Cystic fibrosis transmembrane conductance regulator (CFTR): Making an ion channel out of an active transporter structure

ATP Binding Enables Substrate Release from Multidrug Resistance Protein 1

(2018) Zachary Lee Johnson et al.   CELL

Multifaceted structures and mechanisms of ABC transport systems in health and disease

(2018) Christoph Thomas et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Functional organization of cytoplasmic portals controlling access to the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel pore

(2018) Man-Song Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CLC Chloride Channels and Transporters: Structure, Function, Physiology, and Disease

(2018) Thomas J. Jentsch et al.   PHYSIOLOGICAL REVIEWS

Atomic Structure of the Cystic Fibrosis Transmembrane Conductance Regulator

(2016) Zhe Zhang et al.   CELL

The gating of the CFTR channel

(2016) Oscar Moran   CELLULAR AND MOLECULAR LIFE SCIENCES

CFTR pharmacology

(2016) Olga Zegarra-Moran et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Role of CFTR in epithelial physiology

(2016) Vinciane Saint-Criq et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Architecture and functional properties of the CFTR channel pore

(2016) Paul Linsdell   CELLULAR AND MOLECULAR LIFE SCIENCES

Long-range coupling between the extracellular gates and the intracellular ATP binding domains of multidrug resistance protein pumps and cystic fibrosis transmembrane conductance regulator channels

(2016) Shipeng Wei et al.   FASEB JOURNAL

Mechanistic diversity in ATP-binding cassette (ABC) transporters

(2016) Kaspar P Locher   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanistic diversity in ATP-binding cassette (ABC) transporters

(2016) Kaspar P Locher   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cytoplasmic pathway followed by chloride ions to enter the CFTR channel pore

(2015) Yassine El Hiani et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Functional Architecture of the Cytoplasmic Entrance to the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore

(2015) Yassine El Hiani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)

(2015) Valentina Corradi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cysteine accessibility probes timing and extent of NBD separation along the dimer interface in gating CFTR channels

(2015) Luiz A. Poletto Chaves et al.   JOURNAL OF GENERAL PHYSIOLOGY

The Split Personality of Glutamate Transporters: A Chloride Channel and a Transporter

(2015) Rosemary J. Cater et al.   NEUROCHEMICAL RESEARCH

Localizing a gate in CFTR

(2015) Xiaolong Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Full-open and closed CFTR channels, with lateral tunnels from the cytoplasm and an alternative position of the F508 region, as revealed by molecular dynamics

(2014) Jean-Paul Mornon et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Understanding how cystic fibrosis mutations disrupt CFTR function: From single molecules to animal models

(2014) Yiting Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Structural diversity of ABC transporters

(2014) Josy ter Beek et al.   JOURNAL OF GENERAL PHYSIOLOGY

Targeting Multidrug Resistance Protein 1 (MRP1, ABCC1): Past, Present, and Future

(2013) Susan P.C. Cole   Annual Review of Pharmacology and Toxicology

Origin and evolution of the cystic fibrosis transmembrane regulator protein R domain

(2013) Aswathy Sebastian et al.   GENE

Mutagenic Analysis of the Intracellular Portals of the Human 5-HT3A Receptor

(2013) Jane E. Carland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Determinants of coupled transport and uncoupled current by the electrogenic SLC26 transporters

(2011) Ehud Ohana et al.   JOURNAL OF GENERAL PHYSIOLOGY

Mutant cycles at CFTR’s non-canonical ATP-binding site support little interface separation during gating

(2011) Andras Szollosi et al.   JOURNAL OF GENERAL PHYSIOLOGY

Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors)

(2011) D. S. K. Samways et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stable ATP binding mediated by a partial NBD dimer of the CFTR chloride channel

(2010) Ming-Feng Tsai et al.   JOURNAL OF GENERAL PHYSIOLOGY

Molecular models of the open and closed states of the whole human CFTR protein

(2009) Jean-Paul Mornon et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ABC transporters: the power to change

(2009) Douglas C. Rees et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ion channels versus ion pumps: the principal difference, in principle

(2009) David C. Gadsby   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Evolutionary and functional divergence between the cystic fibrosis transmembrane conductance regulator and related ATP-binding cassette transporters

(2008) I. King Jordan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA