Mitochondria: a multimodal hub of hypoxia tolerance

Breathing nitric oxide plus hydrogen gas reduces ischemia-reperfusion injury and nitrotyrosine production in murine heart

(2013) Toshihiro Shinbo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mitochondrial reactive oxygen species: which ROS signals cardioprotection?

(2013) Anders O. Garlid et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Beating oxygen: chronic anoxia exposure reduces mitochondrial F1FO-ATPase activity in turtle (Trachemys scripta) heart

(2013) G. L. J. Galli et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Anoxia-mediated calcium release through the mitochondrial permeability transition pore silences NMDA receptor currents in turtle neurons

(2013) P. J. Hawrysh et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Oxygen-sensitive reduction in Ca2+-activated K+ channel open probability in turtle cerebrocortex

(2013) C.I. Rodgers-Garlick et al.   NEUROSCIENCE

Preconditioning the Human Brain

(2013) Sebastian Koch et al.   STROKE

The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage

(2013) H Bradley Shaffer et al.   GENOME BIOLOGY

Mitochondrial permeability transition pore as a selective target for anti-cancer therapy

(2013) Dong H. Suh et al.   Frontiers in Oncology

Neuroprotection against hypoxia/ischemia: δ-opioid receptor-mediated cellular/molecular events

(2012) Xiaozhou He et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Physiological Roles of the Permeability Transition Pore

(2012) Catherine Brenner et al.   CIRCULATION RESEARCH

Mitochondrial ATP-sensitive potassium channel activity and hypoxic preconditioning are independent of an inwardly rectifying potassium channel subunit inCaenorhabditis elegans

(2012) Andrew P. Wojtovich et al.   FEBS LETTERS

Painted Turtle Cortex is Resistant to an in Vitro Mimic of the Ischemic Mammalian Penumbra

(2012) Matthew Edward Pamenter et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The yak genome and adaptation to life at high altitude

(2012) Qiang Qiu et al.   NATURE GENETICS

Mitochondrial Ca2+ homeostasis: mechanism, role, and tissue specificities

(2012) Paola Pizzo et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2

(2012) Nanduri R. Prabhakar et al.   PHYSIOLOGICAL REVIEWS

Blunted Neuronal Calcium Response to Hypoxia in Naked Mole-Rat Hippocampus

(2012) Bethany L. Peterson et al.   PLoS One

Hypoxia-Adaptation Involves Mitochondrial Metabolic Depression and Decreased ROS Leakage

(2012) Sameh S. Ali et al.   PLoS One

DIDS Prevents Ischemic Membrane Degradation in Cultured Hippocampal Neurons by Inhibiting Matrix Metalloproteinase Release

(2012) Matthew E. Pamenter et al.   PLoS One

Autophagy and Apoptosis Are Differentially Induced in Neurons and Astrocytes Treated with an In Vitro Mimic of the Ischemic Penumbra

(2012) Matthew E. Pamenter et al.   PLoS One

Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation

(2012) A. M. Nargund et al.   SCIENCE

The ER–mitochondria interface: The social network of cell death

(2011) Stefan Grimm   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

After half a century mitochondrial calcium in- and efflux machineries reveal themselves

(2011) Ilaria Drago et al.   EMBO JOURNAL

Oxidative stress, mitochondrial permeability transition pore opening and cell death during hypoxia–reoxygenation in adult cardiomyocytes

(2011) Rana Assaly et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The role of free radical generation in increasing cerebrovascular permeability

(2011) Paul A. Fraser   FREE RADICAL BIOLOGY AND MEDICINE

AMP-activated protein kinase plays a role in initiating metabolic rate suppression in goldfish hepatocytes

(2011) Gigi Y. Lau et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

A radical approach to beating hypoxia: depressed free radical release from heart fibres of the hypoxia-tolerant epaulette shark (Hemiscyllum ocellatum)

(2011) Anthony J. R. Hickey et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

Genome sequencing reveals insights into physiology and longevity of the naked mole rat

(2011) Eun Bae Kim et al.   NATURE

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

(2011) Joshua M. Baughman et al.   NATURE

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

(2011) Diego De Stefani et al.   NATURE

AMP-activated protein kinase: nature's energy sensor

(2011) David Carling et al.   Nature Chemical Biology

Adult naked mole-rat brain retains the NMDA receptor subunit GluN2D associated with hypoxia tolerance in neonatal mammals

(2011) Bethany L. Peterson et al.   NEUROSCIENCE LETTERS

Oxygen Sensing, Homeostasis, and Disease

(2011) Gregg L. Semenza   NEW ENGLAND JOURNAL OF MEDICINE

Endogenous GABAA and GABAB receptor-mediated electrical suppression is critical to neuronal anoxia tolerance

(2011) M. E. Pamenter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redox Control of Protein–DNA Interactions: From Molecular Mechanisms to Significance in Signal Transduction, Gene Expression, and DNA Replication

(2010) Joseph Shlomai   ANTIOXIDANTS & REDOX SIGNALING

Redox Control in Mammalian Embryo Development

(2010) Christoph Ufer et al.   ANTIOXIDANTS & REDOX SIGNALING

Molecular and cellular mechanisms of excitotoxic neuronal death

(2010) Yan Wang et al.   APOPTOSIS

A pore way to die: the role of mitochondria in reperfusion injury and cardioprotection

