Activation of C–F bonds α to C–C multiple bonds

A Copper(I)-Catalyzed Enantioselective γ-Boryl Substitution of Trifluoromethyl-Substituted Alkenes: Synthesis of Enantioenriched γ,γ-gem -Difluoroallylboronates

(2018) Ryoto Kojima et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Solvent-Dependent Asymmetric Synthesis of Alkynyl and Monofluoroalkenyl Isoindolinones by CpRhIII -Catalyzed C−H Activation

(2018) Teng Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereochemical outcomes of C–F activation reactions of benzyl fluoride

(2018) Neil S Keddie et al.   Beilstein Journal of Organic Chemistry

NHC-catalyzed [4+2] cycloaddition reactions for the synthesis of 3′-spirocyclic oxindoles via a C–F bond cleavage protocol

(2018) Jun Yan et al.   CHEMICAL COMMUNICATIONS

Efficient and Direct Synthesis of γ-Amino-α,β-Unsaturated Amides by Catalyzed Allylic Substitution of α-Fluoroenamides: Toward to Synthesis of Hybrid Peptides and Indolizidines

(2018) K. Harsha vardhan Reddy et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Oxidative Difluoromethylation of Tetrahydroisoquinolines Using TMSCF2SPh: Synthesis of Fluorinated Pyrrolo[2,1-a]isoquinolines and Benzo[a]quinolizidines

(2018) Teerachai Punirun et al.   JOURNAL OF ORGANIC CHEMISTRY

Ir(III)-Catalyzed Carbocarbation of Alkynes through Undirected Double C–H Bond Activation of Anisoles

(2018) Fedor Romanov-Michailidis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Copper-Catalyzed Reductive Defluorination of β-Trifluoromethylated Enones via Oxidative Homocoupling of Grignard Reagents

(2018) Xiaoting Wu et al.   ORGANIC LETTERS

Synthesis of 4-Difluoromethylquinolines by NHC-Catalyzed Umpolung of Imines

(2018) Atanu Patra et al.   ORGANIC LETTERS

Selective Late-Stage Hydrodefluorination of Trifluoromethylarenes: A Facile Access to Difluoromethylarenes

(2017) Socrates B. Munoz et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Unusual reactivity of trifluoromethyl groups in meso -tetrakis(trifluoromethyl)porphyrin

(2017) Anikó Nemes et al.   JOURNAL OF FLUORINE CHEMISTRY

Unusual reactivity of fluoro-enolates with dialkyl azodicarboxylates: Synthesis of isatin-hydrazones

(2017) Yi Zhu et al.   JOURNAL OF FLUORINE CHEMISTRY

Cooperative Al–H Bond Activation in DIBAL-H: Catalytic Generation of an Alumenium-Ion-Like Lewis Acid for Hydrodefluorinative Friedel–Crafts Alkylation

(2017) Francis Forster et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Defluoroalkylation of Trifluoromethylaromatics with Unactivated Alkenes

(2017) Hengbin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective Single C(sp3)–F Bond Cleavage in Trifluoromethylarenes: Merging Visible-Light Catalysis with Lewis Acid Activation

(2017) Kang Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C–F Bond Cleavage Enabled Redox-Neutral [4+1] Annulation via C–H Bond Activation

(2017) Cheng-Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-catalyzed synthesis of monofluoroalkenes from 3,3-difluoropropenes using dimethylmalonate and derivatives as nucleophiles

(2017) Myriam Drouin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Divergent synthesis from reactions of 2-trifluoromethyl-1,3-conjugated enynes with N-acetylated 2-aminomalonates

(2017) Jieru Yang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Niobium(v)-catalyzed defluorinative triallylation of α,α,α-trifluorotoluene derivatives by triple C–F bond activation

(2017) Kodai Saito et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Domino C–F Bond Activation of the CF3 Group: Synthesis of Fluorinated Dibenzo[a,c][7]annulenes from 2-(Trifluoromethyl)-1-alkenes and 2,2′-Diceriobiaryls

(2017) Takeshi Fujita et al.   ORGANIC LETTERS

Me3SiCF2Br-Self-Assisted Domino Reaction: Catalytic Synthesis of α,α-Difluorocyclopentanones from Methylvinylketones

