New Agents for Acute Treatment of Migraine: CGRP Receptor Antagonists, iNOS Inhibitors

Randomized controlled trial of the CGRP receptor antagonist MK-3207 in the acute treatment of migraine

(2011) David J Hewitt et al.   CEPHALALGIA

Lack of efficacy of the selective iNOS inhibitor GW274150 in prophylaxis of migraine headache

(2010) Hans Olav Høivik et al.   CEPHALALGIA

5-Hydroxyptryptamine 1F (5-HT1F) receptor agonism. A possible new treatment principle for acute migraine attacks

(2010) Jes Olesen   CEPHALALGIA

Preclinical pharmacological profile of the selective 5-HT1F receptor agonist lasmiditan

(2010) David L Nelson et al.   CEPHALALGIA

BI 44370 TA, an oral CGRP antagonist for the treatment of acute migraine attacks: Results from a phase II study

(2010) Hans-Christoph Diener et al.   CEPHALALGIA

Acute treatment of migraine with the selective 5-HT1F receptor agonist lasmiditan – A randomised proof-of-concept trial

(2010) Michel D Ferrari et al.   CEPHALALGIA

Randomized, controlled trial of telcagepant over four migraine attacks

(2010) Andrew P Ho et al.   CEPHALALGIA

Long-Term Tolerability of Telcagepant for Acute Treatment of Migraine in a Randomized Trial

(2010) Kathryn M. Connor et al.   HEADACHE

Antimigraine Efficacy of Telcagepant Based on Patient's Historical Triptan Response

(2010) Tony W. Ho et al.   HEADACHE

Single- and Multiple-Dose Pharmacokinetics and Tolerability of Telcagepant, an Oral Calcitonin Gene-Related Peptide Receptor Antagonist, in Adults

(2010) Tae H. Han et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Characterization of the Calcitonin Gene-Related Peptide Receptor Antagonist Telcagepant (MK-0974) in Human Isolated Coronary Arteries

(2010) K. Y. Chan et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

CGRP and its receptors provide new insights into migraine pathophysiology

(2010) Tony W. Ho et al.   Nature Reviews Neurology

Intravenous aspirin (lysine acetylsalicylate) in the inpatient management of headache

(2010) M. W. Weatherall et al.   NEUROLOGY

Differential distribution of calcitonin gene-related peptide and its receptor components in the human trigeminal ganglion

(2010) S. Eftekhari et al.   NEUROSCIENCE

Nitric oxide-related drag targets in headache

(2010) Jes Olesen   Neurotherapeutics

CGRP receptor antagonism and migraine

(2010) Lars Edvinsson et al.   Neurotherapeutics

The Epidemiology of Primary Headache Disorders

(2010) Matthew Robbins et al.   SEMINARS IN NEUROLOGY

Possible sites of action of the new calcitonin gene-related peptide receptor antagonists

(2010) Sajedeh Eftekhari et al.   Therapeutic Advances in Neurological Disorders

Randomized, controlled trial of telcagepant for the acute treatment of migraine

(2009) K. M. Connor et al.   NEUROLOGY

Calcitonin receptor-like receptor (CLR), receptor activity-modifying protein 1 (RAMP1), and calcitonin gene-related peptide (CGRP) immunoreactivity in the rat trigeminovascular system: Differences between peripheral and central CGRP receptor distribution

(2008) Jochen K. Lennerz et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial

(2008) Tony W Ho et al.   LANCET