Circadian clocks and energy metabolism

High-fat diet-induced hyperinsulinemia and tissue-specific insulin resistance in Cry-deficient mice

(2013) Johanna L. Barclay et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

O-GlcNAc Signaling Entrains the Circadian Clock by Inhibiting BMAL1/CLOCK Ubiquitination

(2013) Min-Dian Li et al.   Cell Metabolism

AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation

(2013) Graeme J. Gowans et al.   Cell Metabolism

Glucose Sensor O-GlcNAcylation Coordinates with Phosphorylation to Regulate Circadian Clock

(2013) Krista Kaasik et al.   Cell Metabolism

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

(2013) Estelle Woldt et al.   NATURE MEDICINE

PPARγ signaling and metabolism: the good, the bad and the future

(2013) Maryam Ahmadian et al.   NATURE MEDICINE

Shift Work or Food Intake during the Rest Phase Promotes Metabolic Disruption and Desynchrony of Liver Genes in Male Rats

(2013) Roberto C. Salgado-Delgado et al.   PLoS One

Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT1

(2013) Marina M. Bellet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian acetylome reveals regulation of mitochondrial metabolic pathways

(2013) Selma Masri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Control of Chloroplast Transcription by a Nuclear-Encoded Timing Signal

(2013) Z. B. Noordally et al.   SCIENCE

The diverse roles and clinical relevance of PARPs in DNA damage repair: Current state of the art

(2012) Mike De Vos et al.   BIOCHEMICAL PHARMACOLOGY

Sirtuin activators and inhibitors

(2012) José M. Villalba et al.   BIOFACTORS

Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet

(2012) Megumi Hatori et al.   Cell Metabolism

Circadian Oscillations of Protein-Coding and Regulatory RNAs in a Highly Dynamic Mammalian Liver Epigenome

(2012) Christopher Vollmers et al.   Cell Metabolism

O-GlcNAc Transferase/Host Cell Factor C1 Complex Regulates Gluconeogenesis by Modulating PGC-1α Stability

(2012) Hai-Bin Ruan et al.   Cell Metabolism

Social Jetlag and Obesity

(2012) Till Roenneberg et al.   CURRENT BIOLOGY

Metabolic compensation of the Neurospora clock by a glucose-dependent feedback of the circadian repressor CSP1 on the core oscillator

(2012) G. Sancar et al.   GENES & DEVELOPMENT

Rev-erb  and Rev-erb  coordinately protect the circadian clock and normal metabolic function

(2012) A. Bugge et al.   GENES & DEVELOPMENT

A role for O-GlcNAcylation in setting circadian clock speed

(2012) E. Y. Kim et al.   GENES & DEVELOPMENT

On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1

(2012) X. Luo et al.   GENES & DEVELOPMENT

A Period 2 Genetic Variant Interacts with Plasma SFA to Modify Plasma Lipid Concentrations in Adults with Metabolic Syndrome

(2012) Antonio Garcia-Rios et al.   JOURNAL OF NUTRITION

Dual functions of Insig proteins in cholesterol homeostasis

(2012) Xiao-Ying Dong et al.   Lipids in Health and Disease

AMPK at the crossroads of circadian clocks and metabolism

(2012) Sabine D. Jordan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

(2012) Laura A. Solt et al.   NATURE

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

(2012) Han Cho et al.   NATURE

The sirtuin SIRT6 regulates lifespan in male mice

(2012) Yariv Kanfi et al.   NATURE

linking metabolism to epigenetics through O-GlcNAcylation

(2012) John A. Hanover et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The many faces of insulin-like peptide signalling in the brain

(2012) Ana M. Fernandez et al.   NATURE REVIEWS NEUROSCIENCE

RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo

(2012) Yukimasa Takeda et al.   NUCLEIC ACIDS RESEARCH

Pleiotropic Cellular Functions of PARP1 in Longevity and Aging: Genome Maintenance Meets Inflammation

(2012) Aswin Mangerich et al.   Oxidative Medicine and Cellular Longevity

Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism

(2012) Ruben Nogueiras et al.   PHYSIOLOGICAL REVIEWS

Coordination of the transcriptome and metabolome by the circadian clock

(2012) K. L. Eckel-Mahan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The human circadian metabolome

(2012) R. Dallmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals

(2012) N. Koike et al.   SCIENCE

PPARs: Fatty acid sensors controlling metabolism

(2012) Lars la Cour Poulsen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

PPARs at the crossroads of lipid signaling and inflammation

(2012) Walter Wahli et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Genome-Wide RNA Polymerase II Profiles and RNA Accumulation Reveal Kinetics of Transcription and Associated Epigenetic Changes During Diurnal Cycles

(2012) Gwendal Le Martelot et al.   PLOS BIOLOGY

Nascent-Seq reveals novel features of mouse circadian transcriptional regulation

(2012) Jerome S Menet et al.   eLife

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

(2011) Yu Li et al.   Cell Metabolism

Genome-wide Localization of SREBP-2 in Hepatic Chromatin Predicts a Role in Autophagy

(2011) Young-Kyo Seo et al.   Cell Metabolism

The Circadian Clock Interacts with Metabolic Physiology to Influence Reproductive Fitness

(2011) Kanyan Xu et al.   Cell Metabolism

Fine Tuning Our Cellular Factories: Sirtuins in Mitochondrial Biology

(2011) Lei Zhong et al.   Cell Metabolism

Transcription factors and coactivators controlling nutrient and hormonal regulation of hepatic gluconeogenesis

(2011) Sarawut Jitrapakdee   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Regulation of Fatty Acid Metabolism by Cell Autonomous Circadian Clocks: Time to Fatten up on Information?