(2017) Jian Chang et al.   ORGANIC LETTERS

Aluminum-Catalyzed Cross-Coupling of Silylalkynes with Aliphatic C–F Bonds

(2017) Amit K. Jaiswal et al.   ORGANIC LETTERS

Synthesis of gem-Difluoroallylboronates via FeCl2-Catalyzed Boration/β-Fluorine Elimination of Trifluoromethyl Alkenes

(2017) Yang Liu et al.   ORGANIC LETTERS

The stability and reactivity of tri-, di-, and monofluoromethyl/methoxy/methylthio groups on arenes under acidic and basic conditions

(2017) Lingfei Wang et al.   Organic Chemistry Frontiers

Synthesis of Gly-ψ[(Z)CF═CH]-Phe, a Fluoroalkene Dipeptide Isostere, and Its Incorporation into a Leu-enkephalin Peptidomimetic

(2016) Jean-François Nadon et al.   ACS Chemical Neuroscience

C−C Coupling of Benzyl Fluorides Catalyzed by an Electrophilic Phosphonium Cation

(2016) Jiangtao Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Single C−F Bond Cleavage of Trifluoromethylarenes with an ortho -Silyl Group

(2016) Suguru Yoshida et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Enantioselective Nucleophilic Alkynylation of Allyl Fluorides Affording Chiral Skipped Ene-ynes

(2016) Satoshi Okusu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of 2-fluoro-2-pyrrolines via tandem reaction of α-trifluoromethyl-α,β-unsaturated carbonyl compounds with N-tosylated 2-aminomalonates

(2016) Jieru Yang et al.   CHEMICAL COMMUNICATIONS

Aluminum oxide mediated C–F bond activation in trifluoromethylated arenes

(2016) O. Papaianina et al.   CHEMICAL COMMUNICATIONS

C–F→Ln/An interactions in synthetic f-element chemistry

(2016) Haolin Yin et al.   DALTON TRANSACTIONS

Competing reaction pathways of 3,3,3-trifluoropropene at rhodium hydrido, silyl and germyl complexes: C–F bond activation versus hydrogermylation

(2016) Theresia Ahrens et al.   DALTON TRANSACTIONS

Discovery of 6-(difluoro(6-(4-fluorophenyl)-[1,2,4]triazolo[4,3- b ][1,2,4]triazin-3-yl)methyl)quinoline as a highly potent and selective c-Met inhibitor

(2016) Zhengsheng Zhan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Faster initiation in the Friedel-Crafts reaction of benzyl fluorides using trifluoroacetic acid as activator

(2016) Rémy Hemelaere et al.   JOURNAL OF FLUORINE CHEMISTRY

Iodine(III)-Mediated Selective Intermolecular C–H Amination for the Chemical Diversification of Tryptamines

(2016) Alexandra E. Bosnidou et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Functionalized gem-Difluoroalkenes via a Photocatalytic Decarboxylative/Defluorinative Reaction

(2016) Tiebo Xiao et al.   JOURNAL OF ORGANIC CHEMISTRY

Rhodium-Catalyzed Asymmetric Arylation/Defluorination of 1-(Trifluoromethyl)alkenes Forming Enantioenriched 1,1-Difluoroalkenes

(2016) Yinhua Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Platform for Ring-Fluorinated Benzoheterole Derivatives: Palladium-Catalyzed Regioselective 1,1-Difluoroallylation and Heck Cyclization

(2016) Takeshi Fujita et al.   ORGANIC LETTERS

Catalytic activation of a single C–F bond in trifluoromethyl arenes

(2016) Hester Dang et al.   Chemical Science

Enantioselective fluorination of α-branched aldehydes and subsequent conversion to α-hydroxyacetals via stereospecific C–F bond cleavage

(2016) Kazutaka Shibatomi et al.   Chemical Science

Catalytic halodefluorination of aliphatic carbon–fluorine bonds

(2016) Kelvin K. K. Goh et al.   RSC Advances

Transformation of Trifluorotoluenes Triggered by Titanium(IV) Chloride-Catalyzed Hydrodefluorination using Hydrosilanes

