Molecular functions and cellular roles of the ChlR1 (DDX11) helicase defective in the rare cohesinopathy Warsaw breakage syndrome

Constitutional Mutations in RTEL1 Cause Severe Dyskeratosis Congenita

(2013) Amanda J. Walne et al.   AMERICAN JOURNAL OF HUMAN GENETICS

An Eco1-independent sister chromatid cohesion establishment pathway in S. cerevisiae

(2013) Vanessa Borges et al.   CHROMOSOMA

Telomere shortening by mutations in theRTEL1helicase cause severe form of dyskeratosis congenita, Hoyerall-Hreidarsson syndrome

(2013) JW Lee   CLINICAL GENETICS

Roles of ChlR1 DNA helicase in replication recovery from DNA damage

(2013) Niyant Shah et al.   EXPERIMENTAL CELL RESEARCH

Germline mutations of regulator of telomere elongation helicase 1, RTEL1, in Dyskeratosis congenita

(2013) Bari J. Ballew et al.   HUMAN GENETICS

Human RTEL1 deficiency causes Hoyeraal–Hreidarsson syndrome with short telomeres and genome instability

(2013) Tangui Le Guen et al.   HUMAN MOLECULAR GENETICS

Specialization among Iron-Sulfur Cluster Helicases to Resolve G-quadruplex DNA Structures That Threaten Genomic Stability

(2013) Sanjay Kumar Bharti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cohesin codes – interpreting chromatin architecture and the many facets of cohesin function

(2013) Soumya Rudra et al.   JOURNAL OF CELL SCIENCE

The Fanconi anemia pathway: Repairing the link between DNA damage and squamous cell carcinoma

(2013) Lindsey E. Romick-Rosendale et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Chl1 DNA Helicase Regulates Scc2 Deposition Specifically during DNA-Replication in Saccharomyces cerevisiae

(2013) Soumya Rudra et al.   PLoS One

Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal–Hreidarsson syndrome

(2013) Zhong Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RTEL1 Is a Replisome-Associated Helicase That Promotes Telomere and Genome-Wide Replication

(2013) J.-B. Vannier et al.   SCIENCE

G-quadruplex structures are stable and detectable in human genomic DNA

(2013) Enid Yi Ni Lam et al.   Nature Communications

Cohesinopathies of a Feather Flock Together

(2013) Robert V. Skibbens et al.   PLoS Genetics

A Recessive Founder Mutation in Regulator of Telomere Elongation Helicase 1, RTEL1, Underlies Severe Immunodeficiency and Features of Hoyeraal Hreidarsson Syndrome

(2013) Bari J. Ballew et al.   PLoS Genetics

Papillomaviruses Use Recombination-Dependent Replication to Vegetatively Amplify Their Genomes in Differentiated Cells

(2013) Nozomi Sakakibara et al.   PLoS Pathogens

Sequence-dependent base pair stepping dynamics in XPD helicase unwinding

(2013) Zhi Qi et al.   eLife

RTEL1 Dismantles T Loops and Counteracts Telomeric G4-DNA to Maintain Telomere Integrity

(2012) Jean-Baptiste Vannier et al.   CELL

Sister chromatid cohesion establishment occurs in concert with lagging strand synthesis

(2012) Soumya Rudra et al.   CELL CYCLE

Setting the stage for cohesion establishment by the replication fork

(2012) Sanjay Kumar Bharti et al.   CELL CYCLE

The ENU-induced cetus mutation reveals an essential role of the DNA helicase DDX11 for mesoderm development during early mouse embryogenesis

(2012) Christina D. Cota et al.   DEVELOPMENTAL DYNAMICS

The Q Motif of Fanconi Anemia Group J Protein (FANCJ) DNA Helicase Regulates Its Dimerization, DNA Binding, and DNA Repair Function

(2012) Yuliang Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shining a Light on Xeroderma Pigmentosum

(2012) John J. DiGiovanna et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The DEAD/DEAH box helicase, DDX11, is essential for the survival of advanced melanomas

(2012) Chitralekha Bhattacharya et al.   Molecular Cancer

Playing the End Game: DNA Double-Strand Break Repair Pathway Choice

(2012) J. Ross Chapman et al.   MOLECULAR CELL

Disease-causing missense mutations in human DNA helicase disorders

(2012) Avvaru N. Suhasini et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

DNA secondary structures: stability and function of G-quadruplex structures

(2012) Matthew L. Bochman et al.   NATURE REVIEWS GENETICS

DNA helicase and helicase-nuclease enzymes with a conserved iron-sulfur cluster

(2012) Y. Wu et al.   NUCLEIC ACIDS RESEARCH

GSK3-SCFFBXW7 targets JunB for degradation in G2 to preserve chromatid cohesion before anaphase

(2012) B Pérez-Benavente et al.   ONCOGENE

Diverse Developmental Disorders from The One Ring: Distinct Molecular Pathways Underlie the Cohesinopathies

(2012) Julia A. Horsfield et al.   Frontiers in Genetics

A history of TFIIH: Two decades of molecular biology on a pivotal transcription/repair factor

(2011) Jean-Marc Egly et al.   DNA REPAIR

CHL-1 provides an essential function affecting cell proliferation and chromosome stability in Caenorhabditis elegans

(2011) George Chung et al.   DNA REPAIR

Regulation of translocation polarity by helicase domain 1 in SF2B helicases

(2011) Robert A Pugh et al.   EMBO JOURNAL

Functional and structural studies of the nucleotide excision repair helicase XPD suggest a polarity for DNA translocation

(2011) Jochen Kuper et al.   EMBO JOURNAL

Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome

(2011) Avvaru N Suhasini et al.   EMBO JOURNAL

Mammalian ChlR1 has a role in heterochromatin organization

(2011) Akira Inoue et al.   EXPERIMENTAL CELL RESEARCH

Biochemical Characterization of Warsaw Breakage Syndrome Helicase

(2011) Yuliang Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer susceptibility variants and the risk of adult glioma in a US case–control study

(2011) Kathleen M. Egan et al.   JOURNAL OF NEURO-ONCOLOGY

Mutations in BRIP1 confer high risk of ovarian cancer

(2011) Thorunn Rafnar et al.   NATURE GENETICS

In vivo analysis of the cell cycle dependent association of the bovine papillomavirus E2 protein and ChlR1

(2011) Katherine M. Feeney et al.   VIROLOGY

Warsaw Breakage Syndrome, a Cohesinopathy Associated with Mutations in the XPD Helicase Family Member DDX11/ChlR1

(2010) Petra van der Lelij et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes

(2010) Y. Wu et al.   BLOOD

Deficiencies in the Fanconi Anemia DNA Damage Response Pathway Increase Sensitivity to HPV-Associated Head and Neck Cancer

(2010) J. W. Park et al.   CANCER RESEARCH

FANCJ: Solving problems in DNA replication

(2010) Kevin Hiom   DNA REPAIR

G-quadruplex nucleic acids and human disease

(2010) Yuliang Wu et al.   FEBS Journal

Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion

(2010) A. R. Leman et al.   JOURNAL OF CELL SCIENCE

Cytogenetic analysis of pediatric anaplastic large cell lymphoma

(2010) Lara Mussolin et al.   PEDIATRIC BLOOD & CANCER

FANCJ Uses Its Motor ATPase to Destabilize Protein-DNA Complexes, Unwind Triplexes, and Inhibit RAD51 Strand Exchange

(2009) Joshua A. Sommers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility

(2009) Margaret Wrensch et al.   NATURE GENETICS

Genome-wide association study identifies five susceptibility loci for glioma

(2009) Sanjay Shete et al.   NATURE GENETICS

Selectivity of small molecule ligands for parallel and anti-parallel DNA G-quadruplex structures

(2009) Thomas P. Garner et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

FANCJ Is a Structure-specific DNA Helicase Associated with the Maintenance of Genomic G/C Tracts

(2008) Timothy B. C. London et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Studies with the Human Cohesin Establishment Factor, ChlR1

(2008) Andrea Farina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FANCJ Helicase Defective in Fanconia Anemia and Breast Cancer Unwinds G-Quadruplex DNA To Defend Genomic Stability

(2008) Y. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Activation of the Cellular DNA Damage Response in the Absence of DNA Lesions

(2008) E. Soutoglou et al.   SCIENCE

RFCCtf18 and the Swi1-Swi3 Complex Function in Separate and Redundant Pathways Required for the Stabilization of Replication Forks to Facilitate Sister Chromatid Cohesion in Schizosaccharomyces pombe

(2007) Alison B. Ansbach et al.   MOLECULAR BIOLOGY OF THE CELL