Homozygous deficiency of ubiquitin-ligase ring-finger protein RNF168 mimics the radiosensitivity syndrome of ataxia-telangiectasia

Microdeletions of 3q29 Confer High Risk for Schizophrenia

(2010) Jennifer Gladys Mulle et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Autistic and psychiatric findings associated with the 3q29 microdeletion syndrome: Case report and review

(2010) Fabiola Quintero-Rivera et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

SUMO Boosts the DNA Damage Response Barrier against Cancer

(2010) Jiri Bartek et al.   CANCER CELL

Atm-Deficient Mice Exhibit Increased Sensitivity to Dextran Sulfate Sodium-Induced Colitis Characterized by Elevated DNA Damage and Persistent Immune Activation

(2010) A. M. Westbrook et al.   CANCER RESEARCH

The ubiquitous role of ubiquitin in the DNA damage response

(2010) Abdallah Al-Hakim et al.   DNA REPAIR

Population Analysis of Large Copy Number Variants and Hotspots of Human Genetic Disease

(2009) Andy Itsara et al.   AMERICAN JOURNAL OF HUMAN GENETICS

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

(2009) Grant S. Stewart et al.   CELL

DNA double strand break repair defects, primary immunodeficiency disorders, and ‘radiosensitivity’

(2009) Shareef A Nahas et al.   Current Opinion in Allergy and Clinical Immunology

Clinical Radiation Sensitivity With DNA Repair Disorders: An Overview

(2009) Julianne M. Pollard et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress

(2009) Joanna R. Morris et al.   NATURE

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

(2009) Yaron Galanty et al.   NATURE

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

(2009) Simon Bekker-Jensen et al.   NATURE CELL BIOLOGY

Common Variable Immunodeficiency

(2009) Francisco A Bonilla et al.   PEDIATRIC RESEARCH

The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination

(2009) S. Ramachandran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleic acid-mediated inflammatory diseases

(2008) Rachel E. Rigby et al.   BIOESSAYS

Hereditary breast cancer: from molecular pathology to tailored therapies

(2008) D S P Tan et al.   JOURNAL OF CLINICAL PATHOLOGY

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE