Review
Chemistry, Applied
Tiina Nypelo, Barbara Berke, Stefan Spirk, Juho Antti Sirvio
Summary: The periodate oxidation of polysaccharides has evolved from structural analysis to a modification method for engineered materials, with potential applications in crosslinking and functional group generation. This process leads to changes in the structural hierarchies and physical properties of materials derived from forests, providing opportunities for further modifications and enhanced functionalities.
CARBOHYDRATE POLYMERS
(2021)
Article
Materials Science, Paper & Wood
Saul Llacer Navarro, Koyuru Nakayama, Alexander Idstrom, Lars Evenas, Anna Strom, Tiina Nypelo
Summary: The influence of sulfate half-ester group on the oxidation of cellulose nanocrystals (CNCs) was studied, revealing its role in regulating oxidation kinetics and properties of resulting materials. The presence of sulfate half-ester group decreases oxidation rate, but decreases in content as oxidation degree reaches approximately 50%. Furthermore, the surfaces of CNCs are affected by oxidation beyond C2-C3 bond cleavage, underscoring the importance of understanding kinetics for optimizing CNC oxidation.
Article
Green & Sustainable Science & Technology
Ting Yang, Peiwen Liu, Dan Xu, Jiaxiu Wang, Kai Zhang
Summary: Cellulose nanofibers (PO-CNFs) and cellulose nanocrystals (PO-CNCs) are directly prepared from native softwood spruce and hardwood beech using the same alkaline periodate oxidation. These nanocelluloses, containing carboxy groups, exhibit good colloidal stability in water and can be used to form highly transparent films with good mechanical properties. The nanocellulose content isolated from the spruce and beech increases with reaction time, reaching optimal levels after 7 days of oxidation.
ADVANCED SUSTAINABLE SYSTEMS
(2021)
Review
Food Science & Technology
Long Bai, Siqi Huan, Ya Zhu, Guang Chu, David Julian McClements, Orlando J. Rojas
Summary: This article reviews the application of nanocelluloses, such as cellulose nanofibrils and cellulose nanocrystals, as functional ingredients in foods. These ingredients can alter the physicochemical, sensory, and nutritional properties of foods and create novel structures. By extending their functionality through chemical modification or combining with other natural food ingredients, nanocelluloses can be used to create stimuli-responsive and active functional biomaterials for various food applications.
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 12, 2021
(2021)
Article
Biochemistry & Molecular Biology
Bruno Las-Casas, Isabella K. R. Dias, Sergio Luis Yupanqui-Mendoza, Barbara Pereira, Guilherme R. Costa, Orlando J. Rojas, Valdeir Arantes
Summary: This article summarizes the unique properties and environmental benefits of cellulose nanomaterials (CNs), with a focus on cellulose nanofibrils (CNFs) and nanocrystals (CNCs), which are the most extensively researched types of CNs. The authors propose hybrid cellulose nanomaterials (HCNs) as the standardized classification for these materials and comprehensively examine their potential and performance in various applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Nassima El Miri, Ellinor Baevre Heggset, Sara Wallsten, Anna Svedberg, Kristin Syverud, Magnus Norgren
Summary: This study aimed to modulate the properties of cellulose nanocrystals (CNCs) by introducing different functional groups on the surface through various chemical modifications. The results showed that the properties of CNCs varied depending on the grafted functionalities. Interestingly, the modifications maintained colloidal stability and improved thermal stability and oxygen barrier properties.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Materials Science, Paper & Wood
Qichao Fan, Bencai Lin, Yu Nie, Qing Sun, Wenxiang Wang, Liangjiu Bai, Hou Chen, Lixia Yang, Huawei Yang, Donglei Wei
Summary: Nanocomposite hydrogels with self-healing performance were proposed by introducing binary solvents and dual self-healing interactions, preventing ice crystal formation and enhancing flexibility and self-healing abilities of hydrogels in subzero environment. The obtained hydrogels showed improved mechanical properties and self-healing efficiencies, with rupture stress of 0.24 MPa, rupture strain of 1900%, and healing efficiency of up to 80.1% at -20 degrees C, indicating broader potential applications in subzero environment.
Article
Materials Science, Paper & Wood
Chengpeng Shen, Chuanshuang Hu, Weiwei Zhang, Xiuyi Lin, Wei Qi, Zhen Zhang, Jin Gu
Summary: This study explored environmentally friendly and cost-effective methods for producing nanocelluloses with controllable morphology. By treating microcrystalline cellulose with acidified zinc chloride molten salt hydrates, rod and sphere-shaped cellulose I and II nanocrystals were obtained. The levels of cellulose swelling and hydrolysis could be controlled by adjusting the concentration of HCl and ZnCl2. The resulting nanocelluloses exhibited different sizes and properties, with improved crystallinity and thermal stability observed at higher HCl concentrations. The spherical nanocellulose II showed excellent suspension stability and emulsifying ability to stabilize oil/water Pickering emulsions. This study provides a sustainable method for producing nanocelluloses with tailored characteristics and broad application potentials.
Review
Polymer Science
Abd Ghafar Nurhanis Sofiah, Jagadeesh Pasupuleti, Mahendran Samykano, Kumaran Kadirgama, Siaw Paw Koh, Sieh Kieh Tiong, Adarsh Kumar Pandey, Chong Tak Yaw, Sendhil Kumar Natarajan
Summary: This article provides a comprehensive overview of nanocellulose preparation methods, structure-property correlations, and applications. Nanocellulose is a renewable and sustainable material with tunable surface properties and biocompatibility. The article discusses the classification and production methods of nanocellulose, highlights its unique properties derived from experiments and studies, and elaborates on its potential applications in various areas.
Article
Chemistry, Applied
Rui-jing Qu, Yong Wang, Dong Li, Li-jun Wang
Summary: This study investigated the influence of calcium chloride (CaCl2) concentration on the properties of nanocellulose gels, showing that the absolute zeta potential decreased as CaCl2 concentration increased, leading to improved rheological properties. The enhanced gel network structure was attributed to the crosslinking promotion between nanocellulose by Ca2+ ions, demonstrating the tunability of rheological behavior by adjusting the concentration of CaCl2.
CARBOHYDRATE POLYMERS
(2021)
Review
Chemistry, Multidisciplinary
Katja Heise, Eero Kontturi, Yagut Allahverdiyeva, Tekla Tammelin, Markus B. Linder, Nonappa, Olli Ikkala
Summary: Nanocelluloses have attracted significant attention in the pursuit of sustainable advanced functional materials. Despite facing challenges in mastering their interactions and tailorability, recent progress in water interactions and advanced hybrid gels has opened up new directions for potential applications like nanocomposites, gels, and composite fibers.
ADVANCED MATERIALS
(2021)
Review
Chemistry, Applied
Qianqian Wang, Simeng Liu, Jun Liu, Jianzhong Sun, Zhen Zhang, Qianqian Zhu
Summary: CNMs membranes, as a novel membrane material based on green resources and sustainable processes, have great potential in environmental remediation. Understanding the interactions between CNMs and different substances, as well as their selective transport mechanisms in membrane separation processes, is crucial for their practical applications.
CARBOHYDRATE POLYMERS
(2022)
Article
Nanoscience & Nanotechnology
Lu Tang, Jing Liao, Hongjie Dai, Yushan Liu, Huihua Huang
Summary: The study produced pineapple cellulose nanocrystals (PCNCs) from different sections of pineapple through sulfuric acid hydrolysis, and found variations in crystallinity and thermal stability among PCNCs from pineapple core, pulp, leaf, and peel, which also affected the stability of the Pickering emulsions.
Review
Nanoscience & Nanotechnology
Wei Liu, Kun Liu, Haishun Du, Ting Zheng, Ning Zhang, Ting Xu, Bo Pang, Xinyu Zhang, Chuanling Si, Kai Zhang
Summary: This article summarizes and discusses the recent progress in the fabrication and applications of cellulose nanopaper, including the characteristics of various types of nanocellulose, preparation methods, and their applications in different fields.
NANO-MICRO LETTERS
(2022)
Article
Materials Science, Composites
Thi Vi Vi Do, Ngoc Bao An Tran, Ngoc Uyen Nguyen-Thai
Summary: This study extracted spherical cellulose nanocrystals from Gai bamboo fibers through sulfuric acid hydrolysis methods. The changes in bond's vibration and thermogravimetric diagram indicated the removal of amorphous components, lignin, and hemicellulose in the raw bamboo fiber and the incorporation of sulfate groups. The nanocellulose exhibited a spherical shape with a diameter of 2 to 10 nm, a crystallization index of 70.30%, and a crystallization degree of 0.77. The chitosan films loaded with spherical nanocellulose showed improved thermal and mechanical properties, including increased tensile strength, modulus, elongation at break, and decreased moisture absorption.
POLYMER COMPOSITES
(2023)
Article
Chemistry, Physical
Elina Niinivaara, Johanna Desmaisons, Alain Dufresne, Julien Bras, Emily D. Cranston
Summary: SIEBIMM is a high throughput, easy to use, and accurate method for characterizing the Young's modulus of coatings, suitable for various environments. Experimental findings show that SIEBIMM can accurately characterize coatings up to 35 mm thick, requiring consistent measurement of coating thickness and wavelength for thicker coatings to minimize errors.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Biophysics
Fatma Ben Cheikh, Ayman Ben Mabrouk, Albert Magnin, Jean-Luc Putaux, Sami Boufi
Summary: Chitin nanocrystals were used as stabilizing agent for oil-in-water emulsification, leading to emulsions with low droplet size and long-term stability. This opens new avenues for producing emulsions for a wide variety of applications.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Biochemistry & Molecular Biology
Fatma Ben Cheikh, Ayman Ben Mabrouk, Albert Magnin, Christine Lancelon-Pin, Jean-Luc Putaux, Sami Boufi
Summary: Stable biobased waterborne Pickering dispersions were developed using chitin nanocrystals as the sole emulsifier, without any additives. The inclusion of ChNCs was found to significantly increase the stiffness and strength of the cured films without compromising their optical transparency. This offers new opportunities for the production of waterborne stable dispersions from AESO for biobased coatings and adhesives.
Article
Polymer Science
Ge Zhu, Laura Giraldo Isaza, Alain Dufresne
Summary: A green and powerful strategy for preparing CNC/GO/NR nanocomposites with a 3D hierarchical conductive network was reported. The CNC/GO nanohybrids, with enhanced stability due to hydrogen bonding interactions, significantly improved electrical conductivity and mechanical properties of the nanocomposites. The nanocomposite with 4 wt% GO and 5 wt% CNC exhibited a nine orders of magnitude increase in electrical conductivity compared to the nanocomposite with only 4 wt% GO.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Nanoscience & Nanotechnology
Elina Niinivaara, Johanna Desmaisons, Alain Dufresne, Julien Bras, Emily D. Cranston
Summary: The SIEBIMM method was used to quantify the Young's modulus of PVOH coatings reinforced with CNCs, showing a 13-fold increase in modulus due to factors such as CNC forming a percolated network, compatibility between CNCs and PVOH, and CNCs nucleating PVOH crystallites. Higher drying temperatures and lower relative humidity improved mechanical performance of CNC/PVOH coatings, increasing the modulus by 6 times compared to neat PVOH.
ACS APPLIED NANO MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Ge Zhu, Laura Giraldo Isaza, Bai Huang, Alain Dufresne
Summary: Aerogels made from nano-cellulose and carbon nanotubes have been developed as a promising solution for shielding electromagnetic interference, with characteristics such as lightweight, highly porous, conductive, mechanically resistant properties. The aerogels show great potential to be used as green and lightweight shielding elements against electromagnetic radiation, given their density below 0.075 g/cm(3), porosity over 95.47%, conductivity up to 26.2 S/m.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Materials Science, Multidisciplinary
Meng Zhang, Xiao Fan, Weijie Guo, Haijun Zhou, Zhaolei Li, Yu Ma, Chao Yan, Alain Dufresne
Summary: This study investigates the structural evolution and interaction between enantiomeric chains in the crystallization of poly(lactic acid) (PLA) racemic blends using commercial fast-scan chip calorimetry. The results show that the 10(3) helices always emerge first after cooling the racemic melt, followed by a transformation into 3(1) helices triggered by the interaction between the enantiomeric chains. This provides a physical basis for studying the competition between stereocomplex crystals (SC) and homocrystals (HC) in PLA, as well as a theoretical foundation for the preparation of biodegradable engineering plastics.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Materials Science, Textiles
Salah Amroune, Abderrezak Bezazi, Alain Dufresne, Fabrizio Scarpa, Abdellatif Imad
Summary: Date palm fibers were studied as potential reinforcement in composite materials. Their mechanical properties were determined through quasi-static tensile tests and cyclic fiber fatigue tests. The results showed that considering the porosity improved the mechanical properties of the fibers significantly.