(2015) Takayuki Yamada et al.   ADVANCED SYNTHESIS & CATALYSIS

Use of Trifluoromethyl Groups for Catalytic Benzylation and Alkylation with Subsequent Hydrodefluorination

(2015) Jiangtao Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Trichloromethylation of MBH-Fluorides with Chloroform Based on Silicon-assisted C−F Activation and Carbanion Exchange Induced by a Ruppert-Prakash Reagent

(2015) Takayuki Nishimine et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Elusive Silane-Alane Complex [SiH⋅⋅⋅Al]: Isolation, Characterization, and Multifaceted Frustrated Lewis Pair Type Catalysis

(2015) Jiawei Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A simple base-mediated synthesis of diverse functionalized ring-fluorinated 4H-pyrans via double direct C–F substitutions

(2015) Jieru Yang et al.   CHEMICAL COMMUNICATIONS

Monofluorination of Organic Compounds: 10 Years of Innovation

(2015) Pier Alexandre Champagne et al.   CHEMICAL REVIEWS

Catalytic defluorinative [3 + 2] cycloaddition of trifluoromethylalkenes with alkynes via reduction of nickel(ii) fluoride species

(2015) Takeshi Fujita et al.   DALTON TRANSACTIONS

Synthesis of 3-Fluoro-2-hetarylindoles and 3,3-Difluoro-2-hetarylindolines through Lewis Acid-Catalyzed Formation of 3,3-Difluoroindolium Ions

(2015) Jacqueline Zi Mei Fong et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Fluorine-Containing Exoalkylidene β-Lactams

(2015) Assaad Nasr El Dine et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of monofluoroalkenes using a Pt-catalyzed amination reaction of cyclic 3,3-difluoropropenes with secondary aliphatic amines

(2015) Jean-Denys Hamel et al.   JOURNAL OF FLUORINE CHEMISTRY

Review of recent advances in CF bond activation of aliphatic fluorides

(2015) Qian Shen et al.   JOURNAL OF FLUORINE CHEMISTRY

Mechanistic study on a unique S N 2′-type reaction of allylic alcohols with organolithium reagent accelerated by a proximal trifluoromethyl group

(2015) Hiromichi Egami et al.   JOURNAL OF FLUORINE CHEMISTRY

Revised mechanistic explanation for the alcohol-promoted amination of benzylic fluorides under highly concentrated conditions: Computational and experimental evidence on a model substrate

(2015) Pier Alexandre Champagne et al.   JOURNAL OF FLUORINE CHEMISTRY

Catalytic C–F activation via cationic group IV metallocenes

(2015) Dominik Lanzinger et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Synthesis of (Z)-fluoroallyl azides through aluminium-mediated defluorinative functionalization reactions

(2015) Azusa Sato et al.   TETRAHEDRON LETTERS

Electrochemical hydrodefluorination of fluoroaromatic compounds

(2015) Wen-Bin Wu et al.   TETRAHEDRON LETTERS

Carbon–fluorine bond activation for the synthesis of functionalized molecules

(2015) Teresa A. Unzner et al.   TETRAHEDRON LETTERS

Nickel-Catalyzed Allylic C(sp3)–F Bond Activation of Trifluoromethyl Groups via β-Fluorine Elimination: Synthesis of Difluoro-1,4-dienes

(2015) Tomohiro Ichitsuka et al.   ACS Catalysis

Friedel-Crafts Reaction of Benzyl Fluorides: Selective Activation of CF Bonds as Enabled by Hydrogen Bonding

(2014) Pier Alexandre Champagne et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Double CF Bond Activation through β-Fluorine Elimination: Nickel-Mediated [3+2] Cycloaddition of 2-Trifluoromethyl-1-alkenes with Alkynes

(2014) Tomohiro Ichitsuka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modern Carbon–Fluorine Bond Forming Reactions for Aryl Fluoride Synthesis

(2014) Michael G. Campbell et al.   CHEMICAL REVIEWS

Advances in Catalytic Enantioselective Fluorination, Mono-, Di-, and Trifluoromethylation, and Trifluoromethylthiolation Reactions