(2010) Andrew P. Halestrap   BIOCHEMICAL SOCIETY TRANSACTIONS

In vivo hyperoxic preconditioning protects against rat-heart ischemia/reperfusion injury by inhibiting mitochondrial permeability transition pore opening and cytochrome c release

(2010) G. Petrosillo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neuroprotective Signaling Pathways are Modulated by Adenosine in the Anoxia Tolerant Turtle

(2010) Gauri H Nayak et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mitochondrial physiology of diapausing and developing embryos of the annual killifish Austrofundulus limnaeus: implications for extreme anoxia tolerance

(2010) Jeffrey M. Duerr et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

Regulation of AMPA Receptor Currents by Mitochondrial ATP-Sensitive K+ Channels in Anoxic Turtle Neurons

(2010) George Zivkovic et al.   JOURNAL OF NEUROPHYSIOLOGY

Molecular mechanisms of necroptosis: an ordered cellular explosion

(2010) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Mitochondrial Regulation of Cell Survival and Death During Low-Oxygen Conditions

(2009) Colleen M. Snyder et al.   ANTIOXIDANTS & REDOX SIGNALING

Immediate neuronal preconditioning by NS1619

(2009) Tamás Gáspár et al.   BRAIN RESEARCH

Signal transduction and reactive species

(2009) Henry Jay Forman   FREE RADICAL BIOLOGY AND MEDICINE

Reversible Cyclosporin A-sensitive Mitochondrial Depolarization Occurs within Minutes of Stroke Onset in Mouse Somatosensory Cortexin Vivo

(2009) Ran R. Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A CaPful of mechanisms regulating the mitochondrial permeability transition

(2009) Fabio Di Lisa et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Modulation of stress proteins and apoptotic regulators in the anoxia tolerant turtle brain

(2009) Shailaja Kesaraju et al.   JOURNAL OF NEUROCHEMISTRY

AMPK in the brain: its roles in energy balance and neuroprotection

(2009) Gabriele V. Ronnett et al.   JOURNAL OF NEUROCHEMISTRY

Phosphorylation of translation factors in response to anoxia in turtles, Trachemys scripta elegans: role of the AMP-activated protein kinase and target of rapamycin signalling pathways

(2009) Mark H. Rider et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Cation-Chloride Cotransporters and Neuronal Function

(2009) Peter Blaesse et al.   NEURON

NCLX is an essential component of mitochondrial Na+/Ca2+ exchange

(2009) R. Palty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential regulation of AMP-activated kinase and AKT kinase in response to oxygen availability in crucian carp (Carassius carassius)

(2008) Kåre-Olav Stensløkken et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Adenosine A1 receptor activation mediates NMDA receptor activity in a pertussis toxin-sensitive manner during normoxia but not anoxia in turtle cortical neurons

(2008) Matthew Edward Pamenter et al.   BRAIN RESEARCH

Mitochondrial complex III regulates hypoxic activation of HIF

(2008) T Klimova et al.   CELL DEATH AND DIFFERENTIATION

Biology of HIF-1α

(2008) A Weidemann et al.   CELL DEATH AND DIFFERENTIATION

Cardioprotection

(2008) Gerd Heusch et al.   CIRCULATION

Evidence of anoxia-induced channel arrest in the brain of the goldfish (Carassius auratus)

(2008) Michael P. Wilkie et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

The zebrafish embryo as a dynamic model of anoxia tolerance

(2008) Bryce A. Mendelsohn et al.   DEVELOPMENTAL DYNAMICS

Preliminary evidence of neuronal regeneration in the anoxia tolerant vertebrate brain

(2008) Shailaja Kesaraju et al.   EXPERIMENTAL NEUROLOGY

Thiol chemistry and specificity in redox signaling

(2008) Christine C. Winterbourn et al.   FREE RADICAL BIOLOGY AND MEDICINE

AMP-activated protein kinase activity during metabolic rate depression in the hypoxic goldfish, Carassius auratus

(2008) L. A. Jibb et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

 -Opioid receptor antagonism induces NMDA receptor-dependent excitotoxicity in anoxic turtle cortex

(2008) M. E. Pamenter et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Delayed neuronal preconditioning by NS1619 is independent of calcium activated potassium channels

(2008) Tamás Gáspár et al.   JOURNAL OF NEUROCHEMISTRY

Endogenous neuroprotection: Mitochondria as gateways to cerebral preconditioning?

(2008) Ulrich Dirnagl et al.   NEUROPHARMACOLOGY

Expression of genes involved in excitatory neurotransmission in anoxic crucian carp (Carassius carassius) brain

(2008) Stian Ellefsen et al.   PHYSIOLOGICAL GENOMICS

Expression of genes involved in GABAergic neurotransmission in anoxic crucian carp brain (Carassius carassius)

(2008) Stian Ellefsen et al.   PHYSIOLOGICAL GENOMICS

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

(2008) Jerry E. Chipuk et al.   TRENDS IN CELL BIOLOGY

Mitochondrial ATP-sensitive K+channels regulate NMDAR activity in the cortex of the anoxic western painted turtle

(2007) Matthew Edward Pamenter et al.   JOURNAL OF PHYSIOLOGY-LONDON