(2011) Molly S. Bray et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

O-GlcNAcylation, Novel Post-Translational Modification Linking Myocardial Metabolism and Cardiomyocyte Circadian Clock

(2011) David J. Durgan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interactions between plant circadian clocks and solute transport

(2011) Michael J. Haydon et al.   JOURNAL OF EXPERIMENTAL BOTANY

Genome-Wide Profiling of Liver X Receptor, Retinoid X Receptor, and Peroxisome Proliferator-Activated Receptor   in Mouse Liver Reveals Extensive Sharing of Binding Sites

(2011) M. Boergesen et al.   MOLECULAR AND CELLULAR BIOLOGY

A Global Circadian Repressor Controls Antiphasic Expression of Metabolic Genes in Neurospora

(2011) Gencer Sancar et al.   MOLECULAR CELL

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1

(2011) H.-m. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production

(2011) E. Jing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

(2011) D. Feng et al.   SCIENCE

AMP-activated protein kinase: also regulated by ADP?

(2011) D. Grahame Hardie et al.   TRENDS IN BIOCHEMICAL SCIENCES

Genome-Wide and Phase-Specific DNA-Binding Rhythms of BMAL1 Control Circadian Output Functions in Mouse Liver

(2011) Guillaume Rey et al.   PLOS BIOLOGY

Rotating Night Shift Work and Risk of Type 2 Diabetes: Two Prospective Cohort Studies in Women

(2011) An Pan et al.   PLOS MEDICINE

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

(2010) Shinichi Someya et al.   CELL

The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α

(2010) Lei Zhong et al.   CELL

Poly(ADP-Ribose) Polymerase 1 Participates in the Phase Entrainment of Circadian Clocks to Feeding

(2010) Gad Asher et al.   CELL

PER2 Controls Lipid Metabolism by Direct Regulation of PPARγ

(2010) Benedetto Grimaldi et al.   Cell Metabolism

An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in mice

(2010) L. A. Sadacca et al.   DIABETOLOGIA

The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

(2010) Riekelt H. Houtkooper et al.   ENDOCRINE REVIEWS

Transcription Factors in Light and Circadian Clock Signaling Networks Revealed by Genomewide Mapping of Direct Targets for Neurospora White Collar Complex

(2010) Kristina M. Smith et al.   EUKARYOTIC CELL

The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors

(2010) I. Schmutz et al.   GENES & DEVELOPMENT

Transcriptional repressor TIEG1 regulatesBmal1gene through GC box and controls circadian clockwork

(2010) Tsuyoshi Hirota et al.   GENES TO CELLS

Endogenous Ligands for Nuclear Receptors: Digging Deeper

(2010) Michael Schupp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

(2010) Biliana Marcheva et al.   NATURE

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

(2010) Eric E Zhang et al.   NATURE MEDICINE

Genome-wide analysis of light-inducible responses reveals hierarchical light signalling in Neurospora

(2009) Chen-Hui Chen et al.   EMBO JOURNAL

Nuclear Receptor Liver X Receptor IsO-GlcNAc-modified in Response to Glucose

(2009) Elin Holter Anthonisen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas

(2009) Neil J. McKenna et al.   MOLECULAR ENDOCRINOLOGY

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Delayed fluorescence as a universal tool for the measurement of circadian rhythms in higher plants

(2009) Peter D. Gould et al.   PLANT JOURNAL

Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression

(2009) Christopher Vollmers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adverse metabolic and cardiovascular consequences of circadian misalignment

(2009) F. A. J. L. Scheer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1

(2009) Y. Nakahata et al.   SCIENCE

AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation

(2009) K. A. Lamia et al.   SCIENCE

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis

(2009) K. M. Ramsey et al.   SCIENCE

REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis

(2009) Gwendal Le Martelot et al.   PLOS BIOLOGY

Harmonics of Circadian Gene Transcription in Mammals

(2009) Michael E. Hughes et al.   PLoS Genetics

The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control

(2008) Yasukazu Nakahata et al.   CELL

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

(2008) Gad Asher et al.   CELL

Transcriptional targets of sirtuins in the coordination of mammalian physiology

(2008) Jerome N Feige et al.   CURRENT OPINION IN CELL BIOLOGY

The Orphan Nuclear Receptor, RORα, Regulates Gene Expression That Controls Lipid Metabolism

(2008) Patrick Lau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange

(2008) Yi Liu et al.   NATURE

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

(2008) Xiaoyong Yang et al.   NATURE

Internal desynchronization in a model of night-work by forced activity in rats

(2008) R. Salgado-Delgado et al.   NEUROSCIENCE

A Longitudinal Study on the Effect of Shift Work on Weight Gain in Male Japanese Workers

(2008) Yasushi Suwazono et al.   Obesity

Physiological significance of a peripheral tissue circadian clock

(2008) K. A. Lamia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Occupancy of SREBP1 and Its Partners NFY and SP1 Reveals Novel Functional Roles and Combinatorial Regulation of Distinct Classes of Genes

(2008) Brian D. Reed et al.   PLoS Genetics

Global transcriptome analysis reveals circadian regulation of key pathways in plant growth and development

(2008) Michael F Covington et al.   GENOME BIOLOGY