(2014) Xiaoyu Yang et al.   CHEMICAL REVIEWS

Functionalization of Fluorinated Molecules by Transition-Metal-Mediated C–F Bond Activation To Access Fluorinated Building Blocks

(2014) Theresia Ahrens et al.   CHEMICAL REVIEWS

A Transition-Metal-Free Synthesis of Fluorinated Naphthols

(2014) Jeffrey M. Hammann et al.   CHEMISTRY-A EUROPEAN JOURNAL

[Sb(C6F5)4][B(C6F5)4]: An Air Stable, Lewis Acidic Stibonium Salt That Activates Strong Element-Fluorine Bonds

(2014) Baofei Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Hydrodefluorination of Fluoromethanes at Room Temperature by Silylium-ion-like Surface Species

(2013) Mike Ahrens et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kinetic Resolution of Allyl Fluorides by Enantioselective Allylic Trifluoromethylation Based on Silicon-Assisted CF Bond Cleavage

(2013) Takayuki Nishimine et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Fluorinated Building Blocks by Transition-Metal-Mediated Hydrodefluorination Reactions

(2013) Moritz F. Kuehnel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Triol-promoted activation of C–F bonds: Amination of benzylic fluorides under highly concentrated conditions mediated by 1,1,1-tris(hydroxymethyl)propane

(2013) Pier Alexandre Champagne et al.   Beilstein Journal of Organic Chemistry

Solvent dependent reductive defluorination of aliphatic C–F bonds employing Sm(HMDS)2

(2013) Mario Janjetovic et al.   CHEMICAL COMMUNICATIONS

Mild allylic defluorination of 3,3-difluorobut-1-ene derivative activated by a phenylsulfonyl group

(2013) Youn Young Hong et al.   JOURNAL OF FLUORINE CHEMISTRY

Hydrodefluorinations of trifluorotoluenes by LiAlH4 and TiCl4

(2013) Takahiko Akiyama et al.   JOURNAL OF FLUORINE CHEMISTRY

C(sp3)–F Bond Activation of CF3-Substituted Anilines with Catalytically Generated Silicon Cations: Spectroscopic Evidence for a Hydride-Bridged Ru–S Dimer in the Catalytic Cycle

(2013) Timo Stahl et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh-catalyzed allylic C–F bond activation: the stereoselective synthesis of trisubstituted monofluoroalkenes and a mechanism study

(2013) He Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of 2-Aryl-3-fluoro-5-silylthiophenes via a Cascade Reactive Sequence

(2013) Kensuke Hirotaki et al.   ORGANIC LETTERS

Enabling Nucleophilic Substitution Reactions of Activated Alkyl Fluorides through Hydrogen Bonding

(2013) Pier Alexandre Champagne et al.   ORGANIC LETTERS

Lewis Acidity of Organofluorophosphonium Salts: Hydrodefluorination by a Saturated Acceptor

(2013) C. B. Caputo et al.   SCIENCE

Gold(I)-Catalyzed Diketonization of Alkynes and Its Application for the One-Pot Synthesis of Quinoxaline Derivatives

(2013) Yunkui Liu et al.   SYNLETT

Hydrodefluorination of carbon–fluorine bonds by the synergistic action of a ruthenium–palladium catalyst

(2013) Sara Sabater et al.   Nature Communications

Main-Group Lewis Acids for C–F Bond Activation

(2013) Timo Stahl et al.   ACS Catalysis

Highly Efficient Nickel(II) Chloride/Bis(tricyclohexylphosphine)nickel(II) Chloride-Cocatalyzed Hydrodefluorination of Fluoroarenes and Trifluorotoluenes with Superhydride

(2012) Wenwen Zhao et al.   ADVANCED SYNTHESIS & CATALYSIS

Substitution of Two Fluorine Atoms in a Trifluoromethyl Group: Regioselective Synthesis of 3-Fluoropyrazoles

(2012) Kohei Fuchibe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NiCl2(PCy3)2-catalyzed hydrodefluorination of fluoroarenes with LiAl(O-t-Bu)3H

(2012) Juan Xiao et al.   JOURNAL OF FLUORINE CHEMISTRY

Regio- and Diastereoselective Nickel-Catalyzed Allylation of Aromatic Aldehydes with α-Halo-β,β-difluoropropene Derivatives

(2012) Xiaowei Lin et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Substitution and Cross-Coupling of Benzylic Fluorides

(2012) George Blessley et al.   ORGANIC LETTERS

SN2′ Reaction of Allylic Difluorides with Lithium Amides and Thiolates

(2012) Maxime Bergeron et al.   ORGANIC LETTERS

Platinum-Catalyzed Substitution of Allylic Fluorides

(2012) Elena Benedetto et al.   ORGANOMETALLICS

Unexpected reactivity of trifluoromethylated olefins with indole: a mechanistic investigation

(2012) Mónica S. Estevão et al.   TETRAHEDRON LETTERS

Hydrogen bonds with fluorine. Studies in solution, in gas phase and by computations, conflicting conclusions from crystallographic analyses

(2012) Hans-Jörg Schneider   Chemical Science

The Use of Fluoride as a Leaving Group: SN2′ Displacement of a CF Bond on 3,3-Difluoropropenes with Organolithium Reagents To Give Direct Access to Monofluoroalkenes

(2011) Maxime Bergeron et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NHC-Cu-Catalyzed Enantioselective Hydroboration of Acyclic and Exocyclic 1,1-Disubstituted Aryl Alkenes

(2011) Rosa Corberán et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Hydrodefluorination of Fluoroarenes and Trifluorotoluenes with Superhydride (Lithium Triethylborohydride)

(2011) Jingjing Wu et al.   ChemCatChem

Exhaustive Chlorination of [B12H12]2−without Chlorine Gas and the Use of [B12Cl12]2−as a Supporting Anion in Catalytic Hydrodefluorination of Aliphatic C−F Bonds

(2011) Weixing Gu et al.   INORGANIC CHEMISTRY

Copper mediated defluorinative allylic alkylation of difluorohomoallyl alcohol derivatives directed to an efficient synthetic method for (Z)-fluoroalkene dipeptide isosteres

(2011) Daisuke Watanabe et al.   JOURNAL OF FLUORINE CHEMISTRY

Catalysis for fluorination and trifluoromethylation

(2011) Takeru Furuya et al.   NATURE

Protolytic defluorination of trifluoromethyl-substituted arenes

(2011) Anila Kethe et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Transformation of Anionically Activated Trifluoromethyl Groups to Heterocycles under Mild Aqueous Conditions

(2011) Jennifer X. Qiao et al.   ORGANIC LETTERS

Breaking C–F Bonds via Nucleophilic Attack of Coordinated Ligands: Transformations from C–F to C–X Bonds (X= H, N, O, S)

(2011) Ainara Nova et al.   ORGANOMETALLICS

Cu-deposits on Mg metal surfaces promote electron transfer reactions

(2011) Shinya Utsumi et al.   TETRAHEDRON

Copper-free defluorinative alkylation of allylic difluorides through Lewis acid-mediated C–F bond activation

(2011) Hikaru Yanai et al.   TETRAHEDRON LETTERS

Niobium-catalyzed Activation of CF3Group on Alkene: Synthesis of Substituted Indenes

(2010) Kohei Fuchibe et al.   CHEMISTRY LETTERS

AlCl3-mediated Defluorinative Diarylhydroxylation Transformation of CF3: Chemoselective Arylation of CF3and Chlorocarbonyl Groups Attached to Aromatic Rings

(2010) Akiko Okamoto et al.   CHEMISTRY LETTERS

Hydrodefluorination and Other Hydrodehalogenation of Aliphatic Carbon−Halogen Bonds Using Silylium Catalysis

(2010) Christos Douvris et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Tertiary Amides from Anionically Activated Aromatic Trifluoromethyl Groups

(2010) Gavin O’Mahony et al.   ORGANIC LETTERS

Electrosynthesis of fluorinated indole derivatives

(2010) Bin Yin et al.   TETRAHEDRON

Non-catalytic conversion of C–F bonds of gem-difluoromethylene derivatives to C–H bonds with lithium aluminum hydride under room temperature

