Safety and tolerability of LBR-101, a humanized monoclonal antibody that blocks the binding of CGRP to its receptor: Results of the Phase 1 program

Late-Breaking Abstracts of the 2013 International Headache Congress

(2013)   CEPHALALGIA

Clinical Trials Update - 2012: Year in Review

(2013) Stephen J. Peroutka   HEADACHE

Is CGRP a marker for chronic migraine?

(2013) S. D. Silberstein et al.   NEUROLOGY

Interictal increase of CGRP levels in peripheral blood as a biomarker for chronic migraine

(2013) E. Cernuda-Morollon et al.   NEUROLOGY

Emerging Target-Based Paradigms to Prevent and Treat Migraine

(2012) S D Silberstein   CLINICAL PHARMACOLOGY & THERAPEUTICS

CGRP in migraine

(2011) Jes Olesen   CEPHALALGIA

Randomized controlled trial of the CGRP receptor antagonist MK-3207 in the acute treatment of migraine

(2011) David J Hewitt et al.   CEPHALALGIA

New Agents for Acute Treatment of Migraine: CGRP Receptor Antagonists, iNOS Inhibitors

(2011) Jan Hoffmann et al.   Current Treatment Options in Neurology

OnabotulinumtoxinA improves quality of life and reduces impact of chronic migraine

(2011) R. B. Lipton et al.   NEUROLOGY

Pharmacological Properties of MK-3207, a Potent and Orally Active Calcitonin Gene-Related Peptide Receptor Antagonist

(2010) C. A. Salvatore et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Characterization of the Calcitonin Gene-Related Peptide Receptor Antagonist Telcagepant (MK-0974) in Human Isolated Coronary Arteries

(2010) K. Y. Chan et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

New drugs in migraine treatment and prophylaxis: telcagepant and topiramate

(2010) Lars Edvinsson et al.   LANCET

Possible sites of action of the new calcitonin gene-related peptide receptor antagonists

(2010) Sajedeh Eftekhari et al.   Therapeutic Advances in Neurological Disorders

The Acute Treatment of Episodic and Chronic Migraine in the USA

(2009) ME Bigal et al.   CEPHALALGIA

Effects of the prototype serotonin 5-HT1B/1D receptor agonist sumatriptan and the calcitonin gene-related peptide (CGRP) receptor antagonist CGRP8–37 on myocardial reactive hyperemic response in conscious dogs

(2009) Joseph J. Lynch et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Barriers to Satisfactory Migraine Outcomes. What Have We Learned, Where Do We Stand?

(2009) Marcelo Bigal et al.   HEADACHE

Inadequate Dissemination of Phase I Trials: A Retrospective Cohort Study

(2009) Evelyne Decullier et al.   PLOS MEDICINE

CGRP function-blocking antibodies inhibit neurogenic vasodilatation without affecting heart rate or arterial blood pressure in the rat

(2008) J Zeller et al.   BRITISH JOURNAL OF PHARMACOLOGY

Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial

(2008) Tony W Ho et al.   LANCET