In vitroandin vivomodels of Huntington's disease show alterations in the endocannabinoid system

Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models

(2012) Eric A. Horne et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion

(2012) J.- M. Lee et al.   NEUROLOGY

Unbalance of CB1 receptors expressed in GABAergic and glutamatergic neurons in a transgenic mouse model of Huntington's disease

(2011) Valentina Chiodi et al.   NEUROBIOLOGY OF DISEASE

Brain-Derived Neurotrophic Factor in Patients with Huntington's Disease

(2011) Chiara Zuccato et al.   PLoS One

Emerging roles for cholesterol in Huntington's disease

(2011) Marta Valenza et al.   TRENDS IN NEUROSCIENCES

Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington’s disease

(2010) Cristina Blázquez et al.   BRAIN

Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington's disease

(2010) EL Scotter et al.   BRITISH JOURNAL OF PHARMACOLOGY

Enol Carbamates as Inhibitors of Fatty Acid Amide Hydrolase (FAAH) Endowed with High Selectivity for FAAH over the Other Targets of the Endocannabinoid System

(2010) Sonia Gattinoni et al.   ChemMedChem

Novel Natural and Synthetic Ligands of the Endocannabinoid System

(2010) Lumir Hanus et al.   CURRENT MEDICINAL CHEMISTRY

CB1 Cannabinoid Receptors and their Associated Proteins

(2010) Allyn Howlett et al.   CURRENT MEDICINAL CHEMISTRY

Receptors and Channels Targeted by Synthetic Cannabinoid Receptor Agonists and Antagonists

(2010) R. Pertwee   CURRENT MEDICINAL CHEMISTRY

Endocannabinoids as Regulators of Transient Receptor Potential (TRP)Channels: a Further Opportunity to Develop New Endocannabinoid-Based Therapeutic Drugs

(2010) V. Marzo et al.   CURRENT MEDICINAL CHEMISTRY

Cannabinoid CB2 Receptors in Health and Disease

(2010) K. Patel et al.   CURRENT MEDICINAL CHEMISTRY

The endocannabinoid system and amyloid-related diseases

(2010) Lourdes Ruiz-Valdepeñas et al.   EXPERIMENTAL NEUROLOGY

The endocannabinoid system in the inflammatory and neurodegenerative processes of multiple sclerosis and of amyotrophic lateral sclerosis

(2010) Silvia Rossi et al.   EXPERIMENTAL NEUROLOGY

Brain-Derived Neurotrophic Factor Controls Cannabinoid CB1 Receptor Function in the Striatum

(2010) V. De Chiara et al.   JOURNAL OF NEUROSCIENCE

Characterization of mice lacking candidate N-acyl ethanolamine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo

(2010) Gabriel M. Simon et al.   Molecular BioSystems

The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors

(2010) William R Marrs et al.   NATURE NEUROSCIENCE

DAG Lipase Involvement in Depolarization-Induced Suppression of Inhibition: Does Endocannabinoid Biosynthesis Always Meet the Demand?

(2010) Rogier Min et al.   NEUROSCIENTIST

Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease

(2010) Chiara Zuccato et al.   PHYSIOLOGICAL REVIEWS

Characterization of the Endocannabinoid System in Mouse Embryonic Stem Cells

(2010) Monica Bari et al.   STEM CELLS AND DEVELOPMENT

Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity

(2009) Javier Palazuelos et al.   BRAIN

From endocannabinoid profiling to ‘endocannabinoid therapeutics’

(2009) Alessia Ligresti et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Characterization of the Endocannabinoid System in Human Spermatozoa and Involvement of Transient Receptor Potential Vanilloid 1 Receptor in Their Fertilizing Ability

(2009) F. Francavilla et al.   ENDOCRINOLOGY

Cannabinoid CB2receptor agonists protect the striatum against malonate toxicity: Relevance for Huntington's disease

(2009) Onintza Sagredo et al.   GLIA

Characterization of the Endocannabinoid System in Human Neuronal Cells and Proteomic Analysis of Anandamide-induced Apoptosis

(2009) Nicoletta Pasquariello et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid rafts regulate 2-arachidonoylglycerol metabolism and physiological activity in the striatum

(2009) Mauro Maccarrone et al.   JOURNAL OF NEUROCHEMISTRY

A pilot study using nabilone for symptomatic treatment in Huntington's disease

(2009) Adrienne Curtis et al.   MOVEMENT DISORDERS

The Endocannabinoid System in Parkinsons Disease

(2008) Massimiliano Di Filippo et al.   CURRENT PHARMACEUTICAL DESIGN

The Endocannabinoid System in Huntingtons Disease

(2008) M. Pazos et al.   CURRENT PHARMACEUTICAL DESIGN

In VitroCharacterization of Embryionic ST14A-Cells

(2008) Marine Hovakimyan et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Endocannabinoid signaling as a synaptic circuit breaker in neurological disease

(2008) István Katona et al.   NATURE MEDICINE

Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum

(2008) Mauro Maccarrone et al.   NATURE NEUROSCIENCE

Symptom-related changes of endocannabinoid and palmitoylethanolamide levels in brain areas of R6/2 mice, a transgenic model of Huntington's disease

(2007) Tiziana Bisogno et al.   NEUROCHEMISTRY INTERNATIONAL