Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1

A Two-tiered compensatory response to loss of DNA repair modulates aging and stress response pathways

(2016) Øyvind Fensgård et al.   Aging-US

The Replication Checkpoint Protects Fork Stability by Releasing Transcribed Genes from Nuclear Pores

(2011) Rodrigo Bermejo et al.   CELL

Homozygous deficiency of ubiquitin-ligase ring-finger protein RNF168 mimics the radiosensitivity syndrome of ataxia-telangiectasia

(2011) S S Devgan et al.   CELL DEATH AND DIFFERENTIATION

Replication stress induces 53BP1-containing OPT domains in G1 cells

(2011) Jeanine A. Harrigan et al.   JOURNAL OF CELL BIOLOGY

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

(2011) Claudia Lukas et al.   NATURE CELL BIOLOGY

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

(2011) Jiri Lukas et al.   NATURE CELL BIOLOGY

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

(2010) Samuel F. Bunting et al.   CELL

Regulation of the ATM-activator protein Aven by CRM1-dependent nuclear export

(2010) Armond M. Esmaili et al.   CELL CYCLE

The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks

(2010) Asako J. Nakamura et al.   CELL CYCLE

ATM-dependent expression of IEX-1 controls nuclear accumulation of Mcl-1 and the DNA damage response

(2010) P Pawlikowska et al.   CELL DEATH AND DIFFERENTIATION

Nuclear initiated NF-κB signaling: NEMO and ATM take center stage

(2010) Shigeki Miyamoto   CELL RESEARCH

BRCA1 16 years later: nuclear import and export processes

(2010) Marilyn E. Thompson   FEBS Journal

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome

(2010) Heinz Neumann et al.   NATURE

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

(2010) Peter Bouwman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CCAAT/enhancer binding protein delta (C/EBP , CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage

(2010) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

(2009) Grant S. Stewart et al.   CELL

53BP1 represses mitotic catastrophe in syncytia elicited by the HIV-1 envelope

(2009) J-L Perfettini et al.   CELL DEATH AND DIFFERENTIATION

Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-α3 binding

(2009) N D Marchenko et al.   CELL DEATH AND DIFFERENTIATION

The Ins and Outs of Nuclear Trafficking: Unusual Aspects in Apicomplexan Parasites

(2009) Matthew B. Frankel et al.   DNA AND CELL BIOLOGY

Cellular Redistribution of Rad51 in Response to DNA Damage

(2009) Otto S. Gildemeister et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Nucleoporin Nup153 Has Separable Roles in Both Early Mitotic Progression and the Resolution of Mitosis

(2009) Douglas R. Mackay et al.   MOLECULAR BIOLOGY OF THE CELL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Nuclear pore complex assembly through the cell cycle: Regulation and membrane organization

(2008) Wolfram Antonin et al.   FEBS LETTERS

Dif1 Is a DNA-Damage-Regulated Facilitator of Nuclear Import for Ribonucleotide Reductase

(2008) Yang David Lee et al.   MOLECULAR CELL

Individual binding pockets of importin-  for FG-nucleoporins have different binding properties and different sensitivities to RanGTP

(2008) S. Otsuka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE

Functional Targeting of DNA Damage to a Nuclear Pore-Associated SUMO-Dependent Ubiquitin Ligase

(2008) S. Nagai et al.   SCIENCE