The influence of cannabinoids on generic traits of neurodegeneration

Activation of Cannabinoid CB2 Receptor–Mediated AMPK/CREB Pathway Reduces Cerebral Ischemic Injury

(2013) In-Young Choi et al.   AMERICAN JOURNAL OF PATHOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: Overview

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

In vitroandin vivomodels of Huntington's disease show alterations in the endocannabinoid system

(2013) Monica Bari et al.   FEBS Journal

Neuroinflammation and oxidative stress: Co-conspirators in the pathology of Parkinson’s disease

(2013) Juliet M. Taylor et al.   NEUROCHEMISTRY INTERNATIONAL

Sativex-like Combination of Phytocannabinoids is Neuroprotective in Malonate-Lesioned Rats, an Inflammatory Model of Huntington’s Disease: Role of CB1 and CB2 Receptors

(2012) Sara Valdeolivas et al.   ACS Chemical Neuroscience

Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?

(2012) Javier Fernández-Ruiz et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models

(2012) Eric A. Horne et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Excitotoxicity: Bridge to various triggers in neurodegenerative disorders

(2012) Ankita Mehta et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Prolonged oral cannabinoid administration prevents neuroinflammation, lowers β-amyloid levels and improves cognitive performance in Tg APP 2576 mice

(2012) Ana María Martín-Moreno et al.   Journal of Neuroinflammation

CB2 receptor and amyloid pathology in frontal cortex of Alzheimer's disease patients

(2012) Maite Solas et al.   NEUROBIOLOGY OF AGING

Δ9-tetrahydrocannabinol (Δ9-THC) exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease

(2012) C. B. Carroll et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway

(2012) Gohar Fakhfouri et al.   NEUROPHARMACOLOGY

Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro

(2012) Benjamin S. Harvey et al.   NEUROTOXICOLOGY

Monoacylglycerol Lipase Is a Therapeutic Target for Alzheimer's Disease

(2012) Rongqing Chen et al.   Cell Reports

Molecular reorganization of endocannabinoid signalling in Alzheimer’s disease

(2011) Jan Mulder et al.   BRAIN

Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ9-THCV in animal models of Parkinson's disease

(2011) C García et al.   BRITISH JOURNAL OF PHARMACOLOGY

Amyloid β peptide oligomers directly activate NMDA receptors

(2011) Laura Texidó et al.   CELL CALCIUM

Neuroprotective agents: Cannabinoids

(2011) A.J. Sánchez et al.   CLINICAL IMMUNOLOGY

Neurodegenerative disease and adult neurogenesis

(2011) Beate Winner et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Toll-like receptors are key players in neurodegeneration

(2011) Daniela S. Arroyo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cannabidiol and Other Cannabinoids Reduce Microglial Activation In Vitro and In Vivo: Relevance to Alzheimer's Disease

(2011) A. M. Martin-Moreno et al.   MOLECULAR PHARMACOLOGY

A placebo-controlled, parallel-group, randomized withdrawal study of subjects with symptoms of spasticity due to multiple sclerosis who are receiving long-term Sativex® (nabiximols)

(2011) W Notcutt et al.   Multiple Sclerosis Journal

Regional changes in type 1 cannabinoid receptor availability in Parkinson's disease in vivo

(2011) Koen Van Laere et al.   NEUROBIOLOGY OF AGING

An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease

(2011) Kwang-Mook Jung et al.   NEUROBIOLOGY OF AGING

Mitochondrial dysfunction in brain aging: Role of oxidative stress and cardiolipin

(2011) Giuseppe Paradies et al.   NEUROCHEMISTRY INTERNATIONAL

[125I]SD-7015 reveals fine modalities of CB1 cannabinoid receptor density in the prefrontal cortex during progression of Alzheimer’s disease

(2011) Szabolcs Farkas et al.   NEUROCHEMISTRY INTERNATIONAL

Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement

(2011) Giuseppe Esposito et al.   PLoS One

Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington’s disease

(2010) Cristina Blázquez et al.   BRAIN

Endocannabinoids Prevent β-Amyloid-mediated Lysosomal Destabilization in Cultured Neurons

(2010) Janis Noonan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Retrograde Endocannabinoid Signaling and Reduced Adult Neurogenesis in Diacylglycerol Lipase Knock-out Mice

(2010) Y. Gao et al.   JOURNAL OF NEUROSCIENCE

Huntington's disease: from molecular pathogenesis to clinical treatment

(2010) Christopher A Ross et al.   LANCET NEUROLOGY

Dynamic changes of anandamide in the cerebrospinal fluid of Parkinson's disease patients

(2010) Valerio Pisani et al.   MOVEMENT DISORDERS

Intact cannabinoid CB1 receptors in the Alzheimer's disease cortex

(2010) Jasinda H. Lee et al.   NEUROCHEMISTRY INTERNATIONAL

Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease

(2010) Chiara Zuccato et al.   PHYSIOLOGICAL REVIEWS

Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases

(2009) Xiao-xia Dong et al.   ACTA PHARMACOLOGICA SINICA

Microglia-aging: Roles of microglial lysosome- and mitochondria-derived reactive oxygen species in brain aging

(2009) Hiroshi Nakanishi et al.   BEHAVIOURAL BRAIN RESEARCH

Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity

(2009) Javier Palazuelos et al.   BRAIN

Neuroglia in neurodegeneration

(2009) Michael T. Heneka et al.   BRAIN RESEARCH REVIEWS

APP transgenic modeling of Alzheimer’s disease: mechanisms of neurodegeneration and aberrant neurogenesis

(2009) Leslie Crews et al.   Brain Structure & Function

The endocannabinoid system as a target for the treatment of motor dysfunction

(2009) Javier Fernández-Ruiz   BRITISH JOURNAL OF PHARMACOLOGY

Cannabidiol Targets Mitochondria to Regulate Intracellular Ca2+ Levels

(2009) D. Ryan et al.   JOURNAL OF NEUROSCIENCE

Cannabinoids attenuate the effects of aging upon neuroinflammation and neurogenesis

(2009) Yannick Marchalant et al.   NEUROBIOLOGY OF DISEASE

Systemic inflammation and disease progression in Alzheimer disease

(2009) C. Holmes et al.   NEUROLOGY

Cannabinoid receptor activation reduces TNFα-Induced surface localization of AMPAR-type glutamate receptors and excitotoxicity

(2009) Pingwei Zhao et al.   NEUROPHARMACOLOGY

BDNF regulates neuronal sensitivity to endocannabinoids

(2009) Patrick Maison et al.   NEUROSCIENCE LETTERS

Impairment of developmental stem cell-mediated striatal neurogenesis and pluripotency genes in a knock-in model of Huntington's disease

(2009) A. E. Molero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammation in Alzheimer's disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors

(2009) Antero Salminen et al.   PROGRESS IN NEUROBIOLOGY

The role of lysosomal rupture in neuronal death

(2009) Tetsumori Yamashima et al.   PROGRESS IN NEUROBIOLOGY

Reviews: Current Concepts in Alzheimer's Disease: A Multidisciplinary Review

(2008) Ludovico Minati et al.   American Journal of Alzheimers Disease and Other Dementias

Parkinson's disease: The syndrome, the pathogenesis and pathophysiology

(2008) Anna L. Bartels et al.   CORTEX

AAV–BDNF mediated attenuation of quinolinic acid-induced neuropathology and motor function impairment

(2008) A P Kells et al.   GENE THERAPY

Aging: An important factor for the pathogenesis of neurodegenerative diseases

(2008) Tahira Farooqui et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Glial expression of cannabinoid CB2 receptors and fatty acid amide hydrolase are beta amyloid–linked events in Down’s syndrome

(2008) E. Núñez et al.   NEUROSCIENCE

Neuroinflammation: Implications for the Pathogenesis and Molecular Diagnosis of Alzheimer's Disease

(2007) Leonel E. Rojo et al.   ARCHIVES OF MEDICAL RESEARCH

Symptom-related changes of endocannabinoid and palmitoylethanolamide levels in brain areas of R6/2 mice, a transgenic model of Huntington's disease

(2007) Tiziana Bisogno et al.   NEUROCHEMISTRY INTERNATIONAL

Cortical expression of brain derived neurotrophic factor and type-1 cannabinoid receptor after striatal excitotoxic lesions

(2007) Z. De March et al.   NEUROSCIENCE