JOURNAL OF NATURAL FIBERS
(2022)
Article
Materials Science, Textiles
Riyadh Benyettou, Salah Amroune, Slamani Mohamed, Yasemin Seki, Alain Dufresne
Summary: The present study investigates the water absorption properties of bio-composites reinforced with date palm fibers. It was found that the water absorption rate increases with increasing fiber content. Scanning electron microscopy and image J software were used to understand the absorption phenomenon and determine the porosity rate. Artificial neural network method was also employed to predict the absorption rate.
JOURNAL OF NATURAL FIBERS
(2022)
Article
Materials Science, Multidisciplinary
Riyadh Benyettou, Salah Amroune, Mohamed Slamani, Yasemin Seki, Alain Dufresne, Mohammad Jawaid, Salman Alamery
Summary: This study focuses on the drilling performance of bio composites reinforced with date palm fibers. Experimental results showed that the delamination factor increased with the increase in feed rate and decreased with the increase in spindle speed. The use of RSM and ANOVA allowed to assess the influence and interaction of cutting conditions on the delamination factor during drilling.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Article
Chemistry, Multidisciplinary
Lei Tan, Alain Dufresne, Ge Zhu, Ning Lin
Summary: Receiving considerable interest in recent years, the reducing ends of cellulose nanocrystals (CNCs) have different reactivity from surface chemistry, which contributes to the development of new strategies for modification and performance tailoring. However, the understanding of the phenomena involved at the reducing end is still limited for nanocrystals. This study explores the introduction of aldehyde groups at the reducing end and investigates the influence of the modified species on the crystalline reconfiguration of nanocrystals.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Multidisciplinary Sciences
Mohamed H. Hemida, Hesham Moustafa, Sherif Mehanny, Mohamed Morsy, Alain Dufresne, Eid N. Abd E. L. Rahman, M. M. Ibrahim
Summary: This study evaluated Nile roses fibers as a natural biomass for the extraction of cellulose nanocrystals (CNCs) through acid hydrolysis. The impact of extraction duration on the morphology and crystallinity of prepared CNCs was investigated, and various characterization techniques were used. The results showed that a 20-minute acid hydrolysis duration yielded an optimized fibrillar structure.
Article
Chemistry, Physical
Hesham Moustafa, Mohamed H. Hemida, Mohamed A. Shemis, Alain Dufresne, Mohamed Morsy
Summary: This study presents a highly efficient humidity sensing material based on folic acid (FA) functionalized graphene oxide (GO) embedded in a chitosan (CS)/polyvinyl alcohol (PVA) matrix. The nanosensors with various GO-FA contents were fabricated and characterized for their morphology, tensile strength, Raman spectroscopy, antibacterial activities, and humidity sensing properties. The sensor C10, with 10% GO-FA content, exhibited the highest sensitivity and ultrafast response/recovery times (2.6 s/3.5 s), making it suitable for intelligent food packaging and preservation.
SURFACES AND INTERFACES
(2023)
Review
Chemistry, Multidisciplinary
Alain Dufresne
Summary: The interest in materials from biological resources has grown tremendously in recent years due to their potential to manufacture high value products with low environmental impact. This article reviews the preparation of nanomaterials from cellulose and explores the promising markets where cellulose nanomaterials can find applications.
CHEMISTRY AFRICA-A JOURNAL OF THE TUNISIAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Physical
Bai Huang, Ge Zhu, Shuzhan Wang, Qunyang Li, Jeremie Viguie, Hui He, Alain Dufresne
Summary: A simple interface co-precipitation strategy is proposed for the preparation of polymer/polysaccharide composite actuators, resulting in actuators with rapid deformation, high tensile strength, and toughness. The prepared actuators exhibit controllable three-dimensional deformability and can be used in applications such as bionic flowers.
JOURNAL OF MATERIALS CHEMISTRY A
(2021)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)