Genetic and non-genetic instability in tumor progression: link between the fitness landscape and the epigenetic landscape of cancer cells
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Genetic and non-genetic instability in tumor progression: link between the fitness landscape and the epigenetic landscape of cancer cells
Authors
Keywords
Gene instability non-genetic heterogeneity, Cancer stem cell, Cancer attractor, Plasticity, Epigenetic landscape
Journal
CANCER AND METASTASIS REVIEWS
Volume 32, Issue 3-4, Pages 423-448
Publisher
Springer Nature
Online
2013-05-02
DOI
10.1007/s10555-013-9435-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Defining the molecular response to trastuzumab, pertuzumab and combination therapy in ovarian cancer
- (2012) A H Sims et al. BRITISH JOURNAL OF CANCER
- Quasi-potential landscape in complex multi-stable systems
- (2012) J. X. Zhou et al. Journal of the Royal Society Interface
- Maintaining differentiated cellular identity
- (2012) Johan Holmberg et al. NATURE REVIEWS GENETICS
- Evolution of the cancer genome
- (2012) Lucy R. Yates et al. NATURE REVIEWS GENETICS
- Ionizing Radiation Induces Stemness in Cancer Cells
- (2012) Laura Ghisolfi et al. PLoS One
- Tumor progression: Chance and necessity in Darwinian and Lamarckian somatic (mutationless) evolution
- (2012) Sui Huang PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer
- (2012) A. Kreso et al. SCIENCE
- Bacterial survival strategies suggest rethinking cancer cooperativity
- (2012) Eshel Ben-Jacob et al. TRENDS IN MICROBIOLOGY
- Criticality Is an Emergent Property of Genetic Networks that Exhibit Evolvability
- (2012) Christian Torres-Sosa et al. PLoS Computational Biology
- Thermogenesis, muscle hyperplasia, and the origin of birds
- (2011) Stuart A. Newman BIOESSAYS
- The molecular and mathematical basis of Waddington's epigenetic landscape: A framework for post-Darwinian biology?
- (2011) Sui Huang BIOESSAYS
- Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development
- (2011) Philip J. Stephens et al. CELL
- Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
- (2011) Piyush B. Gupta et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Origins and consequences of transcriptional discontinuity
- (2011) David M Suter et al. CURRENT OPINION IN CELL BIOLOGY
- Overcoming tumor multidrug resistance using drugs able to evade P-glycoprotein or to exploit its expression
- (2011) Stefania Nobili et al. MEDICINAL RESEARCH REVIEWS
- The proliferation rate paradox in antimitotic chemotherapy
- (2011) Timothy J. Mitchison MOLECULAR BIOLOGY OF THE CELL
- Systems biology of stem cells: three useful perspectives to help overcome the paradigm of linear pathways
- (2011) S. Huang PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Phenotypic heterogeneity and instability of human ovarian tumor-initiating cells
- (2011) J. M. Stewart et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
- (2011) C. L. Chaffer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- On the intrinsic inevitability of cancer: From foetal to fatal attraction
- (2011) Sui Huang SEMINARS IN CANCER BIOLOGY
- Bcl9/Bcl9l Are Critical for Wnt-Mediated Regulation of Stem Cell Traits in Colon Epithelium and Adenocarcinomas
- (2010) J. Deka et al. CANCER RESEARCH
- A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
- (2010) Sreenath V. Sharma et al. CELL
- A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth
- (2010) Alexander Roesch et al. CELL
- Cellular Heterogeneity: Do Differences Make a Difference?
- (2010) Steven J. Altschuler et al. CELL
- Involvement of NF-κB/miR-448 regulatory feedback loop in chemotherapy-induced epithelial–mesenchymal transition of breast cancer cells
- (2010) Q-Q Li et al. CELL DEATH AND DIFFERENTIATION
- Stochastic acquisition of a stem cell-like state and drug tolerance in leukemia cells stressed by radiation
- (2010) Ga-Young Lee et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Neo-Darwinism, the Modern Synthesis and selfish genes: are they of use in physiology?
- (2010) Denis Noble JOURNAL OF PHYSIOLOGY-LONDON
- Cancer stem cells: Invitation to a second round
- (2010) Peter Dirks NATURE
- Functional roles for noise in genetic circuits
- (2010) Avigdor Eldar et al. NATURE
- Genomic instability — an evolving hallmark of cancer
- (2010) Simona Negrini et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
- (2010) A Singh et al. ONCOGENE
- Cancer stem cells versus phenotype-switching in melanoma
- (2010) Keith S. Hoek et al. Pigment Cell & Melanoma Research
- Efficiency of carcinogenesis: Is the mutator phenotype inevitable?
- (2010) Robert A. Beckman SEMINARS IN CANCER BIOLOGY
- Cell Lineage Determination in State Space: A Systems View Brings Flexibility to Dogmatic Canonical Rules
- (2010) Sui Huang PLOS BIOLOGY
- An Extended Synthesis for Evolutionary Biology
- (2009) Massimo Pigliucci Annals of the New York Academy of Sciences
- Evolutionary Theory of Cancer
- (2009) Camille Stephan-Otto Attolini et al. Annals of the New York Academy of Sciences
- Putting together the pieces: evolutionary mechanisms at work within genomes
- (2009) Lynn Helena Caporale BIOESSAYS
- Reprogramming cell fates: reconciling rarity with robustness
- (2009) Sui Huang BIOESSAYS
- Acquisition of Epithelial-Mesenchymal Transition Phenotype of Gemcitabine-Resistant Pancreatic Cancer Cells Is Linked with Activation of the Notch Signaling Pathway
- (2009) Z. Wang et al. CANCER RESEARCH
- Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer
- (2009) T. Arumugam et al. CANCER RESEARCH
- Cancer Stem Cells: Controversial or Just Misunderstood?
- (2009) Craig T. Jordan Cell Stem Cell
- Twist1-Mediated Adriamycin-Induced Epithelial-Mesenchymal Transition Relates to Multidrug Resistance and Invasive Potential in Breast Cancer Cells
- (2009) Q.-Q. Li et al. CLINICAL CANCER RESEARCH
- Non-genetic heterogeneity of cells in development: more than just noise
- (2009) S. Huang DEVELOPMENT
- Optimization aspects of carcinogenesis
- (2009) B. Brutovsky et al. MEDICAL HYPOTHESES
- Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
- (2009) Sabrina L. Spencer et al. NATURE
- A comprehensive catalogue of somatic mutations from a human cancer genome
- (2009) Erin D. Pleasance et al. NATURE
- Cancer stem cells: mirage or reality?
- (2009) Piyush B Gupta et al. NATURE MEDICINE
- Non-genetic heterogeneity — a mutation-independent driving force for the somatic evolution of tumours
- (2009) Amy Brock et al. NATURE REVIEWS GENETICS
- Cancer attractors: A systems view of tumors from a gene network dynamics and developmental perspective
- (2009) Sui Huang et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences
- (2008) Arjun Raj et al. CELL
- Epithelial mesenchymal transition traits in human breast cancer cell lines
- (2008) T. Blick et al. CLINICAL & EXPERIMENTAL METASTASIS
- Transcriptome-wide noise controls lineage choice in mammalian progenitor cells
- (2008) Hannah H. Chang et al. NATURE
- Critical Dynamics in Genetic Regulatory Networks: Examples from Four Kingdoms
- (2008) Enrique Balleza et al. PLoS One
- Dynamic Proteomics of Individual Cancer Cells in Response to a Drug
- (2008) A. A. Cohen et al. SCIENCE
- Transitions between epithelial and mesenchymal states in development and disease
- (2008) Buzz Baum et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- How transcription factors program chromatin—Lessons from studies of the regulation of myeloid-specific genes
- (2008) Constanze Bonifer et al. SEMINARS IN IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started