(2010) Jing-Jing Wu et al.   TETRAHEDRON

Expedient Synthesis of N-Fused Indoles: A CF Activation and CH Insertion Approach

(2009) Kohei Fuchibe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Substitution of Allylic Fluorides

(2009) Amaruka Hazari et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Activation of Allylic CF bonds: Palladium-Catalyzed Allylic Amination of 3,3-Difluoropropenes

(2009) Xavier Pigeon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Non-catalytic conversion of C–F bonds of benzotrifluorides to C–C bonds using organoaluminium reagents

(2009) Jun Terao et al.   CHEMICAL COMMUNICATIONS

C−F Bond Activation in Organic Synthesis

(2009) Hideki Amii et al.   CHEMICAL REVIEWS

Brønsted Acid Mediated (sp3)Carbon-Fluorine Bond Activation: Inter- and Intramolecular Arylation of Trifluoromethylated Arenes

(2009) Fei WANG et al.   CHINESE JOURNAL OF CHEMISTRY

Synthesis of Isochromanes and Isothiochromanes Bearing Fluorinated One-Carbon Units via Intramolecular Cyclizations of ortho-Substituted α-(Trifluoromethyl)styrenes

(2009) Junji Ichikawa et al.   HETEROCYCLES

Synthesis of Amide-Type Fluoroalkene Dipeptide Isosteres by an Intramolecular Redox Reaction

(2009) Yoko Yamaki et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Fluoroalkene Dipeptide Isosteres by an Intramolecular Redox Reaction UtilizingN-Heteorocyclic Carbenes (NHCs)

(2009) Yoko Yamaki et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Novel C4-Linked C2-Imidazole Ribonucleoside Phosphoramidite and Its Application to Probing the Catalytic Mechanism of a Ribozyme

(2009) Lisa Araki et al.   JOURNAL OF ORGANIC CHEMISTRY

Carbon−Carbon Coupling of C(sp3)−F Bonds Using Alumenium Catalysis

(2009) Weixing Gu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Peptide bond mimicry by (E)-alkene and (Z)-fluoroalkene peptide isosteres: synthesis and bioevaluation of α-helical anti-HIV peptide analogues

(2009) Shinya Oishi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Gold-Catalyzed Synthesis of 2-Aryl-3-fluoropyrroles

(2009) Riccardo Surmont et al.   ORGANIC LETTERS

C–F Activation of hydrofluorocarbons (HFCs) mediated by aluminum reagents

(2009) Majeid Ali et al.   TETRAHEDRON LETTERS

Update 1 of: Asymmetric Fluorination, Trifluoromethylation, and Perfluoroalkylation Reactions

(2008) Jun-An Ma et al.   CHEMICAL REVIEWS

Synthesis ofgem-Difluoroalkenes via β-Fluoride Elimination of Organorhodium(I)

(2008) Tomoya Miura et al.   CHEMISTRY LETTERS

A New Class of Substrates for Nucleophilic 5-endo-trig Cyclization, 2-Trifluoromethyl-1-alkenes: Synthesis of Five-Membered Hetero- and Carbocycles That Bear Fluorinated One-Carbon Units

(2008) Junji Ichikawa et al.   Chemistry-An Asian Journal

Ring-Opening Reactions of Difluoro(methylene)cyclopropanes with Halogens and Amines

(2008) Xiao-Chun Hang et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of 2,4,5-Trisubstituted 3-Fluorofurans via Sequential Iodocyclization and Cross-Coupling ofgem-Difluorohomopropargyl Alcohols

(2008) Satoru Arimitsu et al.   JOURNAL OF ORGANIC CHEMISTRY

Diastereoselective synthesis of highly functionalized fluoroalkene dipeptide isosteres and its application to Fmoc-based solid-phase synthesis of a cyclic pentapeptide mimetic

(2008) Tetsuo Narumi et al.   TETRAHEDRON

Understanding organofluorine chemistry. An introduction to the C–F bond

(2007) David O'Hagan   CHEMICAL SOCIETY REVIEWS