Elimination of Proliferating Cells Unmasks the Shift from Senescence to Quiescence Caused by Rapamycin

DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence

(2016) Olga V. Leontieva et al.   Aging-US

The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway

(2016) Lioubov G. Korotchkina et al.   Aging-US

Cell cycle arrest is not senescence

(2016) Mikhail V. Blagosklonny   Aging-US

Exploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell culture

(2015) Pasha Apontes et al.   Oncotarget

Rapamycin decelerates cellular senescence

(2011) Zoya N. Demidenko et al.   CELL CYCLE

From growing to secreting: New roles for mTOR in aging cells

(2011) Giovambattista Pani   CELL CYCLE

The power of chemotherapeutic engineering: Arresting cell cycle and suppressing senescence to protect from mitotic inhibitors

(2011) Mikhail V Blagosklonny   CELL CYCLE

Growth stimulation leads to cellular senescence when the cell cycle is blocked

(2010) Zoya N. Demidenko et al.   CELL CYCLE

Weak p53 permits senescence during cell cycle arrest

(2010) Olga V. Leontieva et al.   CELL CYCLE

Paradoxical suppression of cellular senescence by p53

(2010) Z. N. Demidenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY