptides: Application in Substrate Profiling of Protein Tyrosine Phosphatases

(2008) Bhaskar Gopishetty et al.   ORGANIC LETTERS

Synthetic Biology of Proteins: Tuning GFPs Folding and Stability with Fluoroproline

(2008) Thomas Steiner et al.   PLoS One

Non-Natural and Photo-Reactive Amino Acids as Biochemical Probes of Immune Function

(2008) Marta Gómez-Nuñez et al.   PLoS One

Thrombogenic collagen-mimetic peptides: Self-assembly of triple helix-based fibrils driven by hydrophobic interactions

(2008) M. A. Cejas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Red fluorescent protein variants with incorporated non-natural amino acid analogues

(2008) A. Goulding et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Molecular dynamics guided study of salt bridge length dependence in both fluorinated and non-fluorinated parallel dimeric coiled-coils

(2008) Scott S. Pendley et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Singlet Oxygen Photosensitization by EGFP and its Chromophore HBDI

(2007) Ana Jiménez-Banzo et al.   BIOPHYSICAL JOURNAL

Understanding organofluorine chemistry. An introduction to the C–F bond

(2007) David O'Hagan   CHEMICAL SOCIETY REVIEWS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS

Preparation and conformational study of CF3-containing enkephalin-derived oligopeptide

(2007) Takamasa Kitamoto et al.   TETRAHEDRON