Beyond the Canonical 20 Amino Acids: Expanding the Genetic Lexicon

Efforts Toward the Direct Experimental Characterization of Enzyme Microenvironments: Tyrosine100 in Dihydrofolate Reductase

(2009) Dan Groff et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Evolution of Amber Suppressor tRNAs for Efficient Bacterial Production of Proteins Containing Nonnatural Amino Acids

(2009) Jiantao Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Facile System for Encoding Unnatural Amino Acids in Mammalian Cells

(2009) Peng R. Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Expanding the Genetic Repertoire of the Methylotrophic YeastPichia pastoris†

(2009) Travis S. Young et al.   BIOCHEMISTRY

Photocleavage of the Polypeptide Backbone by 2-Nitrophenylalanine

(2009) Francis B. Peters et al.   CHEMISTRY & BIOLOGY

An Enhanced System for Unnatural Amino Acid Mutagenesis in E. coli

(2009) Travis S. Young et al.   JOURNAL OF MOLECULAR BIOLOGY

Genetic Incorporation of a Metal-Ion Chelating Amino Acid into Proteins as a Biophysical Probe

(2009) Hyun Soo Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evolution of Proteins with Genetically Encoded “Chemical Warheads”

(2009) Chang C. Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genetic Incorporation of a Small, Environmentally Sensitive, Fluorescent Probe into Proteins inSaccharomyces cerevisiae

(2009) Hyun Soo Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FTIR analysis of GPCR activation using azido probes

(2009) Shixin Ye et al.   Nature Chemical Biology

Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids

(2009) J. Grunewald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Genetically Encoded Boronate-Containing Amino Acid

(2008) Eric Brustad et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Site-Specific Incorporation of Methyl- and Acetyl-Lysine Analogues into Recombinant Proteins

(2008) Jiantao Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Adding l-lysine derivatives to the genetic code of mammalian cells with engineered pyrrolysyl-tRNA synthetases

(2008) Takahito Mukai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Unnatural Amino Acid Replacement in a Yeast G Protein-Coupled Receptor in Its Native Environment†

(2008) Li-Yin Huang et al.   BIOCHEMISTRY

Biosynthesis of a Site-Specific DNA Cleaving Protein

(2008) Hyun Soo Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In vivoIncorporation of Unnatural Amino Acids to Probe Structure, Dynamics, and Ligand Binding in a Large Protein by Nuclear Magnetic Resonance Spectroscopy

(2008) Susan E. Cellitti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New Methods Enabling Efficient Incorporation of Unnatural Amino Acids in Yeast

(2008) Qian Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A General and Efficient Method for the Site-Specific Dual-Labeling of Proteins for Single Molecule Fluorescence Resonance Energy Transfer

(2008) Eric M. Brustad et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genetically encoding Nε-acetyllysine in recombinant proteins

(2008) Heinz Neumann et al.   Nature Chemical Biology

Protein evolution with an expanded genetic code

(2008) C. C. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Addition of an α-Hydroxy Acid to the Genetic Code of Bacteria

(2007) Jiantao Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION